CRCGN009_HEPG2_24H:P20 Gene Set
Genes
60 genes differentially expressed following the CRCGN009_HEPG2_24H:P20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.095
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.97462
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
4.70591
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.68523
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.68474
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
4.59149
|
|
TIMP2
|
TIMP metallopeptidase inhibitor 2
|
4.1999
|
|
CBR3
|
carbonyl reductase 3
|
4.0123
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.98293
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.67391
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.48016
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.4118
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.35677
|
|
GATA3
|
GATA binding protein 3
|
3.19946
|
|
DUSP4
|
dual specificity phosphatase 4
|
3.03378
|
|
EVL
|
Enah/Vasp-like
|
2.95947
|
|
SMAD3
|
SMAD family member 3
|
2.95766
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.88247
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.84351
|
|
TENT4A
|
terminal nucleotidyltransferase 4A
|
2.74371
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.64385
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.61505
|
|
RBKS
|
ribokinase
|
2.34729
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.33311
|
|
WDR7
|
WD repeat domain 7
|
2.22009
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.17468
|
|
POP7
|
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
|
2.12472
|
|
JADE2
|
jade family PHD finger 2
|
2.08555
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.0554
|
|
EPHA3
|
EPH receptor A3
|
2.03527
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NGRN
|
neugrin, neurite outgrowth associated
|
-8.51739
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.65637
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.05026
|
|
DSG2
|
desmoglein 2
|
-4.96679
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.94172
|
|
ISOC1
|
isochorismatase domain containing 1
|
-4.80072
|
|
TLR4
|
toll-like receptor 4
|
-4.54933
|
|
CD320
|
CD320 molecule
|
-4.51356
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.37132
|
|
LDHD
|
lactate dehydrogenase D
|
-4.29591
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.96559
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-3.96061
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.67026
|
|
ATP6V0B
|
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
|
-3.64877
|
|
ELAC2
|
elaC ribonuclease Z 2
|
-3.62979
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.55966
|
|
CCNB2
|
cyclin B2
|
-3.40101
|
|
CSK
|
c-src tyrosine kinase
|
-3.36404
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-3.26265
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.23733
|
|
LSM6
|
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.61029
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.40795
|
|
WASHC4
|
WASH complex subunit 4
|
-2.3338
|
|
DUSP8
|
dual specificity phosphatase 8
|
-2.30424
|
|
SHTN1
|
shootin 1
|
-2.28385
|
|
CAB39
|
calcium binding protein 39
|
-2.25677
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
-2.23015
|
|
APLP1
|
amyloid beta (A4) precursor-like protein 1
|
-2.13929
|
|
FLNC
|
filamin C, gamma
|
-2.11595
|
|
CORO7-PAM16
|
CORO7-PAM16 readthrough
|
-2.07444
|
