CRCGN009_HEPG2_24H:P21 Gene Set
Genes
38 genes differentially expressed following the CRCGN009_HEPG2_24H:P21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
6.58522
|
|
CYCS
|
cytochrome c, somatic
|
4.51101
|
|
CHN1
|
chimerin 1
|
4.094
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.90035
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.38775
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.22465
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.16313
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.05272
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.04129
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.85649
|
|
UBE2A
|
ubiquitin-conjugating enzyme E2A
|
2.59758
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.35887
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.27475
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.12587
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-6.98845
|
|
TLCD3A
|
TLC domain containing 3A
|
-5.07442
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.79767
|
|
ZNF586
|
zinc finger protein 586
|
-3.70605
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.68211
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-3.55163
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.40151
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.34726
|
|
RNF167
|
ring finger protein 167
|
-3.27326
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.20336
|
|
HYOU1
|
hypoxia up-regulated 1
|
-3.1399
|
|
THAP11
|
THAP domain containing 11
|
-3.0537
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.00813
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.89934
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.87435
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.85387
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.81706
|
|
CSK
|
c-src tyrosine kinase
|
-2.69809
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.61485
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.26662
|
|
PEG10
|
paternally expressed 10
|
-2.24381
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.16273
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.09327
|
|
TLR4
|
toll-like receptor 4
|
-2.06655
|
