CRCGN009_HEPG2_24H:P22 Gene Set
Genes
43 genes differentially expressed following the CRCGN009_HEPG2_24H:P22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
7.05509
|
|
CYCS
|
cytochrome c, somatic
|
5.81483
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
5.06832
|
|
STIMATE
|
STIM activating enhancer
|
4.82492
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.46819
|
|
NOTCH1
|
notch 1
|
4.40554
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.33114
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.02239
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
3.69491
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.27256
|
|
PRR15L
|
proline rich 15-like
|
3.17243
|
|
MAP7
|
microtubule-associated protein 7
|
3.14261
|
|
SLC38A6
|
solute carrier family 38, member 6
|
2.90118
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.69748
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.59756
|
|
TBP
|
TATA box binding protein
|
2.24163
|
|
EMC2
|
ER membrane protein complex subunit 2
|
2.22036
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.18234
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.17458
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.15615
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.00523
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.90838
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.84429
|
|
TUBB6
|
tubulin, beta 6 class V
|
-4.99622
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-4.92755
|
|
TLR4
|
toll-like receptor 4
|
-4.30134
|
|
CCNB1
|
cyclin B1
|
-4.1053
|
|
GNAS
|
GNAS complex locus
|
-3.49109
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-3.28748
|
|
CSK
|
c-src tyrosine kinase
|
-3.15424
|
|
EGF
|
epidermal growth factor
|
-3.09428
|
|
CDC20
|
cell division cycle 20
|
-3.03655
|
|
HYOU1
|
hypoxia up-regulated 1
|
-3.03333
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.93059
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.71408
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.50143
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-2.43342
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.33934
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.19846
|
|
ASAH1
|
N-acylsphingosine amidohydrolase (acid ceramidase) 1
|
-2.1203
|
|
NUDT18
|
nudix (nucleoside diphosphate linked moiety X)-type motif 18
|
-2.06978
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.02006
|
|
ZNF586
|
zinc finger protein 586
|
-2.00738
|
