CRCGN009_HEPG2_24H:P24 Gene Set
Genes
51 genes differentially expressed following the CRCGN009_HEPG2_24H:P24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.04794
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.04767
|
|
UBQLN2
|
ubiquilin 2
|
3.84029
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.79428
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.74739
|
|
HOXA10
|
homeobox A10
|
3.36039
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
3.20102
|
|
GPATCH8
|
G patch domain containing 8
|
3.19869
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.18719
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.15977
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
3.11418
|
|
FOXJ3
|
forkhead box J3
|
3.11367
|
|
LCN2
|
lipocalin 2
|
3.0932
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.94288
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.82389
|
|
STIMATE
|
STIM activating enhancer
|
2.66878
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.61831
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.60322
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.49238
|
|
EVL
|
Enah/Vasp-like
|
2.44347
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.34943
|
|
MAP7
|
microtubule-associated protein 7
|
2.30597
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
2.25915
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.23744
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
2.20785
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
2.14129
|
|
POLA1
|
polymerase (DNA directed), alpha 1, catalytic subunit
|
2.12312
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.09148
|
|
SIAH2
|
siah E3 ubiquitin protein ligase 2
|
2.05871
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.87137
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.76042
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-5.24115
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.9253
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.75255
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.33616
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.28351
|
|
NVL
|
nuclear VCP-like
|
-3.25865
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.22771
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.96148
|
|
RAI14
|
retinoic acid induced 14
|
-2.80838
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-2.77272
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.67172
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.65898
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.49321
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.31626
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.28505
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.27889
|
|
SOX12
|
SRY (sex determining region Y)-box 12
|
-2.15558
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.08833
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.06423
|
|
RNF2
|
ring finger protein 2
|
-2.00864
|
