| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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79 genes differentially expressed following the CRCGN010_HEPG2_24H:A03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYLK | myosin light chain kinase | 5.21926 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.16341 |
| NOSIP | nitric oxide synthase interacting protein | 5.13307 |
| CSK | c-src tyrosine kinase | 4.76885 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.75805 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.73599 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.4514 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 4.31341 |
| UBQLN2 | ubiquilin 2 | 4.30858 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.27392 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.98104 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 3.96812 |
| MAP7 | microtubule-associated protein 7 | 3.87871 |
| ABHD6 | abhydrolase domain containing 6 | 3.86707 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 3.76909 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.68831 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.58688 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.38531 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.25827 |
| CEP57 | centrosomal protein 57kDa | 2.96104 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.8969 |
| PRR15L | proline rich 15-like | 2.83488 |
| CDC45 | cell division cycle 45 | 2.65222 |
| NVL | nuclear VCP-like | 2.62475 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.62253 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.53377 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.53326 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.52619 |
| TBP | TATA box binding protein | 2.52571 |
| AXIN1 | axin 1 | 2.4789 |
| MEST | mesoderm specific transcript | 2.43108 |
| CYCS | cytochrome c, somatic | 2.36262 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | 2.28899 |
| TSPAN13 | tetraspanin 13 | 2.25731 |
| BCL7C | B-cell CLL/lymphoma 7C | 2.20135 |
| UFM1 | ubiquitin-fold modifier 1 | 2.1815 |
| SATB1 | SATB homeobox 1 | 2.12123 |
| LOC122526780 | uncharacterized LOC122526780 | 2.11988 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 2.09939 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 2.08684 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 2.07492 |
| THAP7 | THAP domain containing 7 | 2.05329 |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 | 2.03963 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNM1L | dynamin 1-like | -9.33921 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -6.71092 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.93921 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -5.71792 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.29668 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -5.23686 |
| CCNB2 | cyclin B2 | -5.1148 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -5.10326 |
| TLR4 | toll-like receptor 4 | -4.94547 |
| PCNA | proliferating cell nuclear antigen | -4.61127 |
| LDHD | lactate dehydrogenase D | -4.51221 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -4.46329 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.45472 |
| TRIB3 | tribbles pseudokinase 3 | -4.44995 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.25107 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.21952 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.18343 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -4.09106 |
| YME1L1 | YME1-like 1 ATPase | -3.93475 |
| CCDC86 | coiled-coil domain containing 86 | -3.9045 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -3.68789 |
| HMG20B | high mobility group 20B | -3.5879 |
| DDIT4 | DNA-damage-inducible transcript 4 | -3.5317 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | -3.40683 |
| GNAS | GNAS complex locus | -3.39438 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.25517 |
| ZNF274 | zinc finger protein 274 | -3.10476 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.55987 |
| SQSTM1 | sequestosome 1 | -2.51538 |
| CHEK1 | checkpoint kinase 1 | -2.40588 |
| AURKA | aurora kinase A | -2.38418 |
| TWF2 | twinfilin actin binding protein 2 | -2.36943 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.18962 |
| TRIB1 | tribbles pseudokinase 1 | -2.18328 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | -2.05675 |
| MDH1 | malate dehydrogenase 1, NAD (soluble) | -2.03494 |
