| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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97 genes differentially expressed following the CRCGN010_HEPG2_24H:A04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 8.26891 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 6.55906 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 6.43902 |
| KLHL21 | kelch-like family member 21 | 5.98462 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.1359 |
| EVL | Enah/Vasp-like | 4.117 |
| MCM3 | minichromosome maintenance complex component 3 | 4.10113 |
| ATP11B | ATPase, class VI, type 11B | 4.05336 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.892 |
| LCN2 | lipocalin 2 | 3.60274 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 3.4513 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.2892 |
| SATB1 | SATB homeobox 1 | 3.16942 |
| CHN1 | chimerin 1 | 3.0194 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.83131 |
| BZW2 | basic leucine zipper and W2 domains 2 | 2.74953 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 2.64632 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.5896 |
| DIPK1A | divergent protein kinase domain 1A | 2.55013 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 2.53072 |
| COBL | cordon-bleu WH2 repeat protein | 2.48909 |
| MICALL1 | MICAL-like 1 | 2.47564 |
| ADRB2 | adrenoceptor beta 2, surface | 2.46163 |
| HOXA10-HOXA9 | HOXA10-HOXA9 readthrough | 2.45663 |
| MSRA | methionine sulfoxide reductase A | 2.42013 |
| CYCS | cytochrome c, somatic | 2.41478 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 | 2.41061 |
| MCOLN1 | mucolipin 1 | 2.39869 |
| HNF4G | hepatocyte nuclear factor 4, gamma | 2.38255 |
| DENND2D | DENN/MADD domain containing 2D | 2.36898 |
| CCDC92 | coiled-coil domain containing 92 | 2.30101 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.29687 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 2.28476 |
| PLS1 | plastin 1 | 2.28458 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.23422 |
| E2F2 | E2F transcription factor 2 | 2.22055 |
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 | 2.21204 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.20872 |
| LSR | lipolysis stimulated lipoprotein receptor | 2.17432 |
| HOXA10 | homeobox A10 | 2.17024 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 | 2.16913 |
| CLDN15 | claudin 15 | 2.1411 |
| PICK1 | protein interacting with PRKCA 1 | 2.10703 |
| PNKP | polynucleotide kinase 3'-phosphatase | 2.08172 |
| DELE1 | DAP3 binding cell death enhancer 1 | 2.07614 |
| SCN4A | sodium channel, voltage gated, type IV alpha subunit | 2.06925 |
| ANXA13 | annexin A13 | 2.04631 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.03654 |
| CCL1 | chemokine (C-C motif) ligand 1 | 2.03333 |
| SRPK3 | SRSF protein kinase 3 | 2.01264 |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) | 2.01149 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -6.76732 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -6.68054 |
| FASTKD5 | FAST kinase domains 5 | -5.95884 |
| VAT1 | vesicle amine transport 1 | -4.6979 |
| MAPK13 | mitogen-activated protein kinase 13 | -4.5341 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -4.01986 |
| SLC35F2 | solute carrier family 35, member F2 | -3.71523 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.0638 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.9697 |
| TRIB3 | tribbles pseudokinase 3 | -2.95237 |
| ZNF586 | zinc finger protein 586 | -2.8358 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.76867 |
| GDF15 | growth differentiation factor 15 | -2.74912 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | -2.65451 |
| COG7 | component of oligomeric golgi complex 7 | -2.62413 |
| GTPBP8 | GTP-binding protein 8 (putative) | -2.62163 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.60378 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.56617 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.4827 |
| ISOC1 | isochorismatase domain containing 1 | -2.41644 |
| TUBB6 | tubulin, beta 6 class V | -2.37882 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.3639 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.324 |
| MRPS16 | mitochondrial ribosomal protein S16 | -2.32266 |
| IER3 | immediate early response 3 | -2.31213 |
| DUSP6 | dual specificity phosphatase 6 | -2.29829 |
| TLR4 | toll-like receptor 4 | -2.29554 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.2712 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.2574 |
| SCAND1 | SCAN domain containing 1 | -2.24554 |
| SMIM10L1 | small integral membrane protein 10 like 1 | -2.22267 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.21335 |
| CCNH | cyclin H | -2.19452 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -2.17386 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.14041 |
| TAF11 | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa | -2.1369 |
| PRR13 | proline rich 13 | -2.13289 |
| PRPF4 | pre-mRNA processing factor 4 | -2.108 |
| DSG2 | desmoglein 2 | -2.08186 |
| SIX1 | SIX homeobox 1 | -2.07593 |
| METTL9 | methyltransferase like 9 | -2.05373 |
| ADI1 | acireductone dioxygenase 1 | -2.04481 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -2.04019 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -2.01676 |
| FGF14 | fibroblast growth factor 14 | -2.01321 |
| HAT1 | histone acetyltransferase 1 | -2.00776 |
