CRCGN010_HEPG2_24H:A11 Gene Set
Genes
47 genes differentially expressed following the CRCGN010_HEPG2_24H:A11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
5.34361
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.77095
|
|
SFTPB
|
surfactant protein B
|
4.59789
|
|
CYCS
|
cytochrome c, somatic
|
4.35653
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
4.22409
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
4.14734
|
|
NMU
|
neuromedin U
|
3.70295
|
|
E2F2
|
E2F transcription factor 2
|
3.36433
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.34666
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.32308
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.10635
|
|
CBR3
|
carbonyl reductase 3
|
3.08839
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
3.06656
|
|
PRR15L
|
proline rich 15-like
|
3.04179
|
|
CSK
|
c-src tyrosine kinase
|
3.0171
|
|
JADE2
|
jade family PHD finger 2
|
2.96141
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.86465
|
|
POLG2
|
polymerase (DNA directed), gamma 2, accessory subunit
|
2.48558
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
2.42176
|
|
NDUFA1
|
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
|
2.39853
|
|
CHN1
|
chimerin 1
|
2.30832
|
|
CCNC
|
cyclin C
|
2.18487
|
|
OLA1
|
Obg-like ATPase 1
|
2.17634
|
|
GATA2
|
GATA binding protein 2
|
2.12797
|
|
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1
|
2.12028
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.08899
|
|
RANBP2
|
RAN binding protein 2
|
2.05476
|
|
DHDDS
|
dehydrodolichyl diphosphate synthase
|
2.04562
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.00104
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-8.42225
|
|
CCNB2
|
cyclin B2
|
-6.4659
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-4.78456
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.55584
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.77609
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.66861
|
|
TLR4
|
toll-like receptor 4
|
-3.44718
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.26296
|
|
ISOC1
|
isochorismatase domain containing 1
|
-3.115
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-3.05099
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.00032
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.97553
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.87845
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.52432
|
|
SCRIB
|
scribbled planar cell polarity protein
|
-2.41682
|
|
SCAND1
|
SCAN domain containing 1
|
-2.32388
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.31641
|
|
RFPL2
|
ret finger protein-like 2
|
-2.10081
|
