| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | oxyquinoline 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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71 genes differentially expressed following the CRCGN010_HEPG2_24H:A12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 5.2545 |
| MOK | MOK protein kinase | 5.15095 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 5.1419 |
| EPHB2 | EPH receptor B2 | 4.62026 |
| CHMP6 | charged multivesicular body protein 6 | 4.1487 |
| PRR15L | proline rich 15-like | 4.06225 |
| SLC75A1 | solute carrier family 75 member 1 | 3.9599 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 3.6549 |
| HSPA8 | heat shock 70kDa protein 8 | 3.35128 |
| GATA3 | GATA binding protein 3 | 3.18882 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 3.15805 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.03965 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.01157 |
| PMM2 | phosphomannomutase 2 | 2.8081 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.7394 |
| BAD | BCL2-associated agonist of cell death | 2.71572 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 2.58055 |
| CCNE2 | cyclin E2 | 2.34617 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.3236 |
| TEX10 | testis expressed 10 | 2.2781 |
| CA5A | carbonic anhydrase VA, mitochondrial | 2.2709 |
| CSK | c-src tyrosine kinase | 2.2676 |
| COL9A2 | collagen, type IX, alpha 2 | 2.26585 |
| AHSG | alpha-2-HS-glycoprotein | 2.25483 |
| TYRP1 | tyrosinase-related protein 1 | 2.19255 |
| PRR5L | proline rich 5 like | 2.1921 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 2.155 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 2.15075 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 2.14555 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.1354 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.0859 |
| NUCB2 | nucleobindin 2 | 2.0652 |
| GPC3 | glypican 3 | 2.0651 |
| ADI1 | acireductone dioxygenase 1 | 2.04205 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 2.03765 |
| NANOS2 | nanos homolog 2 (Drosophila) | 2.01465 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -7.9227 |
| TLR4 | toll-like receptor 4 | -6.6451 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.47355 |
| SLC35F2 | solute carrier family 35, member F2 | -5.2895 |
| LDHD | lactate dehydrogenase D | -5.15725 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -5.0673 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.04075 |
| VAT1 | vesicle amine transport 1 | -4.92215 |
| COPS7A | COP9 signalosome subunit 7A | -4.8074 |
| PCNA | proliferating cell nuclear antigen | -4.23 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.96805 |
| STMN1 | stathmin 1 | -3.5171 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -3.34405 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.2579 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.87365 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.77155 |
| PRPF4 | pre-mRNA processing factor 4 | -2.53437 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.5063 |
| CYP2C18 | cytochrome P450, family 2, subfamily C, polypeptide 18 | -2.50342 |
| PERP | PERP, TP53 apoptosis effector | -2.45925 |
| TRAPPC2 | trafficking protein particle complex 2 | -2.32915 |
| MYL9 | myosin, light chain 9, regulatory | -2.25585 |
| CDC25B | cell division cycle 25B | -2.24665 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -2.2384 |
| TLR3 | toll-like receptor 3 | -2.1959 |
| DGKA | diacylglycerol kinase, alpha 80kDa | -2.1865 |
| COPS6 | COP9 signalosome subunit 6 | -2.16087 |
| EXOSC5 | exosome component 5 | -2.1592 |
| CSTA | cystatin A (stefin A) | -2.1078 |
| DAND5 | DAN domain family member 5, BMP antagonist | -2.0611 |
| KIAA0319L | KIAA0319-like | -2.0481 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.0346 |
| UPK1A | uroplakin 1A | -2.02995 |
| EDNRA | endothelin receptor type A | -2.02737 |
| HEBP2 | heme binding protein 2 | -2.01785 |
