| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hexachlorobenzene 0.25 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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75 genes differentially expressed following the CRCGN010_HEPG2_24H:A16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 10.0 |
| PRR15L | proline rich 15-like | 9.88875 |
| DENND2D | DENN/MADD domain containing 2D | 5.64755 |
| UBQLN2 | ubiquilin 2 | 5.0753 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.90935 |
| PMM2 | phosphomannomutase 2 | 3.70305 |
| PLSCR1 | phospholipid scramblase 1 | 3.54233 |
| AXIN1 | axin 1 | 3.23495 |
| MEST | mesoderm specific transcript | 3.1853 |
| NUCB2 | nucleobindin 2 | 3.1736 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | 3.1319 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.04325 |
| SFTPB | surfactant protein B | 2.82365 |
| JADE2 | jade family PHD finger 2 | 2.73025 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.7227 |
| CYCS | cytochrome c, somatic | 2.63315 |
| TESK1 | testis-specific kinase 1 | 2.60655 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.5069 |
| HSPA8 | heat shock 70kDa protein 8 | 2.40047 |
| TENT4A | terminal nucleotidyltransferase 4A | 2.3985 |
| ZNF589 | zinc finger protein 589 | 2.3664 |
| NLRP4 | NLR family, pyrin domain containing 4 | 2.31775 |
| PLSCR3 | phospholipid scramblase 3 | 2.2352 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | 2.21652 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.20713 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | 2.2029 |
| MMP2 | matrix metallopeptidase 2 | 2.1905 |
| TMEM94 | transmembrane protein 94 | 2.15525 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 2.1333 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.11565 |
| KAT6B | K(lysine) acetyltransferase 6B | 2.11071 |
| NOSIP | nitric oxide synthase interacting protein | 2.10515 |
| ZWINT | ZW10 interacting kinetochore protein | 2.06265 |
| OXCT1 | 3-oxoacid CoA transferase 1 | 2.05785 |
| CYP11B1 | cytochrome P450, family 11, subfamily B, polypeptide 1 | 2.04235 |
| RCC1L | RCC1 like | 2.0152 |
| ZMYM3 | zinc finger, MYM-type 3 | 2.01395 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.0066 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.03135 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -4.9637 |
| SCAND1 | SCAN domain containing 1 | -4.3318 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.064 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.6762 |
| WASHC4 | WASH complex subunit 4 | -3.57392 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.395 |
| GDF15 | growth differentiation factor 15 | -3.2524 |
| SOAT2 | sterol O-acyltransferase 2 | -2.9467 |
| HEATR1 | HEAT repeat containing 1 | -2.85913 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.77268 |
| OSR2 | odd-skipped related transciption factor 2 | -2.65355 |
| CCNH | cyclin H | -2.57145 |
| APOBEC3F | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F | -2.4891 |
| FUT5 | fucosyltransferase 5 (alpha (1,3) fucosyltransferase) | -2.4262 |
| SLC6A11 | solute carrier family 6 (neurotransmitter transporter), member 11 | -2.3893 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.3143 |
| UFM1 | ubiquitin-fold modifier 1 | -2.24415 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 | -2.23885 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.20545 |
| MAG | myelin associated glycoprotein | -2.1955 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 | -2.1927 |
| CERS1 | ceramide synthase 1 | -2.1821 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | -2.1691 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -2.16885 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 | -2.1678 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.14047 |
| NPY | neuropeptide Y | -2.13435 |
| SCT | secretin | -2.1335 |
| MATN4 | matrilin 4 | -2.1261 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 | -2.11275 |
| CDC42 | cell division cycle 42 | -2.11063 |
| TGM1 | transglutaminase 1 | -2.0511 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -2.0194 |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 | -2.01245 |
| SNX2 | sorting nexin 2 | -2.0114 |
