| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hexachlorobenzene 0.13 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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64 genes differentially expressed following the CRCGN010_HEPG2_24H:A17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 8.13269 |
| CHMP6 | charged multivesicular body protein 6 | 7.93956 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.78804 |
| E2F2 | E2F transcription factor 2 | 4.55244 |
| LPAR2 | lysophosphatidic acid receptor 2 | 4.16017 |
| PRKCH | protein kinase C, eta | 4.13589 |
| PRR15L | proline rich 15-like | 3.91139 |
| CSK | c-src tyrosine kinase | 3.15339 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 3.12573 |
| SFTPB | surfactant protein B | 2.9751 |
| NMU | neuromedin U | 2.96439 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.86545 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 2.8561 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.84703 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.82879 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.77797 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.76037 |
| CHN1 | chimerin 1 | 2.74705 |
| RPL39L | ribosomal protein L39-like | 2.54497 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 2.51241 |
| TEX10 | testis expressed 10 | 2.4188 |
| MEST | mesoderm specific transcript | 2.38659 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.38097 |
| CYCS | cytochrome c, somatic | 2.37237 |
| GPATCH8 | G patch domain containing 8 | 2.3685 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.23093 |
| HMOX1 | heme oxygenase 1 | 2.21592 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 2.20548 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.19849 |
| SNX7 | sorting nexin 7 | 2.07182 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 2.06263 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.03156 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KDM3A | lysine (K)-specific demethylase 3A | -7.9488 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -6.88798 |
| ZNF586 | zinc finger protein 586 | -5.75194 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.89714 |
| SLC35F2 | solute carrier family 35, member F2 | -4.83522 |
| TSPAN4 | tetraspanin 4 | -4.75848 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.71365 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.41887 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.40239 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.58583 |
| RGS2 | regulator of G-protein signaling 2 | -3.52214 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.39874 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.34006 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.32672 |
| CCNB1 | cyclin B1 | -3.07029 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.04854 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.0405 |
| YME1L1 | YME1-like 1 ATPase | -3.00628 |
| ADI1 | acireductone dioxygenase 1 | -2.94626 |
| VDAC1 | voltage-dependent anion channel 1 | -2.40054 |
| KIF14 | kinesin family member 14 | -2.25553 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.2276 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.21934 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -2.20912 |
| RBM34 | RNA binding motif protein 34 | -2.19752 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.12696 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.09895 |
| TBX3 | T-box 3 | -2.06428 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.04804 |
| CDC20 | cell division cycle 20 | -2.04202 |
| PPOX | protoporphyrinogen oxidase | -2.0137 |
| COL7A1 | collagen, type VII, alpha 1 | -2.01301 |
