CRCGN010_HEPG2_24H:A18 Gene Set
Genes
42 genes differentially expressed following the CRCGN010_HEPG2_24H:A18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
6.79596
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
5.25129
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.1295
|
|
UBQLN2
|
ubiquilin 2
|
4.7493
|
|
MAP7
|
microtubule-associated protein 7
|
4.6685
|
|
LOC122526780
|
uncharacterized LOC122526780
|
4.22648
|
|
CYCS
|
cytochrome c, somatic
|
4.10081
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.98828
|
|
TATDN2
|
TatD DNase domain containing 2
|
3.46064
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.32186
|
|
MYLK
|
myosin light chain kinase
|
3.15879
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.89477
|
|
STK10
|
serine/threonine kinase 10
|
2.87865
|
|
EVL
|
Enah/Vasp-like
|
2.74853
|
|
LCN2
|
lipocalin 2
|
2.7219
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.57327
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
2.50289
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.49063
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.43426
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.38353
|
|
STXBP2
|
syntaxin binding protein 2
|
2.28493
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.18368
|
|
CREG1
|
cellular repressor of E1A-stimulated genes 1
|
2.09044
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-7.25594
|
|
CDC20
|
cell division cycle 20
|
-6.84989
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.90156
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.51398
|
|
THAP11
|
THAP domain containing 11
|
-3.7342
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.30282
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.05838
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.90752
|
|
NUP85
|
nucleoporin 85kDa
|
-2.8868
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.82454
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.8045
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.6996
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-2.61304
|
|
CCNB1
|
cyclin B1
|
-2.48738
|
|
SCAND1
|
SCAN domain containing 1
|
-2.39057
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-2.16019
|
|
MAGEA2B
|
melanoma antigen family A2B
|
-2.03854
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.02294
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.01771
|
