| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hc blue no. 2 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN010_HEPG2_24H:A19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CBR3 | carbonyl reductase 3 | 8.48338 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 7.01363 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 5.01813 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 4.50215 |
| CSK | c-src tyrosine kinase | 3.64669 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.60053 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 3.45773 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.4076 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 3.31885 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.94775 |
| TAC4 | tachykinin 4 (hemokinin) | 2.93151 |
| SATB1 | SATB homeobox 1 | 2.90527 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.87362 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.69433 |
| ABHD6 | abhydrolase domain containing 6 | 2.58765 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.5653 |
| SFTPB | surfactant protein B | 2.5474 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | 2.53602 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.51109 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.4505 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.32386 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.20045 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 2.18513 |
| EPN2 | epsin 2 | 2.17147 |
| DHDDS | dehydrodolichyl diphosphate synthase | 2.13859 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.05963 |
| PRR15L | proline rich 15-like | 2.02347 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -9.91316 |
| KDM3A | lysine (K)-specific demethylase 3A | -6.90942 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.579 |
| SLC35F2 | solute carrier family 35, member F2 | -4.4591 |
| YME1L1 | YME1-like 1 ATPase | -4.41554 |
| TLR4 | toll-like receptor 4 | -4.31789 |
| VAT1 | vesicle amine transport 1 | -4.20542 |
| RAI14 | retinoic acid induced 14 | -4.16849 |
| GNAS | GNAS complex locus | -4.06588 |
| TRIB3 | tribbles pseudokinase 3 | -4.00136 |
| CCNB2 | cyclin B2 | -3.24464 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.13923 |
| PPOX | protoporphyrinogen oxidase | -2.83919 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -2.77039 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.59449 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.59348 |
| PARP2 | poly (ADP-ribose) polymerase 2 | -2.57468 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.5485 |
| VDAC1 | voltage-dependent anion channel 1 | -2.45304 |
| FASTKD5 | FAST kinase domains 5 | -2.4198 |
| ZNF586 | zinc finger protein 586 | -2.41809 |
| PRPF18 | pre-mRNA processing factor 18 | -2.41149 |
| TLCD3A | TLC domain containing 3A | -2.343 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.33022 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) | -2.26066 |
| CTSD | cathepsin D | -2.13278 |
| FGF9 | fibroblast growth factor 9 | -2.08667 |
| FAM171A1 | family with sequence similarity 171, member A1 | -2.07418 |
| ATF3 | activating transcription factor 3 | -2.05046 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.00486 |
| IFT70A | intraflagellar transport 70A | -2.00249 |
