CRCGN010_HEPG2_24H:A20 Gene Set
Genes
61 genes differentially expressed following the CRCGN010_HEPG2_24H:A20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
5.02006
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.19819
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
3.83576
|
|
MYLK
|
myosin light chain kinase
|
3.73759
|
|
EPHB2
|
EPH receptor B2
|
3.66448
|
|
NOTCH1
|
notch 1
|
3.59131
|
|
NMU
|
neuromedin U
|
3.33717
|
|
CSK
|
c-src tyrosine kinase
|
3.32942
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.31534
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.28655
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.28264
|
|
RRAGA
|
Ras-related GTP binding A
|
3.22297
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.09402
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.97774
|
|
STK10
|
serine/threonine kinase 10
|
2.89675
|
|
MEST
|
mesoderm specific transcript
|
2.81736
|
|
ANO10
|
anoctamin 10
|
2.63995
|
|
CYCS
|
cytochrome c, somatic
|
2.57725
|
|
FZD7
|
frizzled class receptor 7
|
2.5229
|
|
PMM2
|
phosphomannomutase 2
|
2.51832
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.41206
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.41093
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.34708
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.33069
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.2855
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
2.16123
|
|
CHEK2
|
checkpoint kinase 2
|
2.14575
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.09262
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-8.64347
|
|
TLCD3A
|
TLC domain containing 3A
|
-7.13384
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.73353
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.69226
|
|
RNF167
|
ring finger protein 167
|
-3.58446
|
|
NUP93
|
nucleoporin 93kDa
|
-3.55455
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.52684
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.47451
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.38164
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.36385
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.16294
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.10862
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-3.10655
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-3.04837
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.02851
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.02515
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.98804
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.91644
|
|
LDHD
|
lactate dehydrogenase D
|
-2.67552
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.64423
|
|
ZNF274
|
zinc finger protein 274
|
-2.52268
|
|
ZNF84
|
zinc finger protein 84
|
-2.34874
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.34035
|
|
DCK
|
deoxycytidine kinase
|
-2.28456
|
|
ZNF222
|
zinc finger protein 222
|
-2.2198
|
|
GNAS
|
GNAS complex locus
|
-2.19625
|
|
TBCB
|
tubulin folding cofactor B
|
-2.15977
|
|
MACF1
|
microtubule-actin crosslinking factor 1
|
-2.13115
|
|
CAPNS1
|
calpain, small subunit 1
|
-2.07403
|
|
ZNF140
|
zinc finger protein 140
|
-2.03372
|
|
ZNF134
|
zinc finger protein 134
|
-2.02637
|
|
PDCD5
|
programmed cell death 5
|
-2.01314
|
|
ZNF268
|
zinc finger protein 268
|
-2.01279
|