| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hc blue no. 2 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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64 genes differentially expressed following the CRCGN010_HEPG2_24H:A23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 8.49762 |
| CYCS | cytochrome c, somatic | 6.05232 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 4.62716 |
| CSK | c-src tyrosine kinase | 4.45916 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.39923 |
| LCN2 | lipocalin 2 | 4.29637 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.20361 |
| LOC122526780 | uncharacterized LOC122526780 | 4.15 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.14068 |
| HSPA1A | heat shock 70kDa protein 1A | 3.9837 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.86445 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 3.86234 |
| FZD7 | frizzled class receptor 7 | 3.47366 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 3.40757 |
| KLHL9 | kelch-like family member 9 | 3.29774 |
| EAPP | E2F-associated phosphoprotein | 3.19115 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.08456 |
| HYOU1 | hypoxia up-regulated 1 | 2.99304 |
| JADE2 | jade family PHD finger 2 | 2.82812 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.7951 |
| CRTAP | cartilage associated protein | 2.7837 |
| NOTCH1 | notch 1 | 2.75363 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.69359 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.54632 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.49379 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.48055 |
| TEX10 | testis expressed 10 | 2.40085 |
| MMP1 | matrix metallopeptidase 1 | 2.36527 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 2.33386 |
| SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) | 2.20225 |
| KIAA0232 | KIAA0232 | 2.1666 |
| RHOF | ras homolog family member F (in filopodia) | 2.12346 |
| EPHA3 | EPH receptor A3 | 2.06282 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDC20 | cell division cycle 20 | -10.0 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -8.45671 |
| VAT1 | vesicle amine transport 1 | -6.34418 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.67505 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -5.65637 |
| CCNB1 | cyclin B1 | -5.53913 |
| TLR4 | toll-like receptor 4 | -4.97134 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.52931 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.46571 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.35253 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -4.26453 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.10005 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.02083 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -3.94872 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.89074 |
| DNM1L | dynamin 1-like | -3.78488 |
| TLCD3A | TLC domain containing 3A | -3.75681 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.65561 |
| PCNA | proliferating cell nuclear antigen | -3.38562 |
| GNAS | GNAS complex locus | -3.28055 |
| NGRN | neugrin, neurite outgrowth associated | -3.06914 |
| CCNB2 | cyclin B2 | -3.06781 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.70014 |
| SYNGR3 | synaptogyrin 3 | -2.65451 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.52439 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.44199 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.15817 |
| PTTG1 | pituitary tumor-transforming 1 | -2.14289 |
| TXNDC9 | thioredoxin domain containing 9 | -2.12452 |
| USP6NL | USP6 N-terminal like | -2.06214 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -2.0233 |
