CRCGN010_HEPG2_24H:A24 Gene Set
Genes
47 genes differentially expressed following the CRCGN010_HEPG2_24H:A24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GSTZ1
|
glutathione S-transferase zeta 1
|
5.30033
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.47828
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.38037
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.26718
|
|
EPN2
|
epsin 2
|
4.01785
|
|
CSK
|
c-src tyrosine kinase
|
3.93482
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.89277
|
|
SFTPB
|
surfactant protein B
|
3.79605
|
|
MYLK
|
myosin light chain kinase
|
3.78113
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
3.50962
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.4451
|
|
SATB1
|
SATB homeobox 1
|
3.08535
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.94064
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.82715
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.80124
|
|
GPATCH8
|
G patch domain containing 8
|
2.3357
|
|
PCBD1
|
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
|
2.33567
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.30846
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.17305
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.14143
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.0773
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.07701
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
2.03277
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-9.83719
|
|
CDC20
|
cell division cycle 20
|
-6.0164
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.8548
|
|
LDHD
|
lactate dehydrogenase D
|
-5.55207
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-4.51757
|
|
TLR4
|
toll-like receptor 4
|
-4.26321
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.70471
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.44476
|
|
ZNF586
|
zinc finger protein 586
|
-3.44195
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-3.0155
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.98593
|
|
GNAS
|
GNAS complex locus
|
-2.64305
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.58108
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.573
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.56256
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.51688
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.43139
|
|
ALDH1A1
|
aldehyde dehydrogenase 1 family, member A1
|
-2.37189
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.33821
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.31614
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.23017
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-2.22162
|
|
ISOC1
|
isochorismatase domain containing 1
|
-2.09878
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.03835
|
