| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN010_HEPG2_24H:B03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STK10 | serine/threonine kinase 10 | 7.8375 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.85864 |
| UBQLN2 | ubiquilin 2 | 4.4922 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.46976 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.07685 |
| CHN1 | chimerin 1 | 3.63106 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.61075 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.57188 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 3.38774 |
| MEST | mesoderm specific transcript | 2.94376 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.91606 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.91489 |
| PRKCQ | protein kinase C, theta | 2.78556 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | 2.59893 |
| MAP7 | microtubule-associated protein 7 | 2.4675 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.40547 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.35956 |
| JADE2 | jade family PHD finger 2 | 2.32466 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 2.25285 |
| SGCE | sarcoglycan, epsilon | 2.22171 |
| ZNF143 | zinc finger protein 143 | 2.21402 |
| CHEK2 | checkpoint kinase 2 | 2.16087 |
| ZNF589 | zinc finger protein 589 | 2.12293 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.11857 |
| RPL39L | ribosomal protein L39-like | 2.09938 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.08552 |
| DIPK1A | divergent protein kinase domain 1A | 2.05902 |
| HSPA1A | heat shock 70kDa protein 1A | 2.02534 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC35F2 | solute carrier family 35, member F2 | -5.11037 |
| PCNA | proliferating cell nuclear antigen | -4.72444 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -4.60928 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.24244 |
| NRIP1 | nuclear receptor interacting protein 1 | -4.00681 |
| CHMP4B | charged multivesicular body protein 4B | -3.64563 |
| CD320 | CD320 molecule | -3.478 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.29259 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -3.27302 |
| TP53BP2 | tumor protein p53 binding protein 2 | -3.22572 |
| TLR4 | toll-like receptor 4 | -3.19368 |
| PRPF4 | pre-mRNA processing factor 4 | -3.08294 |
| TGIF1 | TGFB-induced factor homeobox 1 | -2.83719 |
| WASHC4 | WASH complex subunit 4 | -2.72597 |
| FBXO7 | F-box protein 7 | -2.67904 |
| TP53TG5 | TP53 target 5 | -2.50571 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | -2.40755 |
| S100A11 | S100 calcium binding protein A11 | -2.3969 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.3707 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.36804 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -2.26037 |
| MRPL19 | mitochondrial ribosomal protein L19 | -2.21688 |
| RUVBL2 | RuvB-like AAA ATPase 2 | -2.12684 |
| SP3 | Sp3 transcription factor | -2.12449 |
| SLC25A2 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 | -2.11376 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.10913 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -2.10826 |
| RNLS | renalase, FAD-dependent amine oxidase | -2.06158 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.04434 |
| CCDC81 | coiled-coil domain containing 81 | -2.0233 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 | -2.00852 |
