| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | chlorpropamide 39.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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62 genes differentially expressed following the CRCGN010_HEPG2_24H:B07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 | 5.57108 |
| NOTCH1 | notch 1 | 4.84288 |
| UBQLN2 | ubiquilin 2 | 4.56929 |
| ZNF589 | zinc finger protein 589 | 4.5565 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 4.39763 |
| MEST | mesoderm specific transcript | 4.15453 |
| EVL | Enah/Vasp-like | 4.11695 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.02918 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.61082 |
| LCN2 | lipocalin 2 | 3.51681 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.43456 |
| CHMP6 | charged multivesicular body protein 6 | 3.41787 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 3.29335 |
| HOXA10 | homeobox A10 | 3.14014 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.12446 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.902 |
| GPATCH8 | G patch domain containing 8 | 2.75705 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.60798 |
| ORM2 | orosomucoid 2 | 2.55269 |
| ORM1 | orosomucoid 1 | 2.54878 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 2.51283 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 2.46143 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.44548 |
| UFM1 | ubiquitin-fold modifier 1 | 2.30137 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 2.26375 |
| SFTPB | surfactant protein B | 2.22705 |
| SUCLA2 | succinate-CoA ligase, ADP-forming, beta subunit | 2.19379 |
| CYCS | cytochrome c, somatic | 2.16767 |
| PLSCR3 | phospholipid scramblase 3 | 2.15849 |
| TRMT61B | tRNA methyltransferase 61B | 2.158 |
| FPGS | folylpolyglutamate synthase | 2.15063 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.0262 |
| MDN1 | MDN1, midasin homolog (yeast) | 2.02536 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) | 2.00608 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -8.40719 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -7.62492 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -5.34289 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -5.25445 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.81525 |
| TRIB3 | tribbles pseudokinase 3 | -4.77758 |
| LDHD | lactate dehydrogenase D | -4.76944 |
| TLR4 | toll-like receptor 4 | -4.54938 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -4.14996 |
| GNAS | GNAS complex locus | -3.93473 |
| CTSD | cathepsin D | -3.9256 |
| FAIM | Fas apoptotic inhibitory molecule | -3.54876 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.47263 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.40044 |
| RNF167 | ring finger protein 167 | -3.36903 |
| SNX11 | sorting nexin 11 | -3.122 |
| ZNF586 | zinc finger protein 586 | -2.89911 |
| TLCD3A | TLC domain containing 3A | -2.84985 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.7587 |
| HMG20B | high mobility group 20B | -2.55156 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.37248 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.36747 |
| NGRN | neugrin, neurite outgrowth associated | -2.31033 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.20194 |
| PLA2G15 | phospholipase A2, group XV | -2.17447 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | -2.13058 |
| WASHC4 | WASH complex subunit 4 | -2.06517 |
| BANF1 | barrier to autointegration factor 1 | -2.05964 |
