CRCGN010_HEPG2_24H:B08 Gene Set
Genes
51 genes differentially expressed following the CRCGN010_HEPG2_24H:B08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
5.09413
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.04363
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.76394
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.71784
|
|
TXNL4B
|
thioredoxin-like 4B
|
3.67711
|
|
IDE
|
insulin-degrading enzyme
|
3.62105
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
3.61896
|
|
PMM2
|
phosphomannomutase 2
|
3.56138
|
|
PRR15L
|
proline rich 15-like
|
3.5111
|
|
CSK
|
c-src tyrosine kinase
|
3.44478
|
|
MAP7
|
microtubule-associated protein 7
|
3.41619
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.34999
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.2216
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
3.10738
|
|
JADE2
|
jade family PHD finger 2
|
2.74667
|
|
SPTAN1
|
spectrin, alpha, non-erythrocytic 1
|
2.58853
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.57285
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.52044
|
|
CCNF
|
cyclin F
|
2.45096
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.39632
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.35299
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.27637
|
|
TRIM13
|
tripartite motif containing 13
|
2.17619
|
|
CHEK2
|
checkpoint kinase 2
|
2.04771
|
|
WASHC5
|
WASH complex subunit 5
|
2.04122
|
|
SRBD1
|
S1 RNA binding domain 1
|
2.01719
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
VDAC1
|
voltage-dependent anion channel 1
|
-6.22663
|
|
VAT1
|
vesicle amine transport 1
|
-4.748
|
|
GNAS
|
GNAS complex locus
|
-4.37505
|
|
DNM1L
|
dynamin 1-like
|
-4.36567
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.84783
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.81953
|
|
TLR4
|
toll-like receptor 4
|
-3.76316
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.46551
|
|
HMG20B
|
high mobility group 20B
|
-3.21303
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-3.10553
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
-2.99364
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.91416
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.86681
|
|
SCAND1
|
SCAN domain containing 1
|
-2.56866
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.49211
|
|
PLA2G15
|
phospholipase A2, group XV
|
-2.40375
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.26759
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.24029
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
-2.20705
|
|
DDOST
|
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
|
-2.12791
|
|
SPRR1B
|
small proline-rich protein 1B
|
-2.06878
|
|
ZFP30
|
ZFP30 zinc finger protein
|
-2.02544
|
|
GLTP
|
glycolipid transfer protein
|
-2.02227
|
|
ZNF274
|
zinc finger protein 274
|
-2.01827
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.00187
|
