| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | chlorpropamide 9.95 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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76 genes differentially expressed following the CRCGN010_HEPG2_24H:B09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.6488 |
| JADE2 | jade family PHD finger 2 | 5.29366 |
| KLHL21 | kelch-like family member 21 | 5.04514 |
| TATDN2 | TatD DNase domain containing 2 | 5.01936 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.94241 |
| STIMATE | STIM activating enhancer | 4.23179 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.97423 |
| MAP7 | microtubule-associated protein 7 | 3.91061 |
| PRR15L | proline rich 15-like | 3.78038 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.76728 |
| PFKL | phosphofructokinase, liver | 3.57593 |
| GATA3 | GATA binding protein 3 | 3.43309 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.42723 |
| ICAM1 | intercellular adhesion molecule 1 | 3.26153 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.25982 |
| CCNF | cyclin F | 2.87632 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.86806 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.74193 |
| CYCS | cytochrome c, somatic | 2.72056 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 2.6458 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.59169 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.47957 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.47874 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.47685 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 2.47322 |
| CHN1 | chimerin 1 | 2.36067 |
| GPATCH2 | G patch domain containing 2 | 2.30065 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.18044 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.17176 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.14616 |
| GCH1 | GTP cyclohydrolase 1 | 2.0479 |
| DNAJC11 | DnaJ (Hsp40) homolog, subfamily C, member 11 | 2.01694 |
| TEX10 | testis expressed 10 | 2.01549 |
| SLAMF1 | signaling lymphocytic activation molecule family member 1 | 2.00405 |
| MMP3 | matrix metallopeptidase 3 | 2.00211 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -9.02927 |
| CDC25B | cell division cycle 25B | -6.22673 |
| GNAS | GNAS complex locus | -5.89048 |
| LDHD | lactate dehydrogenase D | -5.20728 |
| PCNA | proliferating cell nuclear antigen | -4.74813 |
| THAP11 | THAP domain containing 11 | -4.70112 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.6219 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -4.45869 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.38272 |
| GTPBP8 | GTP-binding protein 8 (putative) | -4.28467 |
| UGDH | UDP-glucose 6-dehydrogenase | -4.21901 |
| TRIB3 | tribbles pseudokinase 3 | -4.1503 |
| SLC35F2 | solute carrier family 35, member F2 | -4.14356 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.02021 |
| CCNB2 | cyclin B2 | -3.77185 |
| WASHC4 | WASH complex subunit 4 | -3.7314 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.61754 |
| LAP3 | leucine aminopeptidase 3 | -3.51253 |
| CCNH | cyclin H | -3.16488 |
| MTFR1 | mitochondrial fission regulator 1 | -2.69398 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | -2.67713 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.59473 |
| SIK2 | salt-inducible kinase 2 | -2.52399 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 | -2.51962 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.47008 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.45681 |
| NARS1 | asparaginyl-tRNA synthetase 1 | -2.43542 |
| PRPF4 | pre-mRNA processing factor 4 | -2.32862 |
| CUEDC2 | CUE domain containing 2 | -2.28025 |
| METTL9 | methyltransferase like 9 | -2.25971 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | -2.24042 |
| RLIM | ring finger protein, LIM domain interacting | -2.21448 |
| POLL | polymerase (DNA directed), lambda | -2.2046 |
| GLB1L | galactosidase, beta 1-like | -2.19232 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.13162 |
| GID8 | GID complex subunit 8 | -2.09343 |
| RBM34 | RNA binding motif protein 34 | -2.07958 |
| SEC61B | Sec61 beta subunit | -2.06695 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -2.05147 |
| RPL36AL | ribosomal protein L36a-like | -2.03065 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.0009 |
