CRCGN010_HEPG2_24H:B10 Gene Set
Genes
49 genes differentially expressed following the CRCGN010_HEPG2_24H:B10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
7.61663
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
6.93266
|
|
UBQLN2
|
ubiquilin 2
|
6.48235
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
6.45663
|
|
EVL
|
Enah/Vasp-like
|
5.78494
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.0237
|
|
SQOR
|
sulfide quinone oxidoreductase
|
4.69612
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
4.20306
|
|
PRR15L
|
proline rich 15-like
|
3.9642
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.85595
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.50275
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.89902
|
|
CYCS
|
cytochrome c, somatic
|
2.78512
|
|
AXIN1
|
axin 1
|
2.62354
|
|
STIMATE
|
STIM activating enhancer
|
2.57652
|
|
CDC45
|
cell division cycle 45
|
2.53247
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.44594
|
|
IFI44L
|
interferon-induced protein 44-like
|
2.35872
|
|
GATA3
|
GATA binding protein 3
|
2.33609
|
|
PIGB
|
phosphatidylinositol glycan anchor biosynthesis, class B
|
2.22665
|
|
CCNF
|
cyclin F
|
2.20222
|
|
RAD51AP1
|
RAD51 associated protein 1
|
2.12286
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.07927
|
|
RBKS
|
ribokinase
|
2.07648
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.0286
|
|
SNX7
|
sorting nexin 7
|
2.02611
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NUP85
|
nucleoporin 85kDa
|
-4.88486
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-4.87405
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.57672
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-4.5032
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.45993
|
|
ZNF586
|
zinc finger protein 586
|
-4.25082
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.57493
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.23065
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.12914
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.9414
|
|
SNX11
|
sorting nexin 11
|
-2.90856
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.82624
|
|
WASHC4
|
WASH complex subunit 4
|
-2.75771
|
|
MRPS7
|
mitochondrial ribosomal protein S7
|
-2.51948
|
|
FBXO7
|
F-box protein 7
|
-2.46221
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.44852
|
|
PAGE4
|
P antigen family, member 4 (prostate associated)
|
-2.24539
|
|
PLK1
|
polo-like kinase 1
|
-2.15887
|
|
ATP6V0B
|
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
|
-2.14072
|
|
CDC20
|
cell division cycle 20
|
-2.11365
|
|
MRPL58
|
mitochondrial ribosomal protein L58
|
-2.07173
|
|
C5
|
complement component 5
|
-2.06279
|
|
GNAS
|
GNAS complex locus
|
-2.00075
|
