| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | indole 20.1 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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61 genes differentially expressed following the CRCGN010_HEPG2_24H:B14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 6.79889 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.30694 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.65364 |
| CNPY3 | canopy FGF signaling regulator 3 | 3.64643 |
| KLHL9 | kelch-like family member 9 | 3.34864 |
| STIMATE | STIM activating enhancer | 3.29977 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.27968 |
| GPATCH8 | G patch domain containing 8 | 3.24954 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.21089 |
| ATP11B | ATPase, class VI, type 11B | 3.09515 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3.09404 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.08311 |
| MVP | major vault protein | 3.06634 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.9281 |
| DENND2D | DENN/MADD domain containing 2D | 2.85445 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 2.81595 |
| TXNRD1 | thioredoxin reductase 1 | 2.65329 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.43387 |
| HSPA8 | heat shock 70kDa protein 8 | 2.43348 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 2.33118 |
| NOSIP | nitric oxide synthase interacting protein | 2.32699 |
| STAT5B | signal transducer and activator of transcription 5B | 2.29771 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.27508 |
| LCN2 | lipocalin 2 | 2.26925 |
| CYCS | cytochrome c, somatic | 2.2123 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.15138 |
| CHMP6 | charged multivesicular body protein 6 | 2.1166 |
| STXBP2 | syntaxin binding protein 2 | 2.09999 |
| SFTPB | surfactant protein B | 2.06323 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.00807 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -6.26145 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.22667 |
| SLC35F2 | solute carrier family 35, member F2 | -5.09444 |
| GNAS | GNAS complex locus | -4.18099 |
| NGRN | neugrin, neurite outgrowth associated | -3.81299 |
| PCNA | proliferating cell nuclear antigen | -3.60194 |
| TUBB6 | tubulin, beta 6 class V | -3.3583 |
| SCAND1 | SCAN domain containing 1 | -3.04001 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.93052 |
| DSG2 | desmoglein 2 | -2.89191 |
| HMG20B | high mobility group 20B | -2.8668 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.80522 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.72631 |
| GDF15 | growth differentiation factor 15 | -2.59454 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.5628 |
| C5 | complement component 5 | -2.55547 |
| TRIB3 | tribbles pseudokinase 3 | -2.5458 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -2.43134 |
| FHL2 | four and a half LIM domains 2 | -2.29263 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.24169 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.22711 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.17648 |
| ZNF586 | zinc finger protein 586 | -2.16302 |
| INTS5 | integrator complex subunit 5 | -2.15529 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.14085 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.10793 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.10316 |
| USP6NL | USP6 N-terminal like | -2.09528 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -2.09197 |
| PCYOX1L | prenylcysteine oxidase 1 like | -2.01543 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -2.01123 |
