CRCGN010_HEPG2_24H:B15 Gene Set
Genes
60 genes differentially expressed following the CRCGN010_HEPG2_24H:B15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
7.23419
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.29667
|
|
RPL39L
|
ribosomal protein L39-like
|
3.99935
|
|
MYLK
|
myosin light chain kinase
|
3.79115
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.75618
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.73971
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.24509
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.21116
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.0145
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.89475
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.72981
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.6579
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.56638
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.52835
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.48733
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.48136
|
|
LCN2
|
lipocalin 2
|
2.43536
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.40496
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.31963
|
|
MAP7
|
microtubule-associated protein 7
|
2.26509
|
|
STAP2
|
signal transducing adaptor family member 2
|
2.24321
|
|
H2BC12
|
H2B clustered histone 12
|
2.19813
|
|
CCNA1
|
cyclin A1
|
2.18382
|
|
MVP
|
major vault protein
|
2.16275
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.13791
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.13125
|
|
VAT1
|
vesicle amine transport 1
|
2.12929
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.01202
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-6.99866
|
|
ZNF586
|
zinc finger protein 586
|
-6.2738
|
|
ADI1
|
acireductone dioxygenase 1
|
-5.01237
|
|
TLR4
|
toll-like receptor 4
|
-4.78343
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-4.27482
|
|
CCNB1
|
cyclin B1
|
-4.01272
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.73002
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.65239
|
|
LDHD
|
lactate dehydrogenase D
|
-3.5699
|
|
SNX11
|
sorting nexin 11
|
-3.54479
|
|
CCNB2
|
cyclin B2
|
-3.44023
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.30214
|
|
DSG2
|
desmoglein 2
|
-3.29475
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.25403
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.22551
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.12928
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.03846
|
|
CTSD
|
cathepsin D
|
-2.94928
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.92148
|
|
RAI14
|
retinoic acid induced 14
|
-2.84125
|
|
SCAND1
|
SCAN domain containing 1
|
-2.80401
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.76102
|
|
NCK1
|
NCK adaptor protein 1
|
-2.65487
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.6351
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-2.59623
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-2.46075
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.33717
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.31342
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.27771
|
|
MACF1
|
microtubule-actin crosslinking factor 1
|
-2.23546
|
|
CAPNS1
|
calpain, small subunit 1
|
-2.22203
|
|
CHST7
|
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
|
-2.07353
|
