CRCGN010_HEPG2_24H:B16 Gene Set
Genes
42 genes differentially expressed following the CRCGN010_HEPG2_24H:B16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
4.11383
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.90295
|
|
MYLK
|
myosin light chain kinase
|
3.80301
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.57179
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.43082
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.18512
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.17611
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.05107
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.02868
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.98498
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.97714
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.57789
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.50842
|
|
CBR3
|
carbonyl reductase 3
|
2.50696
|
|
CCNH
|
cyclin H
|
2.34723
|
|
XKR8
|
XK, Kell blood group complex subunit-related family, member 8
|
2.27792
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.22974
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.2264
|
|
JPT2
|
Jupiter microtubule associated homolog 2
|
2.17427
|
|
FOXRED2
|
FAD-dependent oxidoreductase domain containing 2
|
2.09845
|
|
ZNF589
|
zinc finger protein 589
|
2.08817
|
|
EGF
|
epidermal growth factor
|
2.07047
|
|
CHN1
|
chimerin 1
|
2.05252
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.04735
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-7.19149
|
|
CCNB2
|
cyclin B2
|
-5.72238
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.30519
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.91329
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.4092
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.94505
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.93203
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.85042
|
|
USP6NL
|
USP6 N-terminal like
|
-2.83168
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.46388
|
|
WDR7
|
WD repeat domain 7
|
-2.19657
|
|
CDC20
|
cell division cycle 20
|
-2.13552
|
|
LDHD
|
lactate dehydrogenase D
|
-2.10174
|
|
ZNF587
|
zinc finger protein 587
|
-2.08384
|
|
NCBP2
|
nuclear cap binding protein subunit 2, 20kDa
|
-2.04287
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.04164
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.0256
|
|
PSMD2
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
|
-2.00707
|
