CRCGN010_HEPG2_24H:B18 Gene Set
Genes
54 genes differentially expressed following the CRCGN010_HEPG2_24H:B18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
4.09584
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
3.86897
|
|
INTS3
|
integrator complex subunit 3
|
3.73848
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.49458
|
|
EVL
|
Enah/Vasp-like
|
3.43099
|
|
LCN2
|
lipocalin 2
|
3.41538
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.37842
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.35273
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
3.23888
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.13533
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.01091
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.95301
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.84962
|
|
CSK
|
c-src tyrosine kinase
|
2.70199
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.63135
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.56493
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.52935
|
|
PRR15L
|
proline rich 15-like
|
2.40715
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.31291
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.23931
|
|
CHN1
|
chimerin 1
|
2.22962
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.22462
|
|
WDR7
|
WD repeat domain 7
|
2.20712
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.15748
|
|
BSCL2
|
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
|
2.02859
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.01915
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.63982
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-5.12206
|
|
RPN1
|
ribophorin I
|
-4.26258
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.00595
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.94212
|
|
LDHD
|
lactate dehydrogenase D
|
-3.69849
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.59263
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.57012
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.49824
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.4584
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.38839
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.33427
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.28946
|
|
DSG2
|
desmoglein 2
|
-3.10669
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.92696
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.92155
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.55118
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-2.49189
|
|
PEG10
|
paternally expressed 10
|
-2.46599
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.45001
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.32214
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.3152
|
|
ZNF586
|
zinc finger protein 586
|
-2.2873
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.2438
|
|
CCNB2
|
cyclin B2
|
-2.22843
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.13962
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.09176
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
-2.04474
|
