| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-nitronaphthalene 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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66 genes differentially expressed following the CRCGN010_HEPG2_24H:B19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHMP6 | charged multivesicular body protein 6 | 9.38115 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 7.15213 |
| MYLK | myosin light chain kinase | 5.6381 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 5.5637 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.78409 |
| PRR15L | proline rich 15-like | 4.57062 |
| UBQLN2 | ubiquilin 2 | 4.18277 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.87005 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 3.85951 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 3.80081 |
| MSRA | methionine sulfoxide reductase A | 3.61504 |
| MEST | mesoderm specific transcript | 3.43927 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.11556 |
| STAP2 | signal transducing adaptor family member 2 | 2.87643 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 2.85447 |
| MAP7 | microtubule-associated protein 7 | 2.83099 |
| DIPK1A | divergent protein kinase domain 1A | 2.80442 |
| KLHL21 | kelch-like family member 21 | 2.7911 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.76298 |
| TEX10 | testis expressed 10 | 2.7351 |
| GAA | glucosidase, alpha; acid | 2.55134 |
| PNKP | polynucleotide kinase 3'-phosphatase | 2.52327 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.49977 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | 2.25473 |
| FGL2 | fibrinogen-like 2 | 2.18996 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 | 2.17102 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.15928 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.15603 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.15558 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.1329 |
| MMP1 | matrix metallopeptidase 1 | 2.13157 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.10947 |
| PLXNC1 | plexin C1 | 2.10898 |
| FMO1 | flavin containing monooxygenase 1 | 2.08346 |
| LOC122526780 | uncharacterized LOC122526780 | 2.07538 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 2.03347 |
| EGF | epidermal growth factor | 2.02964 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -9.95033 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.60497 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.49732 |
| TP53BP2 | tumor protein p53 binding protein 2 | -4.48765 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -4.23088 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.97246 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.76144 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.29411 |
| UBE3C | ubiquitin protein ligase E3C | -3.21955 |
| GNAS | GNAS complex locus | -3.05913 |
| LDHD | lactate dehydrogenase D | -3.0434 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.02262 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.98613 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.92807 |
| DNM1L | dynamin 1-like | -2.88945 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.72822 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.68371 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -2.60343 |
| SLC35F2 | solute carrier family 35, member F2 | -2.5269 |
| NGRN | neugrin, neurite outgrowth associated | -2.43822 |
| WASHC4 | WASH complex subunit 4 | -2.43525 |
| TLCD3A | TLC domain containing 3A | -2.43377 |
| UXS1 | UDP-glucuronate decarboxylase 1 | -2.32022 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.23696 |
| PCNA | proliferating cell nuclear antigen | -2.22136 |
| RPIA | ribose 5-phosphate isomerase A | -2.18176 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.17633 |
| SOAT2 | sterol O-acyltransferase 2 | -2.12469 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -2.04851 |
