| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-nitronaphthalene 10.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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80 genes differentially expressed following the CRCGN010_HEPG2_24H:B21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 8.28508 |
| CYCS | cytochrome c, somatic | 6.63226 |
| CBR3 | carbonyl reductase 3 | 6.29875 |
| LCN2 | lipocalin 2 | 6.05797 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 5.98215 |
| MAMLD1 | mastermind-like domain containing 1 | 5.37256 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.14835 |
| HOXA10 | homeobox A10 | 4.73045 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.26183 |
| EPN2 | epsin 2 | 3.58815 |
| KLHL9 | kelch-like family member 9 | 3.25081 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 3.19675 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 3.09868 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.06208 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.92551 |
| MCM3 | minichromosome maintenance complex component 3 | 2.88666 |
| PRR15L | proline rich 15-like | 2.86334 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.83576 |
| TXNL4B | thioredoxin-like 4B | 2.79535 |
| BAD | BCL2-associated agonist of cell death | 2.68398 |
| HOXA10-HOXA9 | HOXA10-HOXA9 readthrough | 2.67484 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.62602 |
| CDK4 | cyclin-dependent kinase 4 | 2.5878 |
| NKX2-2 | NK2 homeobox 2 | 2.46042 |
| MB | myoglobin | 2.36704 |
| HBB | hemoglobin, beta | 2.34971 |
| ZFP36 | ZFP36 ring finger protein | 2.30931 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A | 2.22233 |
| HBA1 | hemoglobin, alpha 1 | 2.20542 |
| MATN2 | matrilin 2 | 2.15547 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 | 2.14116 |
| ECM1 | extracellular matrix protein 1 | 2.13224 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.12052 |
| HOXA11 | homeobox A11 | 2.10559 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.10525 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 2.08946 |
| TLE2 | transducin-like enhancer of split 2 | 2.08522 |
| LOC102724594 | splicing factor U2AF 35 kDa subunit | 2.01298 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | 2.00873 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.00622 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -7.67521 |
| TLR4 | toll-like receptor 4 | -6.86888 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.62638 |
| CCDC86 | coiled-coil domain containing 86 | -5.22935 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -4.97473 |
| LAP3 | leucine aminopeptidase 3 | -4.87796 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.66275 |
| VAT1 | vesicle amine transport 1 | -4.24487 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -4.14263 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -4.09533 |
| RNF167 | ring finger protein 167 | -3.8784 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.81062 |
| TRIB3 | tribbles pseudokinase 3 | -3.74823 |
| DSG2 | desmoglein 2 | -3.66258 |
| EBNA1BP2 | EBNA1 binding protein 2 | -3.53047 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.5276 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.22121 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.85175 |
| TWF2 | twinfilin actin binding protein 2 | -2.75643 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.62534 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 | -2.54547 |
| TLCD3A | TLC domain containing 3A | -2.37798 |
| STXBP1 | syntaxin binding protein 1 | -2.33486 |
| GNAS | GNAS complex locus | -2.31906 |
| MGA | MGA, MAX dimerization protein | -2.27477 |
| PPOX | protoporphyrinogen oxidase | -2.26621 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.23536 |
| EIF2B4 | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | -2.20301 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | -2.1572 |
| CUTA | cutA divalent cation tolerance homolog (E. coli) | -2.15284 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.1314 |
| GMIP | GEM interacting protein | -2.11239 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.10145 |
| GRK3 | G protein-coupled receptor kinase 3 | -2.07354 |
| CPNE7 | copine VII | -2.04142 |
| ZNF813 | zinc finger protein 813 | -2.0346 |
| OCEL1 | occludin/ELL domain containing 1 | -2.03145 |
| TMC5 | transmembrane channel-like 5 | -2.02279 |
| SMYD2 | SET and MYND domain containing 2 | -2.02053 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -2.01105 |
