| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-nitronaphthalene 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN010_HEPG2_24H:B22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NOTCH1 | notch 1 | 7.21435 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 6.0304 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.78878 |
| UBQLN2 | ubiquilin 2 | 4.63748 |
| CHN1 | chimerin 1 | 4.62214 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 4.61627 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.4318 |
| NMU | neuromedin U | 4.28996 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 4.0084 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.86877 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.75231 |
| MCM3 | minichromosome maintenance complex component 3 | 3.51735 |
| SFTPB | surfactant protein B | 3.45867 |
| PFKL | phosphofructokinase, liver | 3.05648 |
| TXNL4B | thioredoxin-like 4B | 2.91053 |
| ZNF589 | zinc finger protein 589 | 2.77735 |
| PKN1 | protein kinase N1 | 2.69047 |
| AXIN1 | axin 1 | 2.66083 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.64352 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.52298 |
| JADE2 | jade family PHD finger 2 | 2.49511 |
| ATP11B | ATPase, class VI, type 11B | 2.41742 |
| MOK | MOK protein kinase | 2.39735 |
| PLD3 | phospholipase D family, member 3 | 2.38303 |
| HOXA10 | homeobox A10 | 2.31519 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.28288 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 2.16178 |
| LCN2 | lipocalin 2 | 2.07617 |
| HOOK2 | hook microtubule-tethering protein 2 | 2.06361 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.0458 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 2.04546 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.04156 |
| PFKP | phosphofructokinase, platelet | 2.0013 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -7.04325 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.38743 |
| ZNF586 | zinc finger protein 586 | -5.88605 |
| LAP3 | leucine aminopeptidase 3 | -5.26614 |
| TRIB3 | tribbles pseudokinase 3 | -5.20795 |
| CCDC86 | coiled-coil domain containing 86 | -4.9686 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -4.85618 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.71572 |
| LDHD | lactate dehydrogenase D | -4.65157 |
| ADI1 | acireductone dioxygenase 1 | -4.29484 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -4.07042 |
| CHMP4B | charged multivesicular body protein 4B | -3.8637 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -3.7356 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.53307 |
| RAI14 | retinoic acid induced 14 | -2.67544 |
| GLOD4 | glyoxalase domain containing 4 | -2.58411 |
| CD320 | CD320 molecule | -2.47427 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -2.3686 |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) | -2.3547 |
| SPA17 | sperm autoantigenic protein 17 | -2.23457 |
| MED28 | mediator complex subunit 28 | -2.23067 |
| NBR1 | neighbor of BRCA1 gene 1 | -2.16537 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.13718 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | -2.04148 |
| MRFAP1L1 | Morf4 family associated protein 1-like 1 | -2.0399 |
| SPAG4 | sperm associated antigen 4 | -2.03673 |
