CRCGN010_HEPG2_24H:B24 Gene Set
Genes
61 genes differentially expressed following the CRCGN010_HEPG2_24H:B24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PRR15L
|
proline rich 15-like
|
5.70183
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.87957
|
|
CYCS
|
cytochrome c, somatic
|
4.09638
|
|
MAP7
|
microtubule-associated protein 7
|
3.99762
|
|
SFTPB
|
surfactant protein B
|
3.97388
|
|
IDE
|
insulin-degrading enzyme
|
3.78175
|
|
E2F2
|
E2F transcription factor 2
|
3.68388
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.62486
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
3.49925
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.47743
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.40294
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.92868
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.82148
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.53251
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.35189
|
|
CPTP
|
ceramide-1-phosphate transfer protein
|
2.30931
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.22332
|
|
ZNF589
|
zinc finger protein 589
|
2.17961
|
|
ODR4
|
odr-4 GPCR localization factor homolog
|
2.10304
|
|
INTS11
|
integrator complex subunit 11
|
2.09529
|
|
TBC1D9B
|
TBC1 domain family, member 9B (with GRAM domain)
|
2.07984
|
|
TEX10
|
testis expressed 10
|
2.0713
|
|
ECD
|
ecdysoneless homolog (Drosophila)
|
2.05263
|
|
CDSN
|
corneodesmosin
|
2.03543
|
|
STAG3
|
stromal antigen 3
|
2.023
|
|
NKX2-1
|
NK2 homeobox 1
|
2.00697
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-9.09002
|
|
ZNF586
|
zinc finger protein 586
|
-8.81717
|
|
CDC20
|
cell division cycle 20
|
-5.13861
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.03746
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-5.00526
|
|
PEG10
|
paternally expressed 10
|
-5.0
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-4.2701
|
|
TLR4
|
toll-like receptor 4
|
-4.16012
|
|
GNAS
|
GNAS complex locus
|
-4.07029
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.02526
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.54967
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.49425
|
|
SCRIB
|
scribbled planar cell polarity protein
|
-2.62196
|
|
RNF167
|
ring finger protein 167
|
-2.60596
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.51049
|
|
ZNF7
|
zinc finger protein 7
|
-2.38714
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.38654
|
|
CYP2R1
|
cytochrome P450, family 2, subfamily R, polypeptide 1
|
-2.33707
|
|
CYRIB
|
CYFIP related Rac1 interactor B
|
-2.33588
|
|
MAGEC2
|
melanoma antigen family C2
|
-2.24175
|
|
CD247
|
CD247 molecule
|
-2.2413
|
|
ARID5A
|
AT rich interactive domain 5A (MRF1-like)
|
-2.2411
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.22061
|
|
ZNF134
|
zinc finger protein 134
|
-2.19269
|
|
PADI2
|
peptidyl arginine deiminase, type II
|
-2.17875
|
|
CRYAB
|
crystallin, alpha B
|
-2.14925
|
|
ZNF562
|
zinc finger protein 562
|
-2.13557
|
|
PCDHGA8
|
protocadherin gamma subfamily A, 8
|
-2.12428
|
|
SCIN
|
scinderin
|
-2.11507
|
|
LPL
|
lipoprotein lipase
|
-2.1004
|
|
RBMY1J
|
RNA binding motif protein, Y-linked, family 1, member J
|
-2.09558
|
|
ZNF197
|
zinc finger protein 197
|
-2.06948
|
|
OLFML2A
|
olfactomedin-like 2A
|
-2.05755
|
|
MFGE8
|
milk fat globule-EGF factor 8 protein
|
-2.02949
|
|
ZNF34
|
zinc finger protein 34
|
-2.0262
|
