| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tert-butylhydroquinone 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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100 genes differentially expressed following the CRCGN010_HEPG2_24H:C02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 9.37527 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.74039 |
| LCN2 | lipocalin 2 | 6.34943 |
| EPHB2 | EPH receptor B2 | 5.89993 |
| ABHD4 | abhydrolase domain containing 4 | 5.71037 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 5.50376 |
| CBR3 | carbonyl reductase 3 | 5.03369 |
| UGDH | UDP-glucose 6-dehydrogenase | 5.00397 |
| KEAP1 | kelch-like ECH-associated protein 1 | 4.9973 |
| CTSL | cathepsin L | 4.55357 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.29734 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.04287 |
| TEX10 | testis expressed 10 | 3.94958 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.74108 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 3.6513 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.61657 |
| UBQLN2 | ubiquilin 2 | 3.57528 |
| SQSTM1 | sequestosome 1 | 3.41274 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 3.35895 |
| RRAGA | Ras-related GTP binding A | 3.29407 |
| TXNL4B | thioredoxin-like 4B | 3.16955 |
| MYLK | myosin light chain kinase | 3.10257 |
| BLMH | bleomycin hydrolase | 3.10041 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3.05376 |
| EPHA3 | EPH receptor A3 | 3.03929 |
| PLS1 | plastin 1 | 2.99508 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.91434 |
| HOXA10 | homeobox A10 | 2.88782 |
| STIMATE | STIM activating enhancer | 2.79014 |
| CSK | c-src tyrosine kinase | 2.77847 |
| MAP7 | microtubule-associated protein 7 | 2.68981 |
| BZW2 | basic leucine zipper and W2 domains 2 | 2.54285 |
| CYCS | cytochrome c, somatic | 2.48419 |
| FOSL1 | FOS-like antigen 1 | 2.46222 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 2.44226 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.41901 |
| TATDN2 | TatD DNase domain containing 2 | 2.3926 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.38619 |
| PODXL2 | podocalyxin-like 2 | 2.32745 |
| CCL24 | chemokine (C-C motif) ligand 24 | 2.30826 |
| CBR1 | carbonyl reductase 1 | 2.30385 |
| STXBP2 | syntaxin binding protein 2 | 2.28023 |
| E2F2 | E2F transcription factor 2 | 2.26298 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 2.25374 |
| TBP | TATA box binding protein | 2.23543 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.20374 |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) | 2.16572 |
| MRPS2 | mitochondrial ribosomal protein S2 | 2.1541 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | 2.14074 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 | 2.13364 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 2.09687 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 | 2.0869 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 2.05991 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.05836 |
| HMOX1 | heme oxygenase 1 | 2.05106 |
| TKT | transketolase | 2.04873 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.01629 |
| SLC28A3 | solute carrier family 28 (concentrative nucleoside transporter), member 3 | 2.00253 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PEG10 | paternally expressed 10 | -6.62016 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.19862 |
| CHMP4B | charged multivesicular body protein 4B | -5.51711 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.03149 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -4.65209 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -4.39287 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.23185 |
| GOLT1B | golgi transport 1B | -3.98243 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -3.94176 |
| LDHD | lactate dehydrogenase D | -3.92315 |
| TRIB3 | tribbles pseudokinase 3 | -3.78564 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.74701 |
| SNX11 | sorting nexin 11 | -3.53186 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.35417 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -3.34991 |
| PCNA | proliferating cell nuclear antigen | -3.08519 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -2.93514 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.89992 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.89972 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -2.7231 |
| ZNF586 | zinc finger protein 586 | -2.6943 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.63008 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.54585 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.53089 |
| MYL9 | myosin, light chain 9, regulatory | -2.52075 |
| TSPAN4 | tetraspanin 4 | -2.50541 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -2.46512 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.44156 |
| RPS5 | ribosomal protein S5 | -2.35038 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -2.31016 |
| KLK5 | kallikrein-related peptidase 5 | -2.27468 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.25691 |
| GLDC | glycine dehydrogenase (decarboxylating) | -2.21327 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.20539 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -2.17704 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.17347 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.16828 |
| MAGT1 | magnesium transporter 1 | -2.16337 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.10976 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.09131 |
| PRPF4 | pre-mRNA processing factor 4 | -2.08883 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.07155 |
