| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tert-butylhydroquinone 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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72 genes differentially expressed following the CRCGN010_HEPG2_24H:C04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 8.51462 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 6.75347 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 6.72678 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 6.03969 |
| TXNRD1 | thioredoxin reductase 1 | 4.5331 |
| GPATCH8 | G patch domain containing 8 | 3.58616 |
| CCL2 | chemokine (C-C motif) ligand 2 | 3.58572 |
| PNKP | polynucleotide kinase 3'-phosphatase | 3.43299 |
| CHMP6 | charged multivesicular body protein 6 | 3.31389 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.25774 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 3.11193 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.10543 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.86336 |
| HSPA1A | heat shock 70kDa protein 1A | 2.84455 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.8405 |
| BLMH | bleomycin hydrolase | 2.75583 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.71157 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.58932 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.57246 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.40282 |
| DIPK1A | divergent protein kinase domain 1A | 2.38212 |
| PPIH | peptidylprolyl isomerase H (cyclophilin H) | 2.32772 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.25055 |
| PMM2 | phosphomannomutase 2 | 2.20256 |
| SFTPB | surfactant protein B | 2.16783 |
| CYCS | cytochrome c, somatic | 2.16361 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.1367 |
| ABHD4 | abhydrolase domain containing 4 | 2.12023 |
| NOSIP | nitric oxide synthase interacting protein | 2.06574 |
| FOSL1 | FOS-like antigen 1 | 2.05971 |
| MMP1 | matrix metallopeptidase 1 | 2.04497 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 2.03342 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.00804 |
| RLN1 | relaxin 1 | 2.00121 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -6.70506 |
| LDHD | lactate dehydrogenase D | -6.68511 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -6.05561 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.81908 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -5.38153 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -4.5194 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.45444 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -3.92496 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -3.7189 |
| TLR4 | toll-like receptor 4 | -3.5176 |
| CDC20 | cell division cycle 20 | -3.32447 |
| CCDC86 | coiled-coil domain containing 86 | -3.07127 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.00333 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.90873 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.77587 |
| ADI1 | acireductone dioxygenase 1 | -2.75873 |
| TSPAN4 | tetraspanin 4 | -2.70784 |
| PLK1 | polo-like kinase 1 | -2.66857 |
| CCNB2 | cyclin B2 | -2.65042 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.63415 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.58078 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.54157 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.43131 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.40892 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.38121 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.33268 |
| CHMP4B | charged multivesicular body protein 4B | -2.29411 |
| YME1L1 | YME1-like 1 ATPase | -2.26073 |
| SNX11 | sorting nexin 11 | -2.20816 |
| CAB39 | calcium binding protein 39 | -2.19172 |
| NOTCH2NLB | notch 2 N-terminal like B | -2.15175 |
| CD180 | CD180 molecule | -2.13141 |
| DENND2A | DENN/MADD domain containing 2A | -2.10467 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.09083 |
| SNAP91 | synaptosomal-associated protein, 91kDa | -2.09037 |
| CETP | cholesteryl ester transfer protein, plasma | -2.07757 |
| KLRC4-KLRK1 | KLRC4-KLRK1 readthrough | -2.05943 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.03573 |
