CRCGN010_HEPG2_24H:C05 Gene Set
Genes
44 genes differentially expressed following the CRCGN010_HEPG2_24H:C05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CCL2
|
chemokine (C-C motif) ligand 2
|
5.3689
|
|
NMU
|
neuromedin U
|
5.14098
|
|
GATA3
|
GATA binding protein 3
|
3.86628
|
|
STIMATE
|
STIM activating enhancer
|
3.82132
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.77314
|
|
CHN1
|
chimerin 1
|
3.38537
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.35884
|
|
NUP133
|
nucleoporin 133kDa
|
3.16228
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.13937
|
|
PMM2
|
phosphomannomutase 2
|
3.10867
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.90588
|
|
JADE2
|
jade family PHD finger 2
|
2.90456
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.65241
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.61607
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.60746
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.58107
|
|
TXNRD1
|
thioredoxin reductase 1
|
2.57882
|
|
VGLL4
|
vestigial-like family member 4
|
2.56548
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.55661
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.50631
|
|
CCNF
|
cyclin F
|
2.50616
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.37483
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.31022
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.15954
|
|
CTSL
|
cathepsin L
|
2.1465
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.13692
|
|
TRIM13
|
tripartite motif containing 13
|
2.13086
|
|
KLRB1
|
killer cell lectin-like receptor subfamily B, member 1
|
2.05819
|
|
PRR15L
|
proline rich 15-like
|
2.01438
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-8.1171
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-6.65494
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-6.08917
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-6.07211
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.96916
|
|
VAT1
|
vesicle amine transport 1
|
-5.66911
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.36285
|
|
TCTN1
|
tectonic family member 1
|
-3.16328
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.12612
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.86262
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.83847
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.74422
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.54654
|
|
GAL3ST1
|
galactose-3-O-sulfotransferase 1
|
-2.27335
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.22584
|