CRCGN010_HEPG2_24H:C09 Gene Set
Genes
54 genes differentially expressed following the CRCGN010_HEPG2_24H:C09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
10.0
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
5.50134
|
|
EVL
|
Enah/Vasp-like
|
4.50075
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.32328
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.79282
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.68612
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.67395
|
|
E2F2
|
E2F transcription factor 2
|
3.60683
|
|
ZNF589
|
zinc finger protein 589
|
3.28641
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.19883
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.15389
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.0884
|
|
UBQLN2
|
ubiquilin 2
|
3.01706
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.79509
|
|
CHN1
|
chimerin 1
|
2.69404
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.68731
|
|
FPGS
|
folylpolyglutamate synthase
|
2.66569
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.61798
|
|
SATB1
|
SATB homeobox 1
|
2.53349
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.48159
|
|
HOXA10
|
homeobox A10
|
2.46551
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.34666
|
|
EGF
|
epidermal growth factor
|
2.31423
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
2.31145
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.23455
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.18812
|
|
GAL3ST4
|
galactose-3-O-sulfotransferase 4
|
2.07398
|
|
SLC75A1
|
solute carrier family 75 member 1
|
2.06708
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-6.39039
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.26967
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.09012
|
|
PLK1
|
polo-like kinase 1
|
-3.76152
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.73926
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.72717
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.62208
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.45279
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.34055
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.12056
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.85567
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.79747
|
|
WASHC4
|
WASH complex subunit 4
|
-2.48466
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.47351
|
|
PEG10
|
paternally expressed 10
|
-2.45292
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.37427
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.33245
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.24726
|
|
SCGB2A2
|
secretoglobin, family 2A, member 2
|
-2.22299
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.1895
|
|
SNX11
|
sorting nexin 11
|
-2.13707
|
|
CTSD
|
cathepsin D
|
-2.13641
|
|
CCNB1
|
cyclin B1
|
-2.08628
|
|
GNAS
|
GNAS complex locus
|
-2.06705
|
|
RPS5
|
ribosomal protein S5
|
-2.04153
|
|
CAB39
|
calcium binding protein 39
|
-2.02962
|
