CRCGN010_HEPG2_24H:C10 Gene Set
Genes
42 genes differentially expressed following the CRCGN010_HEPG2_24H:C10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
3.72916
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.60976
|
|
CSK
|
c-src tyrosine kinase
|
3.5758
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
3.31348
|
|
AXIN1
|
axin 1
|
3.20244
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.12657
|
|
CCNF
|
cyclin F
|
3.12599
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.00199
|
|
CHN1
|
chimerin 1
|
2.90973
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.84233
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.80069
|
|
PRKCH
|
protein kinase C, eta
|
2.75893
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.6427
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.58438
|
|
MAP7
|
microtubule-associated protein 7
|
2.55347
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.49682
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.47651
|
|
PFKL
|
phosphofructokinase, liver
|
2.3692
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.35782
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
2.30291
|
|
LCN2
|
lipocalin 2
|
2.17104
|
|
STXBP2
|
syntaxin binding protein 2
|
2.15529
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.78422
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.37242
|
|
RNF167
|
ring finger protein 167
|
-4.05226
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.91237
|
|
CCNB2
|
cyclin B2
|
-3.66685
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.47334
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.32923
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.32381
|
|
LDHD
|
lactate dehydrogenase D
|
-3.18401
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.9562
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.90809
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.79186
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.41682
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.37183
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-2.25657
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-2.21006
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.16192
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.15053
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.1335
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.04605
|
