| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-phenyl-2-thiourea 1.27 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
59 genes differentially expressed following the CRCGN010_HEPG2_24H:C12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 8.12905 |
| MAP7 | microtubule-associated protein 7 | 6.8509 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.77933 |
| CSK | c-src tyrosine kinase | 4.49751 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.35974 |
| STAP2 | signal transducing adaptor family member 2 | 4.27545 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.14429 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.12374 |
| CBR3 | carbonyl reductase 3 | 3.97149 |
| MAMLD1 | mastermind-like domain containing 1 | 3.89412 |
| ADRB2 | adrenoceptor beta 2, surface | 3.83404 |
| UBQLN2 | ubiquilin 2 | 3.72598 |
| TATDN2 | TatD DNase domain containing 2 | 3.55711 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.44829 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 3.38095 |
| E2F2 | E2F transcription factor 2 | 3.37538 |
| ABHD6 | abhydrolase domain containing 6 | 3.31408 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.17253 |
| RAB21 | RAB21, member RAS oncogene family | 2.91675 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.86993 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.75389 |
| UFM1 | ubiquitin-fold modifier 1 | 2.57316 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.52337 |
| DIPK1A | divergent protein kinase domain 1A | 2.41818 |
| PRR15L | proline rich 15-like | 2.24398 |
| ZFP36 | ZFP36 ring finger protein | 2.22956 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.09529 |
| RAB43 | RAB43, member RAS oncogene family | 2.00431 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -6.31912 |
| TLCD3A | TLC domain containing 3A | -5.49187 |
| PCNA | proliferating cell nuclear antigen | -4.32591 |
| COG7 | component of oligomeric golgi complex 7 | -4.07338 |
| NRIP1 | nuclear receptor interacting protein 1 | -4.03871 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.0252 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.93855 |
| DSG2 | desmoglein 2 | -3.77355 |
| MRPS16 | mitochondrial ribosomal protein S16 | -3.54015 |
| CD58 | CD58 molecule | -3.5002 |
| FAIM | Fas apoptotic inhibitory molecule | -3.46992 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.39353 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -3.27539 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.11116 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.09956 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.09319 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -3.05602 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.00452 |
| GNAS | GNAS complex locus | -2.98567 |
| RPIA | ribose 5-phosphate isomerase A | -2.93216 |
| ADI1 | acireductone dioxygenase 1 | -2.87182 |
| TRIB3 | tribbles pseudokinase 3 | -2.58059 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.39784 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.33389 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.31122 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -2.29331 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.21292 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.13123 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 | -2.08534 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.06883 |
| CDC25B | cell division cycle 25B | -2.03112 |
