| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methylethylketoxime 19.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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67 genes differentially expressed following the CRCGN010_HEPG2_24H:C14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHMP6 | charged multivesicular body protein 6 | 9.63184 |
| MAP7 | microtubule-associated protein 7 | 5.45511 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 5.3719 |
| CCDC92 | coiled-coil domain containing 92 | 5.15718 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 5.10985 |
| FOXO4 | forkhead box O4 | 5.09097 |
| ATP11B | ATPase, class VI, type 11B | 4.88561 |
| CBR3 | carbonyl reductase 3 | 3.86736 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.69942 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.47108 |
| EGF | epidermal growth factor | 3.39239 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 | 3.2453 |
| MAMLD1 | mastermind-like domain containing 1 | 3.21646 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.05986 |
| CYCS | cytochrome c, somatic | 2.98589 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.95549 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.94526 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.85542 |
| CHN1 | chimerin 1 | 2.57916 |
| NLGN3 | neuroligin 3 | 2.40239 |
| FAM110D | family with sequence similarity 110, member D | 2.36568 |
| TCF15 | transcription factor 15 (basic helix-loop-helix) | 2.35791 |
| JADE2 | jade family PHD finger 2 | 2.35424 |
| HSPA8 | heat shock 70kDa protein 8 | 2.27879 |
| CYP2A13 | cytochrome P450, family 2, subfamily A, polypeptide 13 | 2.24998 |
| DKKL1 | dickkopf-like 1 | 2.23798 |
| ZNF646 | zinc finger protein 646 | 2.21911 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 | 2.19023 |
| MYOG | myogenin (myogenic factor 4) | 2.18994 |
| HOXB3 | homeobox B3 | 2.16531 |
| ABHD6 | abhydrolase domain containing 6 | 2.16505 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.11626 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.11432 |
| INTS3 | integrator complex subunit 3 | 2.09046 |
| PMM2 | phosphomannomutase 2 | 2.03822 |
| RCE1 | Ras converting CAAX endopeptidase 1 | 2.03681 |
| CLCC1 | chloride channel CLIC-like 1 | 2.03418 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) | 2.02242 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -8.54934 |
| ELAC2 | elaC ribonuclease Z 2 | -5.39251 |
| COG2 | component of oligomeric golgi complex 2 | -5.07154 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -5.04212 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.73736 |
| DSG2 | desmoglein 2 | -4.51055 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.39836 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.17735 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -3.96098 |
| CDC20 | cell division cycle 20 | -3.85614 |
| ZNF586 | zinc finger protein 586 | -3.57321 |
| TSPAN4 | tetraspanin 4 | -3.31183 |
| CCNB1 | cyclin B1 | -3.1657 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -3.16002 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.00387 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.98435 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.81373 |
| GDF15 | growth differentiation factor 15 | -2.67608 |
| TLCD3A | TLC domain containing 3A | -2.67114 |
| TLR4 | toll-like receptor 4 | -2.60645 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.45445 |
| HSPB11 | heat shock protein family B (small), member 11 | -2.42396 |
| GNAS | GNAS complex locus | -2.34904 |
| MLPH | melanophilin | -2.3163 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.23286 |
| NGRN | neugrin, neurite outgrowth associated | -2.18607 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.07852 |
| HAT1 | histone acetyltransferase 1 | -2.04806 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.00277 |
