| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methylethylketoxime 4.95 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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60 genes differentially expressed following the CRCGN010_HEPG2_24H:C16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAMLD1 | mastermind-like domain containing 1 | 5.75811 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.85118 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.79992 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.5368 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.42229 |
| STIMATE | STIM activating enhancer | 4.35792 |
| CHMP6 | charged multivesicular body protein 6 | 4.261 |
| UBQLN2 | ubiquilin 2 | 4.15993 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.97682 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.64737 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3.59935 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.52173 |
| IDE | insulin-degrading enzyme | 3.43004 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.1487 |
| FZD7 | frizzled class receptor 7 | 3.01343 |
| PRR15L | proline rich 15-like | 2.92596 |
| ABHD6 | abhydrolase domain containing 6 | 2.92384 |
| NOSIP | nitric oxide synthase interacting protein | 2.91796 |
| LOC122526780 | uncharacterized LOC122526780 | 2.90994 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.77853 |
| SMAD3 | SMAD family member 3 | 2.77103 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.7635 |
| CDC45 | cell division cycle 45 | 2.67741 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.47306 |
| CCNF | cyclin F | 2.46821 |
| CHN1 | chimerin 1 | 2.45254 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.33545 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 2.32642 |
| CYCS | cytochrome c, somatic | 2.30427 |
| COX8A | cytochrome c oxidase subunit VIIIA (ubiquitous) | 2.25263 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 2.19017 |
| MEST | mesoderm specific transcript | 2.19006 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.1064 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -6.16116 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -5.26863 |
| TUBB6 | tubulin, beta 6 class V | -5.03855 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.73504 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.69221 |
| FAIM | Fas apoptotic inhibitory molecule | -4.6423 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.57642 |
| CAB39 | calcium binding protein 39 | -4.49337 |
| CDC20 | cell division cycle 20 | -4.49281 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.42556 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.39761 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -3.9029 |
| RNF167 | ring finger protein 167 | -3.77274 |
| YME1L1 | YME1-like 1 ATPase | -3.32009 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.91435 |
| TCTN1 | tectonic family member 1 | -2.79358 |
| PEG10 | paternally expressed 10 | -2.77785 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.43315 |
| PPOX | protoporphyrinogen oxidase | -2.38881 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.31467 |
| GNAS | GNAS complex locus | -2.29562 |
| NGRN | neugrin, neurite outgrowth associated | -2.24999 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | -2.19108 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | -2.15121 |
| C5 | complement component 5 | -2.14354 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 | -2.06013 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.03984 |
