CRCGN010_HEPG2_24H:C19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description mitoxantrone 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1443 genes differentially expressed following the CRCGN010_HEPG2_24H:C19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HEBP1 heme binding protein 1 9.7804
RPP38 ribonuclease P/MRP 38kDa subunit 9.68928
MEST mesoderm specific transcript 8.55578
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 8.55026
PPP1R13B protein phosphatase 1, regulatory subunit 13B 7.71612
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 7.67841
TENT4A terminal nucleotidyltransferase 4A 7.5851
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 7.40494
MSRA methionine sulfoxide reductase A 7.25194
UBE2L6 ubiquitin-conjugating enzyme E2L 6 7.20256
TIMP2 TIMP metallopeptidase inhibitor 2 6.57791
CCDC85B coiled-coil domain containing 85B 6.344
BZW2 basic leucine zipper and W2 domains 2 6.34042
TRAPPC6A trafficking protein particle complex 6A 6.15706
IFNAR1 interferon (alpha, beta and omega) receptor 1 6.04907
TGFB3 transforming growth factor, beta 3 6.03847
NOTCH1 notch 1 5.83692
ATP11B ATPase, class VI, type 11B 5.8349
CTSD cathepsin D 5.81084
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 5.80122
ARL4C ADP-ribosylation factor-like 4C 5.76455
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 5.7536
EDN1 endothelin 1 5.58326
IL1B interleukin 1, beta 5.52814
TERT telomerase reverse transcriptase 5.50246
HTRA1 HtrA serine peptidase 1 5.3588
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 5.30576
NMU neuromedin U 5.23898
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 5.1682
ARHGAP8 Rho GTPase activating protein 8 5.14884
PRKX protein kinase, X-linked 5.12336
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 5.08788
TMEM109 transmembrane protein 109 5.08238
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 5.06295
AMDHD2 amidohydrolase domain containing 2 4.93369
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 4.87313
CIAO3 cytosolic iron-sulfur assembly component 3 4.87224
LSR lipolysis stimulated lipoprotein receptor 4.82732
RTL8A retrotransposon Gag like 8A 4.75382
MYL9 myosin, light chain 9, regulatory 4.71742
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 4.70864
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 4.66798
SQOR sulfide quinone oxidoreductase 4.63847
FCHO1 FCH domain only 1 4.63368
UBQLN2 ubiquilin 2 4.61998
GPC1 glypican 1 4.61874
RAB21 RAB21, member RAS oncogene family 4.6172
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 4.58519
BAD BCL2-associated agonist of cell death 4.55451
TCEA2 transcription elongation factor A (SII), 2 4.53626
NR1H2 nuclear receptor subfamily 1, group H, member 2 4.48185
CCNA1 cyclin A1 4.47741
TP53 tumor protein p53 4.45019
H2BC21 H2B clustered histone 21 4.34868
SH3D19 SH3 domain containing 19 4.33742
ABHD4 abhydrolase domain containing 4 4.32774
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 4.3265
CDC45 cell division cycle 45 4.26824
PPIE peptidylprolyl isomerase E (cyclophilin E) 4.25993
SOCS2 suppressor of cytokine signaling 2 4.22862
LPAR2 lysophosphatidic acid receptor 2 4.22701
PTPRK protein tyrosine phosphatase, receptor type, K 4.19499
LPAR3 lysophosphatidic acid receptor 3 4.19019
CTNND1 catenin (cadherin-associated protein), delta 1 4.18694
MMP2 matrix metallopeptidase 2 4.14895
ITFG1 integrin alpha FG-GAP repeat containing 1 4.14045
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 4.11562
FAIM Fas apoptotic inhibitory molecule 4.03357
FGD1 FYVE, RhoGEF and PH domain containing 1 4.00369
BPHL biphenyl hydrolase-like (serine hydrolase) 3.98794
DPH2 DPH2 homolog (S. cerevisiae) 3.98224
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 3.97499
ISOC1 isochorismatase domain containing 1 3.93202
DGCR6L DiGeorge syndrome critical region gene 6-like 3.92784
EXD3 exonuclease 3'-5' domain containing 3 3.90754
PTK2B protein tyrosine kinase 2 beta 3.9042
WASHC5 WASH complex subunit 5 3.87479
ESRP1 epithelial splicing regulatory protein 1 3.8611
LMAN1L lectin, mannose-binding, 1 like 3.83987
ISYNA1 inositol-3-phosphate synthase 1 3.83946
MCM3 minichromosome maintenance complex component 3 3.77737
ADGRG1 adhesion G protein-coupled receptor G1 3.77602
KLF8 Kruppel-like factor 8 3.74809
EPN3 epsin 3 3.71838
CD200R1 CD200 receptor 1 3.7165
HSPB1 heat shock 27kDa protein 1 3.71432
RB1 retinoblastoma 1 3.69241
FZD1 frizzled class receptor 1 3.68734
FGF5 fibroblast growth factor 5 3.68475
GRHL2 grainyhead-like 2 (Drosophila) 3.66781
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.66608
TMEM40 transmembrane protein 40 3.65894
PRR15L proline rich 15-like 3.65708
GHRH growth hormone releasing hormone 3.65174
TEX13A testis expressed 13A 3.63993
FOXD2 forkhead box D2 3.639
DIPK1A divergent protein kinase domain 1A 3.63892
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 3.6367
SMIM40 small integral membrane protein 40 3.63638
FGFR2 fibroblast growth factor receptor 2 3.63203
RAI14 retinoic acid induced 14 3.62301
MCOLN1 mucolipin 1 3.62081
CAPN1 calpain 1, (mu/I) large subunit 3.59907
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 3.58013
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.5775
TESK1 testis-specific kinase 1 3.57572
CCL2 chemokine (C-C motif) ligand 2 3.5564
GPR45 G protein-coupled receptor 45 3.55023
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 3.54968
CALM3 calmodulin 3 (phosphorylase kinase, delta) 3.53936
ERI3 ERI1 exoribonuclease family member 3 3.52108
PPDPF pancreatic progenitor cell differentiation and proliferation factor 3.49883
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 3.48943
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 3.48594
GPR50 G protein-coupled receptor 50 3.47204
HSPB3 heat shock 27kDa protein 3 3.46289
ECH1 enoyl CoA hydratase 1, peroxisomal 3.46223
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.44369
KLHL1 kelch-like family member 1 3.43787
NVL nuclear VCP-like 3.43712
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 3.43131
IPO13 importin 13 3.41173
EGLN3 egl-9 family hypoxia-inducible factor 3 3.41002
HPSE heparanase 3.40165
STX4 syntaxin 4 3.39586
GHR growth hormone receptor 3.38127
CAMK1D calcium/calmodulin-dependent protein kinase ID 3.37775
OXCT1 3-oxoacid CoA transferase 1 3.37525
RSU1 Ras suppressor protein 1 3.36581
FBXW4 F-box and WD repeat domain containing 4 3.36221
OPRK1 opioid receptor, kappa 1 3.36046
GINS4 GINS complex subunit 4 (Sld5 homolog) 3.35783
UFD1 ubiquitin recognition factor in ER associated degradation 1 3.3516
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 3.34857
THSD4 thrombospondin, type I, domain containing 4 3.34816
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 3.34776
UNC13A unc-13 homolog A (C. elegans) 3.34426
HRK harakiri, BCL2 interacting protein 3.34192
ROGDI rogdi homolog (Drosophila) 3.33981
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 3.33698
IFT54 intraflagellar transport 54 3.33481
TEP1 telomerase-associated protein 1 3.32944
GPR32 G protein-coupled receptor 32 3.32504
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 3.31958
TOP6BL TOP6B like initiator of meiotic double strand breaks 3.31461
TMEM19 transmembrane protein 19 3.30968
ULBP1 UL16 binding protein 1 3.30908
MMP15 matrix metallopeptidase 15 (membrane-inserted) 3.29914
COPZ2 coatomer protein complex, subunit zeta 2 3.29455
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 3.29227
AP3B2 adaptor-related protein complex 3, beta 2 subunit 3.27829
LINC02854 long intergenic non-protein coding RNA 2854 3.27323
PRAMEF10 PRAME family member 10 3.26294
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 3.26164
LCN2 lipocalin 2 3.26009
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 3.25692
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 3.25214
ZNF362 zinc finger protein 362 3.23998
SH2D3A SH2 domain containing 3A 3.23934
FBXL12 F-box and leucine-rich repeat protein 12 3.23835
TSC22D3 TSC22 domain family, member 3 3.23625
SDF4 stromal cell derived factor 4 3.23187
FABP3 fatty acid binding protein 3, muscle and heart 3.22826
PRDM9 PR domain containing 9 3.226
NEU2 sialidase 2 (cytosolic sialidase) 3.2221
TBX6 T-box 6 3.22041
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 3.21949
TMEM35A transmembrane protein 35A 3.21781
JAG2 jagged 2 3.2103
ARMCX4 armadillo repeat containing, X-linked 4 3.20332
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 3.19434
USP53 ubiquitin specific peptidase 53 3.19062
PTPN14 protein tyrosine phosphatase, non-receptor type 14 3.18248
GRIK4 glutamate receptor, ionotropic, kainate 4 3.18226
POLH polymerase (DNA directed), eta 3.17429
LYN LYN proto-oncogene, Src family tyrosine kinase 3.17073
H1-5 H1.5 linker histone, cluster member 3.16582
ADGRE5 adhesion G protein-coupled receptor E5 3.16263
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 3.15752
DPYSL3 dihydropyrimidinase-like 3 3.15716
PMM2 phosphomannomutase 2 3.15357
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 3.15219
PSG2 pregnancy specific beta-1-glycoprotein 2 3.13519
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 3.13098
FMNL3 formin-like 3 3.12584
ACOT7 acyl-CoA thioesterase 7 3.11723
VEGFB vascular endothelial growth factor B 3.11319
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 3.11279
STIMATE STIM activating enhancer 3.1023
ALOXE3 arachidonate lipoxygenase 3 3.10163
GSTZ1 glutathione S-transferase zeta 1 3.09862
BIRC7 baculoviral IAP repeat containing 7 3.09785
C5AR2 complement component 5a receptor 2 3.09598
MAMLD1 mastermind-like domain containing 1 3.09452
ANO1 anoctamin 1, calcium activated chloride channel 3.09363
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 3.09176
RAD21L1 RAD21-like 1 (S. pombe) 3.08503
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 3.08252
NPDC1 neural proliferation, differentiation and control, 1 3.08109
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 3.0736
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 3.06768
TAS2R9 taste receptor, type 2, member 9 3.06524
IL3RA interleukin 3 receptor, alpha (low affinity) 3.06005
UST uronyl-2-sulfotransferase 3.05832
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 3.05617
PRMT8 protein arginine methyltransferase 8 3.05579
ZNF532 zinc finger protein 532 3.05561
STK10 serine/threonine kinase 10 3.05499
ICAM5 intercellular adhesion molecule 5, telencephalin 3.05319
AMELY amelogenin, Y-linked 3.05028
GRB7 growth factor receptor-bound protein 7 3.05006
TRHDE thyrotropin-releasing hormone degrading enzyme 3.04752
KL klotho 3.04402
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 3.03942
SPAG8 sperm associated antigen 8 3.03789
TAS2R16 taste receptor, type 2, member 16 3.03671
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 3.02569
PDE5A phosphodiesterase 5A, cGMP-specific 3.01873
ELAC1 elaC ribonuclease Z 1 3.01564
FABP6 fatty acid binding protein 6, ileal 3.01414
S100G S100 calcium binding protein G 3.00176
SORBS3 sorbin and SH3 domain containing 3 2.99726
CNOT3 CCR4-NOT transcription complex, subunit 3 2.99362
SOX2 SRY (sex determining region Y)-box 2 2.98908
GATA3 GATA binding protein 3 2.98836
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 2.98799
ZIC3 Zic family member 3 2.98045
PSG11 pregnancy specific beta-1-glycoprotein 11 2.98007
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 2.9795
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 2.9762
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 2.97551
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 2.97447
CAV1 caveolin 1, caveolae protein, 22kDa 2.97177
COQ8B coenzyme Q8B 2.96781
MMRN2 multimerin 2 2.96502
TMEM259 transmembrane protein 259 2.96435
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 2.95964
HEMK2 HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine 2.9576
PODNL1 podocan-like 1 2.9558
ARAF A-Raf proto-oncogene, serine/threonine kinase 2.94909
CYSLTR1 cysteinyl leukotriene receptor 1 2.94573
HTATSF1 HIV-1 Tat specific factor 1 2.94538
VSX1 visual system homeobox 1 2.94383
CDIP1 cell death-inducing p53 target 1 2.94166
COLEC10 collectin sub-family member 10 (C-type lectin) 2.94111
PDCL3 phosducin-like 3 2.93655
FEZF2 FEZ family zinc finger 2 2.93636
GPRC5D G protein-coupled receptor, class C, group 5, member D 2.93355
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) 2.93307
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 2.92607
IFT38 intraflagellar transport 38 2.91943
NTAN1 N-terminal asparagine amidase 2.91871
NUCB2 nucleobindin 2 2.91858
ACKR5 atypical chemokine receptor 5 2.91732
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 2.91367
PROP1 PROP paired-like homeobox 1 2.90715
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 2.90401
PALM paralemmin 2.90114
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 2.90087
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.89776
MOCS1 molybdenum cofactor synthesis 1 2.89474
PSENEN presenilin enhancer gamma secretase subunit 2.89384
SNX7 sorting nexin 7 2.89335
CAB39L calcium binding protein 39-like 2.89086
CRYZL1 crystallin, zeta (quinone reductase)-like 1 2.88983
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 2.8893
MINDY3 MINDY lysine 48 deubiquitinase 3 2.88659
CKB creatine kinase, brain 2.88527
ZFYVE21 zinc finger, FYVE domain containing 21 2.8833
KIF26B kinesin family member 26B 2.88327
MOB3B MOB kinase activator 3B 2.8813
RRH retinal pigment epithelium-derived rhodopsin homolog 2.8784
RGCC regulator of cell cycle 2.875
MMP24 matrix metallopeptidase 24 (membrane-inserted) 2.87081
SPACA1 sperm acrosome associated 1 2.86756
CHN1 chimerin 1 2.86659
BRMS1L breast cancer metastasis-suppressor 1-like 2.86536
PCDHGA11 protocadherin gamma subfamily A, 11 2.86357
EFR3B EFR3 homolog B (S. cerevisiae) 2.8615
TOMM34 translocase of outer mitochondrial membrane 34 2.86068
SUGCT succinyl-CoA:glutarate-CoA transferase 2.85838
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.85832
FAM246A family with sequence similarity 246 member A 2.8572
SIGLEC6 sialic acid binding Ig-like lectin 6 2.85521
OR2C1 olfactory receptor, family 2, subfamily C, member 1 2.8524
KLK8 kallikrein-related peptidase 8 2.85175
SARM1 sterile alpha and TIR motif containing 1 2.85059
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.84953
PFN2 profilin 2 2.84739
KERA keratocan 2.84546
SPEG SPEG complex locus 2.8443
GADD45A growth arrest and DNA-damage-inducible, alpha 2.84272
NCS1 neuronal calcium sensor 1 2.84002
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 2.83653
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.83523
CPLX3 complexin 3 2.83127
JCAD junctional cadherin 5 associated 2.82697
SART1 squamous cell carcinoma antigen recognized by T cells 2.82578
MCOLN3 mucolipin 3 2.82155
BARX1 BARX homeobox 1 2.81808
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma 2.81565
EPHA3 EPH receptor A3 2.81514
SIX3 SIX homeobox 3 2.81278
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) 2.8127
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 2.8122
TAS2R4 taste receptor, type 2, member 4 2.80347
HIKESHI heat shock protein nuclear import factor hikeshi 2.80173
PRTN3 proteinase 3 2.80103
PTPRF protein tyrosine phosphatase, receptor type, F 2.80099
RNLS renalase, FAD-dependent amine oxidase 2.80072
TRIM2 tripartite motif containing 2 2.79861
ZBTB3 zinc finger and BTB domain containing 3 2.79664
TDRD3 tudor domain containing 3 2.79662
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.79379
NPVF neuropeptide VF precursor 2.78989
BNC1 basonuclin 1 2.78982
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 2.78815
RND3 Rho family GTPase 3 2.78688
PSME3IP1 proteasome activator subunit 3 interacting protein 1 2.78213
SNX13 sorting nexin 13 2.78029
ZNF440 zinc finger protein 440 2.7768
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.77423
PCLO piccolo presynaptic cytomatrix protein 2.77384
GPER1 G protein-coupled estrogen receptor 1 2.77292
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 2.77163
IMPACT impact RWD domain protein 2.76922
ZDHHC4 zinc finger, DHHC-type containing 4 2.76916
RAB11FIP1 RAB11 family interacting protein 1 (class I) 2.76724
INA internexin neuronal intermediate filament protein, alpha 2.76289
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 2.76286
SLITRK2 SLIT and NTRK-like family, member 2 2.76121
NEUROG2 neurogenin 2 2.76073
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 2.75963
MID2 midline 2 2.75783
KIFBP kinesin family binding protein 2.75689
SSX1 synovial sarcoma, X breakpoint 1 2.75494
CPTP ceramide-1-phosphate transfer protein 2.75368
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 2.75348
STMN3 stathmin-like 3 2.75316
HSFX2 heat shock transcription factor family, X linked 2 2.75098
SCIN scinderin 2.74932
CEP131 centrosomal protein 131kDa 2.74871
CISH cytokine inducible SH2-containing protein 2.7476
ERC2 ELKS/RAB6-interacting/CAST family member 2 2.74683
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 2.74422
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) 2.74395
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 2.73897
HES2 hes family bHLH transcription factor 2 2.73808
H2BC3 H2B clustered histone 3 2.73751
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.73087
HUNK hormonally up-regulated Neu-associated kinase 2.72933
IMPG1 interphotoreceptor matrix proteoglycan 1 2.72836
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 2.72735
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 2.72696
HYI hydroxypyruvate isomerase (putative) 2.72615
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 2.72416
FLT1 fms-related tyrosine kinase 1 2.72411
TRAPPC9 trafficking protein particle complex 9 2.72297
DENND1A DENN/MADD domain containing 1A 2.72115
AMPH amphiphysin 2.72074
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 2.7202
LAMP3 lysosomal-associated membrane protein 3 2.71888
THAP7 THAP domain containing 7 2.71812
TRIM46 tripartite motif containing 46 2.71594
SEPTIN5 septin 5 2.71423
PLA2G2F phospholipase A2, group IIF 2.71402
ZNF589 zinc finger protein 589 2.71101
CALCR calcitonin receptor 2.70924
BTBD2 BTB (POZ) domain containing 2 2.70705
IMPG2 interphotoreceptor matrix proteoglycan 2 2.69967
PRKG2 protein kinase, cGMP-dependent, type II 2.69863
RNF186 ring finger protein 186 2.69284
LAGE3 L antigen family, member 3 2.69251
VGLL1 vestigial-like family member 1 2.69126
RTL8C retrotransposon Gag like 8C 2.69123
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 2.69095
CIB2 calcium and integrin binding family member 2 2.69052
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 2.68868
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 2.68737
IPP intracisternal A particle-promoted polypeptide 2.68725
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 2.68605
WDR13 WD repeat domain 13 2.68575
CLEC5A C-type lectin domain family 5, member A 2.68386
POLR1B polymerase (RNA) I polypeptide B, 128kDa 2.68341
COL4A6 collagen, type IV, alpha 6 2.68316
ANGPTL2 angiopoietin-like 2 2.67949
PTPRS protein tyrosine phosphatase, receptor type, S 2.67916
CSNK1E casein kinase 1, epsilon 2.67737
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 2.67674
TREH trehalase (brush-border membrane glycoprotein) 2.67378
TMEM212 transmembrane protein 212 2.6725
RIPPLY2-CYB5R4 RIPPLY2-CYB5R4 readthrough 2.67119
ARMCX1 armadillo repeat containing, X-linked 1 2.67082
RFX3 regulatory factor X, 3 (influences HLA class II expression) 2.66974
TEX15 testis expressed 15 2.66915
EDN2 endothelin 2 2.66739
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.6666
PDAP1 PDGFA associated protein 1 2.66595
ECHDC3 enoyl CoA hydratase domain containing 3 2.6629
OPN1MW3 opsin 1, medium wave sensitive 3 2.65998
CYB561 cytochrome b561 2.65368
ECM1 extracellular matrix protein 1 2.6527
NMBR neuromedin B receptor 2.65214
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 2.65195
PRDM14 PR domain containing 14 2.65043
PCDHGA9 protocadherin gamma subfamily A, 9 2.64898
FRMD4A FERM domain containing 4A 2.64716
DOC2A double C2-like domains, alpha 2.64714
POU6F2 POU class 6 homeobox 2 2.64663
OR2B2 olfactory receptor, family 2, subfamily B, member 2 2.64602
LOC122526780 uncharacterized LOC122526780 2.6451
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 2.64398
MEP1B meprin A, beta 2.64316
TRIM10 tripartite motif containing 10 2.64178
PLVAP plasmalemma vesicle associated protein 2.64
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 2.63747
PCDH17 protocadherin 17 2.63631
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.63601
XCL1 chemokine (C motif) ligand 1 2.63554
H2BC15 H2B clustered histone 15 2.63522
MEGF6 multiple EGF-like-domains 6 2.63433
FRAS1 Fraser extracellular matrix complex subunit 1 2.63396
FBXO40 F-box protein 40 2.63238
GPR137 G protein-coupled receptor 137 2.6313
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 2.63013
H2AJ H2A.J histone 2.62958
PDE9A phosphodiesterase 9A 2.62885
PNKP polynucleotide kinase 3'-phosphatase 2.62844
NIPAL3 NIPA-like domain containing 3 2.62716
EMX1 empty spiracles homeobox 1 2.62681
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 2.62505
AMOTL2 angiomotin like 2 2.62497
RNF103-CHMP3 RNF103-CHMP3 readthrough 2.62402
ENPEP glutamyl aminopeptidase (aminopeptidase A) 2.61898
PSG4 pregnancy specific beta-1-glycoprotein 4 2.61874
WDR62 WD repeat domain 62 2.61776
MBTD1 mbt domain containing 1 2.61632
EGF epidermal growth factor 2.61475
KITLG KIT ligand 2.61342
PTK2 protein tyrosine kinase 2 2.60976
ADGRL1 adhesion G protein-coupled receptor L1 2.60857
SDC3 syndecan 3 2.6084
TRIT1 tRNA isopentenyltransferase 1 2.60731
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 2.60443
CRX cone-rod homeobox 2.60392
POU2F3 POU class 2 homeobox 3 2.60388
RFPL3 ret finger protein-like 3 2.60356
FGF23 fibroblast growth factor 23 2.60182
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 2.60087
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 2.60055
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide 2.59934
GMPR guanosine monophosphate reductase 2.5993
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.59696
AJAP1 adherens junctions associated protein 1 2.5938
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 2.59358
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 2.59083
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 2.59017
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 2.58839
GRTP1 growth hormone regulated TBC protein 1 2.58769
DLK2 delta-like 2 homolog (Drosophila) 2.58758
METTL8 methyltransferase like 8 2.58607
TRO trophinin 2.58358
FSCN2 fascin actin-bundling protein 2, retinal 2.58332
S1PR2 sphingosine-1-phosphate receptor 2 2.58076
MAPK11 mitogen-activated protein kinase 11 2.57942
ASMT acetylserotonin O-methyltransferase 2.57629
L1TD1 LINE-1 type transposase domain containing 1 2.57627
RLN2 relaxin 2 2.5755
CDH8 cadherin 8, type 2 2.57465
ARHGAP28 Rho GTPase activating protein 28 2.57425
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 2.57405
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 2.57399
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 2.57358
ATXN10 ataxin 10 2.57352
P3H2 prolyl 3-hydroxylase 2 2.57324
RIC3 RIC3 acetylcholine receptor chaperone 2.57313
AURKB aurora kinase B 2.57222
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.5708
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.5703
ADIRF adipogenesis regulatory factor 2.56999
MTNR1A melatonin receptor 1A 2.56988
GPR85 G protein-coupled receptor 85 2.56921
PCDHA6 protocadherin alpha 6 2.56728
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.56359
STAP2 signal transducing adaptor family member 2 2.56143
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial 2.56129
OTUD7B OTU deubiquitinase 7B 2.56018
KDR kinase insert domain receptor 2.55941
GUCA2B guanylate cyclase activator 2B (uroguanylin) 2.55932
CC2D1A coiled-coil and C2 domain containing 1A 2.55579
INSRR insulin receptor-related receptor 2.55356
TBX5 T-box 5 2.55351
DBF4B DBF4 zinc finger B 2.55256
ANKH ANKH inorganic pyrophosphate transport regulator 2.55246
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 2.55223
MAGEB3 melanoma antigen family B3 2.54968
BTK Bruton agammaglobulinemia tyrosine kinase 2.54514
FKBP4 FK506 binding protein 4, 59kDa 2.54501
RTL10 retrotransposon Gag like 10 2.54313
EMC10 ER membrane protein complex subunit 10 2.54268
DCTN1 dynactin 1 2.54242
TIMCC TIM double twin CX3C motif chaperone 2.53618
FSHR follicle stimulating hormone receptor 2.53537
PDLIM1 PDZ and LIM domain 1 2.53504
MTFR1 mitochondrial fission regulator 1 2.53502
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.53457
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 2.53263
TRIM15 tripartite motif containing 15 2.53226
SSTR4 somatostatin receptor 4 2.53017
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 2.52959
SPRING1 SREBF pathway regulator in golgi 1 2.52934
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A 2.52638
COL8A2 collagen, type VIII, alpha 2 2.52634
ZNF358 zinc finger protein 358 2.5244
GAS6 growth arrest-specific 6 2.52403
UTS2 urotensin 2 2.52205
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 2.52185
KRTAP9-9 keratin associated protein 9-9 2.52112
TRHR thyrotropin-releasing hormone receptor 2.51954
MYEF2 myelin expression factor 2 2.51779
RIMS3 regulating synaptic membrane exocytosis 3 2.51665
SAMD14 sterile alpha motif domain containing 14 2.51638
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 2.51603
ZNF395 zinc finger protein 395 2.51522
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 2.51499
ANXA9 annexin A9 2.51333
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 2.51207
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 2.51117
NFU1 NFU1 iron-sulfur cluster scaffold 2.50936
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 2.50905
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 2.5073
TBXA2R thromboxane A2 receptor 2.50689
L2HGDH L-2-hydroxyglutarate dehydrogenase 2.50653
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 2.50546
ITSN1 intersectin 1 (SH3 domain protein) 2.50501
EPS8L1 EPS8-like 1 2.50328
SYNPO2 synaptopodin 2 2.50256
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 2.50202
FLT4 fms-related tyrosine kinase 4 2.50047
ATG10 autophagy related 10 2.50023
EPX eosinophil peroxidase 2.49991
TFDP3 transcription factor Dp family, member 3 2.49889
SLC17A4 solute carrier family 17, member 4 2.49692
IFT57 intraflagellar transport 57 2.4923
PLAAT2 phospholipase A and acyltransferase 2 2.49178
NPHP1 nephronophthisis 1 (juvenile) 2.49165
ZNF154 zinc finger protein 154 2.49122
VAMP7 vesicle-associated membrane protein 7 2.48872
INTS8 integrator complex subunit 8 2.48807
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 2.48795
RAB38 RAB38, member RAS oncogene family 2.48722
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.48712
OR10H1 olfactory receptor, family 10, subfamily H, member 1 2.48556
LTBP4 latent transforming growth factor beta binding protein 4 2.4842
TUBGCP2 tubulin, gamma complex associated protein 2 2.48397
CCN3 cellular communication network factor 3 2.48385
MTMR1 myotubularin related protein 1 2.48323
CLEC10A C-type lectin domain family 10, member A 2.48156
AVEN apoptosis, caspase activation inhibitor 2.48065
RNF17 ring finger protein 17 2.48034
GBX2 gastrulation brain homeobox 2 2.47657
SIM1 single-minded family bHLH transcription factor 1 2.47514
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 2.4737
PATJ PATJ crumbs cell polarity complex component 2.4711
PCDHA9 protocadherin alpha 9 2.46971
TRAP1 TNF receptor-associated protein 1 2.46807
KLK5 kallikrein-related peptidase 5 2.46794
INSL5 insulin-like 5 2.4677
TRPC7 transient receptor potential cation channel, subfamily C, member 7 2.46587
MYH1 myosin, heavy chain 1, skeletal muscle, adult 2.46513
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 2.46487
ZNF157 zinc finger protein 157 2.46318
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 2.46014
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 2.46011
DCC DCC netrin 1 receptor 2.45674
THOC6 THO complex 6 2.45446
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 2.45425
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 2.4541
FSD1 fibronectin type III and SPRY domain containing 1 2.45373
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.45207
CAV2 caveolin 2 2.45169
TP53I11 tumor protein p53 inducible protein 11 2.45152
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 2.45001
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 2.44982
ADGRB2 adhesion G protein-coupled receptor B2 2.44825
APOBR apolipoprotein B receptor 2.4461
MROH9 maestro heat-like repeat family member 9 2.44568
ANO2 anoctamin 2, calcium activated chloride channel 2.44418
LRRN2 leucine rich repeat neuronal 2 2.44386
CNKSR1 connector enhancer of kinase suppressor of Ras 1 2.44337
IQCK IQ motif containing K 2.44297
LDOC1 leucine zipper, down-regulated in cancer 1 2.44097
COL2A1 collagen, type II, alpha 1 2.44003
PTMS parathymosin 2.43934
HCAR3 hydroxycarboxylic acid receptor 3 2.43805
DNAI4 dynein axonemal intermediate chain 4 2.43787
RLN1 relaxin 1 2.43751
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2.43737
CHODL chondrolectin 2.43585
CCRL2 chemokine (C-C motif) receptor-like 2 2.43464
CCDC30 coiled-coil domain containing 30 2.43452
POU6F1 POU class 6 homeobox 1 2.43428
CTSV cathepsin V 2.43412
ACOXL acyl-CoA oxidase-like 2.43251
SIDT1 SID1 transmembrane family, member 1 2.43229
IFT140 intraflagellar transport 140 2.4318
MPC2 mitochondrial pyruvate carrier 2 2.43163
SPATA31C1 SPATA31 subfamily C, member 1 2.43062
GPALPP1 GPALPP motifs containing 1 2.43032
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 2.43027
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3 2.43003
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 2.42943
RRAGB Ras-related GTP binding B 2.42592
TBX10 T-box 10 2.42306
NOX3 NADPH oxidase 3 2.42112
H1-2 H1.2 linker histone, cluster member 2.4177
ZBED2 zinc finger, BED-type containing 2 2.41434
PXDN peroxidasin 2.41219
MTERF4 mitochondrial transcription termination factor 4 2.41112
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.40943
SPRYD7 SPRY domain containing 7 2.40901
CLIC5 chloride intracellular channel 5 2.40885
ACKR2 atypical chemokine receptor 2 2.40857
RARG retinoic acid receptor, gamma 2.40838
PGLYRP1 peptidoglycan recognition protein 1 2.40835
NUCB1 nucleobindin 1 2.40826
PDZD7 PDZ domain containing 7 2.40605
RIDA reactive intermediate imine deaminase A homolog 2.40554
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 2.40462
CCDC33 coiled-coil domain containing 33 2.40448
CD5L CD5 molecule-like 2.40439
RIMBP2 RIMS binding protein 2 2.40328
COPE coatomer protein complex, subunit epsilon 2.4024
ZIC4 Zic family member 4 2.40212
HOXA10 homeobox A10 2.40104
TLX1 T-cell leukemia homeobox 1 2.40047
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 2.39975
CALCOCO1 calcium binding and coiled-coil domain 1 2.39708
SIPA1L3 signal-induced proliferation-associated 1 like 3 2.39611
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 2.39402
SFT2D2 SFT2 domain containing 2 2.39364
SLC2A4RG SLC2A4 regulator 2.38946
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 2.38928
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 2.3878
NR5A2 nuclear receptor subfamily 5, group A, member 2 2.37934
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 2.37689
SNPH syntaphilin 2.37585
SDK2 sidekick cell adhesion molecule 2 2.37548
WFDC1 WAP four-disulfide core domain 1 2.3753
VEGFA vascular endothelial growth factor A 2.3746
KIRREL1 kirre like nephrin family adhesion molecule 1 2.37428
CNTNAP3B contactin associated protein-like 3B 2.37398
CTBP2 C-terminal binding protein 2 2.369
CBY1 chibby homolog 1 (Drosophila) 2.3686
LITAF lipopolysaccharide-induced TNF factor 2.36814
NXF3 nuclear RNA export factor 3 2.36697
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.3661
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.36548
TLR3 toll-like receptor 3 2.3627
ZNF500 zinc finger protein 500 2.36265
TMEM160 transmembrane protein 160 2.36199
HCRTR1 hypocretin (orexin) receptor 1 2.3618
ADAM18 ADAM metallopeptidase domain 18 2.361
GBA1 glucosylceramidase beta 1 2.36083
PHAF1 phagosome assembly factor 1 2.3593
PROZ protein Z, vitamin K-dependent plasma glycoprotein 2.35793
KRT12 keratin 12, type I 2.35731
LHFPL6 LHFPL tetraspan subfamily member 6 2.35569
MPDU1 mannose-P-dolichol utilization defect 1 2.35458
CCDC144A coiled-coil domain containing 144A 2.35431
SCT secretin 2.35325
NXF2B nuclear RNA export factor 2B 2.35253
TMSB4Y thymosin beta 4, Y-linked 2.35247
OR12D3 olfactory receptor, family 12, subfamily D, member 3 2.3524
CHD9NB CHD9 neighbor 2.35238
GLT8D2 glycosyltransferase 8 domain containing 2 2.35182
SYT13 synaptotagmin XIII 2.35063
NBEA neurobeachin 2.35009
SPAG7 sperm associated antigen 7 2.34965
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.34951
IFNA8 interferon, alpha 8 2.34931
CD44 CD44 molecule (Indian blood group) 2.34842
CLN3 ceroid-lipofuscinosis, neuronal 3 2.34617
EML2 echinoderm microtubule associated protein like 2 2.34522
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 2.34521
FOXM1 forkhead box M1 2.3443
PCDHA2 protocadherin alpha 2 2.34361
HOXD13 homeobox D13 2.34334
RHOD ras homolog family member D 2.34284
TBX1 T-box 1 2.34265
CCR8 chemokine (C-C motif) receptor 8 2.34205
KRT3 keratin 3, type II 2.33923
CCL1 chemokine (C-C motif) ligand 1 2.33905
THAP4 THAP domain containing 4 2.33903
CA4 carbonic anhydrase IV 2.33879
SRI sorcin 2.33876
DGKA diacylglycerol kinase, alpha 80kDa 2.33856
PROCR protein C receptor, endothelial 2.33665
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 2.33661
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 2.33623
OR51E2 olfactory receptor, family 51, subfamily E, member 2 2.33581
HSF1 heat shock transcription factor 1 2.33466
MLF2 myeloid leukemia factor 2 2.33459
IKZF2 IKAROS family zinc finger 2 (Helios) 2.3344
STEEP1 STING1 ER exit protein 1 2.33344
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 2.3325
NPTXR neuronal pentraxin receptor 2.33244
CFAP43 cilia and flagella associated protein 43 2.33216
PRDM16 PR domain containing 16 2.33033
ZNF215 zinc finger protein 215 2.32945
BMP8B bone morphogenetic protein 8b 2.3293
ADRA1A adrenoceptor alpha 1A 2.32686
OMD osteomodulin 2.32649
PSG9 pregnancy specific beta-1-glycoprotein 9 2.32628
F2RL2 coagulation factor II (thrombin) receptor-like 2 2.32605
RAB43 RAB43, member RAS oncogene family 2.3257
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 2.32512
PLPPR3 phospholipid phosphatase related 3 2.3237
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 2.32267
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 2.32257
OTULINL OTU deubiquitinase with linear linkage specificity like 2.3217
EML1 echinoderm microtubule associated protein like 1 2.32148
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.32074
CAPN9 calpain 9 2.31813
IGFBP5 insulin-like growth factor binding protein 5 2.31762
PCYT1B phosphate cytidylyltransferase 1, choline, beta 2.31699
QPCTL glutaminyl-peptide cyclotransferase-like 2.31695
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.31683
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 2.31676
PGRMC1 progesterone receptor membrane component 1 2.31672
CYB5R1 cytochrome b5 reductase 1 2.31608
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 2.31557
STEAP1B STEAP family member 1B 2.31476
VN1R1 vomeronasal 1 receptor 1 2.3135
RASL11B RAS-like, family 11, member B 2.31238
FBXW10B F-box and WD repeat domain containing 10B 2.3121
THPO thrombopoietin 2.31111
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 2.31102
HEPH hephaestin 2.31048
SCMH1 sex comb on midleg homolog 1 (Drosophila) 2.30967
ECI1 enoyl-CoA delta isomerase 1 2.30904
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 2.30866
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 2.30605
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 2.30403
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 2.30394
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 2.30373
MSMB microseminoprotein, beta- 2.30359
NHERF4 NHERF family PDZ scaffold protein 4 2.30348
CHAMP1 chromosome alignment maintaining phosphoprotein 1 2.30335
NKAIN1 Na+/K+ transporting ATPase interacting 1 2.30324
TBX4 T-box 4 2.30299
DPP4 dipeptidyl-peptidase 4 2.30285
NACAD NAC alpha domain containing 2.30265
IQSEC3 IQ motif and Sec7 domain 3 2.30124
ZNF749 zinc finger protein 749 2.3012
CNGB3 cyclic nucleotide gated channel beta 3 2.30118
TLN2 talin 2 2.29987
ABHD17A abhydrolase domain containing 17A 2.29965
RAB1B RAB1B, member RAS oncogene family 2.29947
PNPLA3 patatin-like phospholipase domain containing 3 2.29947
FETUB fetuin B 2.29917
NELL2 NEL-like 2 (chicken) 2.29775
GJA9 gap junction protein, alpha 9, 59kDa 2.29775
SORCS3 sortilin-related VPS10 domain containing receptor 3 2.2975
ARL2 ADP-ribosylation factor-like 2 2.29641
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 2.29535
PSG3 pregnancy specific beta-1-glycoprotein 3 2.29518
FYN FYN proto-oncogene, Src family tyrosine kinase 2.29494
ITM2C integral membrane protein 2C 2.29477
TAS2R7 taste receptor, type 2, member 7 2.29435
OLFM4 olfactomedin 4 2.2942
CLDN14 claudin 14 2.29383
MEF2C myocyte enhancer factor 2C 2.29381
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 2.29254
SHB Src homology 2 domain containing adaptor protein B 2.29121
IL37 interleukin 37 2.29099
CORO2A coronin, actin binding protein, 2A 2.29044
POU4F3 POU class 4 homeobox 3 2.29004
SPINT4 serine peptidase inhibitor, Kunitz type 4 2.28944
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 2.28836
APOL5 apolipoprotein L, 5 2.28783
TUBAL3 tubulin, alpha-like 3 2.28777
PSG5 pregnancy specific beta-1-glycoprotein 5 2.28556
FCRLB Fc receptor-like B 2.28449
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 2.2844
NTN3 netrin 3 2.284
ULK1 unc-51 like autophagy activating kinase 1 2.28236
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 2.28231
MBD5 methyl-CpG binding domain protein 5 2.28221
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 2.27969
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 2.27906
KLHDC3 kelch domain containing 3 2.27889
ZNF74 zinc finger protein 74 2.27889
WRNIP1 Werner helicase interacting protein 1 2.2785
CEP170B centrosomal protein 170B 2.27845
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 2.27835
PGAP6 post-GPI attachment to proteins 6 2.27695
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 2.27679
TMEM53 transmembrane protein 53 2.27617
TAS2R3 taste receptor, type 2, member 3 2.27526
CYSLTR2 cysteinyl leukotriene receptor 2 2.27455
AHCY adenosylhomocysteinase 2.27405
DOP1B DOP1 leucine zipper like protein B 2.27384
IFNA1 interferon, alpha 1 2.27233
OR2J2 olfactory receptor, family 2, subfamily J, member 2 2.27156
TTC21B tetratricopeptide repeat domain 21B 2.27084
OR7C1 olfactory receptor, family 7, subfamily C, member 1 2.26961
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 2.26849
BET1L Bet1 golgi vesicular membrane trafficking protein-like 2.26832
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 2.26812
KCNIP2 Kv channel interacting protein 2 2.26799
SULF1 sulfatase 1 2.26781
PTP4A3 protein tyrosine phosphatase type IVA, member 3 2.26772
LRRC19 leucine rich repeat containing 19 2.26728
VSIG10 V-set and immunoglobulin domain containing 10 2.26725
KLK10 kallikrein-related peptidase 10 2.26595
DNAH2 dynein, axonemal, heavy chain 2 2.26574
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.26562
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.26555
DTX3 deltex 3, E3 ubiquitin ligase 2.26506
CIRSR corepressor of RBPJ and splicing regulator 2.26443
ZFP36 ZFP36 ring finger protein 2.26377
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 2.26293
SPATA7 spermatogenesis associated 7 2.26234
HYAL4 hyaluronoglucosaminidase 4 2.26121
RHCE Rh blood group, CcEe antigens 2.26097
CNGA1 cyclic nucleotide gated channel alpha 1 2.26068
RFXANK regulatory factor X-associated ankyrin-containing protein 2.26058
TNNT3 troponin T type 3 (skeletal, fast) 2.26005
BCO1 beta-carotene oxygenase 1 2.25978
ELAVL4 ELAV like neuron-specific RNA binding protein 4 2.25911
OR10H3 olfactory receptor, family 10, subfamily H, member 3 2.25733
SPTBN2 spectrin, beta, non-erythrocytic 2 2.25689
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 2.25452
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 2.25449
TSC2 tuberous sclerosis 2 2.25443
DCAKD dephospho-CoA kinase domain containing 2.25437
TEX12 testis expressed 12 2.25417
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 2.25156
EXPH5 exophilin 5 2.25099
TMEM156 transmembrane protein 156 2.25096
IGFBP3 insulin-like growth factor binding protein 3 2.24946
RETN resistin 2.24841
PRIM1 primase, DNA, polypeptide 1 (49kDa) 2.24836
KIAA0408 KIAA0408 2.2482
SCNN1A sodium channel, non voltage gated 1 alpha subunit 2.24693
MILR1 mast cell immunoglobulin-like receptor 1 2.24665
INTS1 integrator complex subunit 1 2.24476
KIAA0930 KIAA0930 2.24422
AP1M2 adaptor-related protein complex 1, mu 2 subunit 2.24198
NHLH2 nescient helix loop helix 2 2.24152
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria 2.24134
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 2.24093
ACVRL1 activin A receptor type II-like 1 2.23841
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 2.23718
SECTM1 secreted and transmembrane 1 2.23641
IFNA6 interferon, alpha 6 2.23617
KALRN kalirin, RhoGEF kinase 2.23614
IL9 interleukin 9 2.23574
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 2.23555
GJA1 gap junction protein, alpha 1, 43kDa 2.23488
PLCH2 phospholipase C, eta 2 2.23466
BICDL1 BICD family like cargo adaptor 1 2.23453
SEC14L4 SEC14-like 4 (S. cerevisiae) 2.23195
BTC betacellulin 2.23099
EPHB1 EPH receptor B1 2.23061
GDI1 GDP dissociation inhibitor 1 2.23
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 2.22975
ANTKMT adenine nucleotide translocase lysine methyltransferase 2.22879
RFPL2 ret finger protein-like 2 2.22863
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 2.22647
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 2.22565
ZNF205 zinc finger protein 205 2.22546
IFNA2 interferon, alpha 2 2.22528
CCR9 chemokine (C-C motif) receptor 9 2.22523
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 2.22484
RBM8A RNA binding motif protein 8A 2.22452
H2BC17 H2B clustered histone 17 2.22452
PTGDR2 prostaglandin D2 receptor 2 2.22442
SDC1 syndecan 1 2.224
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 2.22373
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 2.2236
CREG1 cellular repressor of E1A-stimulated genes 1 2.22328
CASS4 Cas scaffolding protein family member 4 2.2211
MAGEA8 melanoma antigen family A8 2.22064
H2BC14 H2B clustered histone 14 2.22063
GDAP1 ganglioside induced differentiation associated protein 1 2.22061
NPY2R neuropeptide Y receptor Y2 2.21688
SHROOM2 shroom family member 2 2.2165
SLC26A4 solute carrier family 26 (anion exchanger), member 4 2.21625
PACC1 proton activated chloride channel 1 2.21606
FAM234B family with sequence similarity 234 member B 2.21574
PRKCI protein kinase C, iota 2.21458
OR52A1 olfactory receptor, family 52, subfamily A, member 1 2.21447
HOMER3 homer scaffolding protein 3 2.21336
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.21324
TRPC4 transient receptor potential cation channel, subfamily C, member 4 2.21267
PTPRU protein tyrosine phosphatase, receptor type, U 2.21252
EFNB3 ephrin-B3 2.21146
LAMB4 laminin, beta 4 2.20902
USH2A Usher syndrome 2A (autosomal recessive, mild) 2.20808
CNTNAP2 contactin associated protein-like 2 2.20807
ARID3B AT rich interactive domain 3B (BRIGHT-like) 2.20713
HSF2BP heat shock transcription factor 2 binding protein 2.20673
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 2.20346
MYH4 myosin, heavy chain 4, skeletal muscle 2.20244
VPS35L VPS35 endosomal protein sorting factor like 2.20176
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 2.20101
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 2.20093
MYOF myoferlin 2.2008
CXCR4 chemokine (C-X-C motif) receptor 4 2.20005
F8A2 coagulation factor VIII-associated 2 2.19997
BLNK B-cell linker 2.19985
PCDH11X protocadherin 11 X-linked 2.19966
ADRA2B adrenoceptor alpha 2B 2.19817
LIN28A lin-28 homolog A (C. elegans) 2.19675
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.19546
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 2.19427
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 2.19387
IRF6 interferon regulatory factor 6 2.19286
MYO1D myosin ID 2.19034
CCDC25 coiled-coil domain containing 25 2.19028
MECOM MDS1 and EVI1 complex locus 2.1895
ALOX5 arachidonate 5-lipoxygenase 2.18937
S100A14 S100 calcium binding protein A14 2.18845
CYB5R2 cytochrome b5 reductase 2 2.18771
ESRP2 epithelial splicing regulatory protein 2 2.18628
HABP2 hyaluronan binding protein 2 2.18545
COBLL1 cordon-bleu WH2 repeat protein-like 1 2.18117
EML3 echinoderm microtubule associated protein like 3 2.1808
GLRA1 glycine receptor, alpha 1 2.17935
TRIM49B tripartite motif containing 49B 2.17887
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.17834
ACOT11 acyl-CoA thioesterase 11 2.17824
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 2.17777
PAQR5 progestin and adipoQ receptor family member V 2.17765
FGF12 fibroblast growth factor 12 2.17763
ANKRD40CL ANKRD40 C-terminal like 2.17758
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 2.17757
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2.17678
GDF3 growth differentiation factor 3 2.17532
GPRASP1 G protein-coupled receptor associated sorting protein 1 2.17484
HOXB1 homeobox B1 2.1748
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 2.17449
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.1735
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 2.17202
NPY4R2 neuropeptide Y receptor Y4-2 2.17053
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 2.17018
TRPM1 transient receptor potential cation channel, subfamily M, member 1 2.16871
MOSPD1 motile sperm domain containing 1 2.168
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 2.16623
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.16609
PRSS16 protease, serine, 16 (thymus) 2.16583
SOX1 SRY (sex determining region Y)-box 1 2.16512
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 2.16462
COPS6 COP9 signalosome subunit 6 2.16356
GCM2 glial cells missing homolog 2 (Drosophila) 2.16326
IFNA7 interferon, alpha 7 2.16302
TAS2R8 taste receptor, type 2, member 8 2.16284
ACP3 acid phosphatase 3 2.1625
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 2.16162
PLS3 plastin 3 2.16079
CRIPTO3 cripto, EGF-CFC family member 3 2.15957
IFT74 intraflagellar transport 74 2.15941
LYPLA1-TCEA1 LYPLA1-TCEA1 readthrough 2.15905
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 2.15887
MED25 mediator complex subunit 25 2.15858
PAX2 paired box 2 2.15844
MAGEC1 melanoma antigen family C1 2.1581
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 2.15803
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.15793
FAM204A family with sequence similarity 204, member A 2.1579
NHLRC2 NHL repeat containing 2 2.15785
H2BC12 H2B clustered histone 12 2.15775
CDKL5 cyclin-dependent kinase-like 5 2.15767
ITFG2 integrin alpha FG-GAP repeat containing 2 2.15745
GIPC2 GIPC PDZ domain containing family, member 2 2.15731
MMP24OS MMP24 opposite strand 2.1563
PSG6 pregnancy specific beta-1-glycoprotein 6 2.15622
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 2.15513
ERMAP erythroblast membrane-associated protein (Scianna blood group) 2.15431
HOXC13 homeobox C13 2.15318
ZNF80 zinc finger protein 80 2.15307
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 2.15284
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 2.15254
SCN11A sodium channel, voltage gated, type XI alpha subunit 2.15135
FOXE3 forkhead box E3 2.15104
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 2.15054
CABP5 calcium binding protein 5 2.15013
GUCY2C guanylate cyclase 2C 2.14943
SNAP29 synaptosomal-associated protein, 29kDa 2.14846
PTCD1 pentatricopeptide repeat domain 1 2.14831
GJA4 gap junction protein, alpha 4, 37kDa 2.14752
NQO2 NAD(P)H dehydrogenase, quinone 2 2.14697
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 2.14648
VAC14 Vac14 homolog (S. cerevisiae) 2.14601
DOCK5 dedicator of cytokinesis 5 2.1457
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa 2.14564
RBM41 RNA binding motif protein 41 2.14389
OR5I1 olfactory receptor, family 5, subfamily I, member 1 2.14366

decreased expression

Symbol Name Standardized Value
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -10.0
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -10.0
CDK7 cyclin-dependent kinase 7 -10.0
MYC v-myc avian myelocytomatosis viral oncogene homolog -10.0
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -10.0
FASTKD5 FAST kinase domains 5 -10.0
IER3 immediate early response 3 -10.0
CASP3 caspase 3, apoptosis-related cysteine peptidase -9.2476
ANKRD10 ankyrin repeat domain 10 -8.74629
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -8.56073
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -8.52248
TRIB1 tribbles pseudokinase 1 -8.4804
MELK maternal embryonic leucine zipper kinase -8.33461
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -8.08013
RFC2 replication factor C (activator 1) 2, 40kDa -7.99236
C2CD5 C2 calcium-dependent domain containing 5 -7.78304
NCK1 NCK adaptor protein 1 -7.52849
NUP85 nucleoporin 85kDa -7.50675
DUSP6 dual specificity phosphatase 6 -7.28558
TWF2 twinfilin actin binding protein 2 -7.2059
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -7.16047
KHDC4 KH domain containing 4, pre-mRNA splicing factor -7.1282
DDIT4 DNA-damage-inducible transcript 4 -7.10713
KEAP1 kelch-like ECH-associated protein 1 -7.06904
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -6.94928
TXLNA taxilin alpha -6.67892
ZW10 zw10 kinetochore protein -6.61015
GOLT1B golgi transport 1B -6.50324
THAP11 THAP domain containing 11 -6.4057
TOP2A topoisomerase (DNA) II alpha 170kDa -6.37482
LBR lamin B receptor -6.3148
PCNA proliferating cell nuclear antigen -6.29813
ZMIZ1 zinc finger, MIZ-type containing 1 -6.15901
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -6.0279
TXNRD1 thioredoxin reductase 1 -5.99495
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -5.72151
NUP62 nucleoporin 62kDa -5.70602
CGRRF1 cell growth regulator with ring finger domain 1 -5.65614
RNMT RNA (guanine-7-) methyltransferase -5.49142
CCNB2 cyclin B2 -5.44725
TCERG1 transcription elongation regulator 1 -5.38161
TCTN1 tectonic family member 1 -5.3712
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -5.35364
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -5.31839
TATDN2 TatD DNase domain containing 2 -5.13061
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -5.11472
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -5.06577
JMJD6 jumonji domain containing 6 -4.99832
EAPP E2F-associated phosphoprotein -4.96692
ADO 2-aminoethanethiol (cysteamine) dioxygenase -4.8528
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.80838
ZNF586 zinc finger protein 586 -4.76917
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -4.74247
GLOD4 glyoxalase domain containing 4 -4.71009
CASC3 cancer susceptibility candidate 3 -4.60792
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -4.58403
EGR1 early growth response 1 -4.53413
FAT1 FAT atypical cadherin 1 -4.51012
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -4.42062
GNAS GNAS complex locus -4.3518
ATMIN ATM interactor -4.29736
CD58 CD58 molecule -4.26486
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.22489
CDK1 cyclin-dependent kinase 1 -4.21685
MACF1 microtubule-actin crosslinking factor 1 -4.21614
CYTH1 cytohesin 1 -4.20417
INTS3 integrator complex subunit 3 -4.20156
CEP76 centrosomal protein 76kDa -4.17081
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -4.15269
CDC25B cell division cycle 25B -4.1454
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.10765
CCNA2 cyclin A2 -4.0489
MAT2A methionine adenosyltransferase II, alpha -4.04128
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -4.04037
UGDH UDP-glucose 6-dehydrogenase -4.01278
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -3.98565
FOSL1 FOS-like antigen 1 -3.97607
KIF14 kinesin family member 14 -3.9586
VGLL4 vestigial-like family member 4 -3.94377
PRPF38B pre-mRNA processing factor 38B -3.93438
HOXA5 homeobox A5 -3.91948
UBE3C ubiquitin protein ligase E3C -3.90439
KDM3A lysine (K)-specific demethylase 3A -3.89988
UFM1 ubiquitin-fold modifier 1 -3.87849
INPP1 inositol polyphosphate-1-phosphatase -3.81963
AKAP8 A kinase (PRKA) anchor protein 8 -3.80489
TM9SF3 transmembrane 9 superfamily member 3 -3.80166
CAPN7 calpain 7 -3.78756
TLR4 toll-like receptor 4 -3.72748
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.67344
SRP54 signal recognition particle 54kDa -3.65292
TLCD3A TLC domain containing 3A -3.64157
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 -3.61337
NOP56 NOP56 ribonucleoprotein -3.57957
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -3.55854
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -3.55814
SPAG4 sperm associated antigen 4 -3.54305
ZNF443 zinc finger protein 443 -3.53865
LOC124907782 dual specificity protein phosphatase 22 -3.52801
NRIP1 nuclear receptor interacting protein 1 -3.52045
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.50068
C5 complement component 5 -3.46848
BLCAP bladder cancer associated protein -3.43857
ZCCHC8 zinc finger, CCHC domain containing 8 -3.43834
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) -3.41928
ZDHHC6 zinc finger, DHHC-type containing 6 -3.41762
MSH6 mutS homolog 6 -3.41664
AKAP10 A kinase (PRKA) anchor protein 10 -3.3955
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.3876
SPRY2 sprouty homolog 2 (Drosophila) -3.36943
CHSY1 chondroitin sulfate synthase 1 -3.36756
WDR82 WD repeat domain 82 -3.36752
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing -3.3673
MLEC malectin -3.30996
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -3.30798
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -3.29423
SESN1 sestrin 1 -3.25617
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -3.25493
SCAF8 SR-related CTD-associated factor 8 -3.24612
GRWD1 glutamate-rich WD repeat containing 1 -3.24508
ZBTB11 zinc finger and BTB domain containing 11 -3.24315
COPB1 coatomer protein complex, subunit beta 1 -3.22234
IST1 increased sodium tolerance 1 homolog (yeast) -3.21531
GTPBP8 GTP-binding protein 8 (putative) -3.19252
SNUPN snurportin 1 -3.18988
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 -3.17934
RNASE7 ribonuclease, RNase A family, 7 -3.1778
CAB39 calcium binding protein 39 -3.16714
BCL10 B-cell CLL/lymphoma 10 -3.14568
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.1409
AURKA aurora kinase A -3.12685
RBM14-RBM4 RBM14-RBM4 readthrough -3.12583
CLTC clathrin, heavy chain (Hc) -3.11646
ZNHIT3 zinc finger, HIT-type containing 3 -3.11001
DCK deoxycytidine kinase -3.10544
GGNBP2 gametogenetin binding protein 2 -3.10392
TFB2M transcription factor B2, mitochondrial -3.08047
AARS1 alanyl-tRNA synthetase 1 -3.07004
PUM2 pumilio RNA-binding family member 2 -3.06757
ZNF184 zinc finger protein 184 -3.04712
WEE1 WEE1 G2 checkpoint kinase -3.04117
ADAM10 ADAM metallopeptidase domain 10 -3.02966
ARID4A AT rich interactive domain 4A (RBP1-like) -3.02193
RPL36AL ribosomal protein L36a-like -3.0163
PRDX1 peroxiredoxin 1 -3.0071
GOLGA3 golgin A3 -3.0009
MKRN2 makorin ring finger protein 2 -2.99939
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.99874
ZNF207 zinc finger protein 207 -2.99472
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -2.98363
PCF11 PCF11 cleavage and polyadenylation factor subunit -2.96961
GOLPH3L golgi phosphoprotein 3-like -2.96742
MRPL46 mitochondrial ribosomal protein L46 -2.96671
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -2.93244
SPTAN1 spectrin, alpha, non-erythrocytic 1 -2.9297
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.92599
MGA MGA, MAX dimerization protein -2.91026
TEFM transcription elongation factor, mitochondrial -2.87289
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) -2.87246
GRPEL1 GrpE-like 1, mitochondrial (E. coli) -2.86657
ZFYVE16 zinc finger, FYVE domain containing 16 -2.8616
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.85999
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -2.85167
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.84519
DHRS2 dehydrogenase/reductase (SDR family) member 2 -2.84453
SRPRB signal recognition particle receptor, B subunit -2.84339
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa -2.84236
MAPK6 mitogen-activated protein kinase 6 -2.83797
RPS4Y1 ribosomal protein S4, Y-linked 1 -2.82501
DUSP14 dual specificity phosphatase 14 -2.82434
MARCKSL1 MARCKS-like 1 -2.82247
NINJ2 ninjurin 2 -2.81822
ETNK1 ethanolamine kinase 1 -2.81173
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -2.79247
TFAM transcription factor A, mitochondrial -2.78636
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.77878
IPO7 importin 7 -2.77174
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -2.76649
SKIC2 SKI2 subunit of superkiller complex -2.75886
RALGDS ral guanine nucleotide dissociation stimulator -2.75506
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -2.75254
SRC SRC proto-oncogene, non-receptor tyrosine kinase -2.74187
NISCH nischarin -2.73949
RBM7 RNA binding motif protein 7 -2.73819
SUCO SUN domain containing ossification factor -2.73603
PUF60 poly-U binding splicing factor 60KDa -2.72348
MGST2 microsomal glutathione S-transferase 2 -2.71968
AFG3L2 AFG3-like AAA ATPase 2 -2.71351
LMO2 LIM domain only 2 (rhombotin-like 1) -2.70774
RRAGA Ras-related GTP binding A -2.70727
PLAT plasminogen activator, tissue -2.70604
MVP major vault protein -2.70332
EIF5 eukaryotic translation initiation factor 5 -2.70161
CRYZ crystallin, zeta (quinone reductase) -2.69666
TRAF1 TNF receptor-associated factor 1 -2.69488
NUP153 nucleoporin 153kDa -2.6905
LARP4 La ribonucleoprotein domain family, member 4 -2.68864
NPTN neuroplastin -2.68718
TUBB6 tubulin, beta 6 class V -2.68498
GABPB1 GA binding protein transcription factor, beta subunit 1 -2.68104
SASH3 SAM and SH3 domain containing 3 -2.67517
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.67486
CMC2 C-x(9)-C motif containing 2 -2.67481
MED21 mediator complex subunit 21 -2.67065
CST4 cystatin S -2.66566
IQGAP2 IQ motif containing GTPase activating protein 2 -2.65907
CDPF1 cysteine-rich, DPF motif domain containing 1 -2.65838
TASOR transcription activation suppressor -2.65775
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.65671
FAM216A family with sequence similarity 216, member A -2.65588
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -2.6381
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) -2.62941
TBP TATA box binding protein -2.62426
SSUH2 ssu-2 homolog (C. elegans) -2.61891
SMC4 structural maintenance of chromosomes 4 -2.61537
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.60919
ARGLU1 arginine and glutamate rich 1 -2.60739
CHERP calcium homeostasis endoplasmic reticulum protein -2.60221
IP6K2 inositol hexakisphosphate kinase 2 -2.59333
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -2.59156
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.58147
RECQL RecQ helicase-like -2.58102
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -2.57786
ZC3H11B zinc finger CCCH-type containing 11B pseudogene -2.57648
ZBTB35 zinc finger and BTB domain containing 35 -2.56834
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -2.56708
INTS13 integrator complex subunit 13 -2.5668
RTRAF RNA transcription, translation and transport factor -2.55694
NUP98 nucleoporin 98kDa -2.55584
ZNF143 zinc finger protein 143 -2.54045
ANKRD17 ankyrin repeat domain 17 -2.54026
CTR9 CTR9, Paf1/RNA polymerase II complex component -2.53332
VMP1 vacuole membrane protein 1 -2.53043
RBM6 RNA binding motif protein 6 -2.52717
TRAPPC4 trafficking protein particle complex 4 -2.52372
USP1 ubiquitin specific peptidase 1 -2.51856
IGFBP1 insulin-like growth factor binding protein 1 -2.51511
ZNF107 zinc finger protein 107 -2.51169
RNF4 ring finger protein 4 -2.51081
RBM15 RNA binding motif protein 15 -2.50826
GMFB glia maturation factor, beta -2.49819
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -2.49054
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -2.48888
CST2 cystatin SA -2.48578
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.48069
CRLF3 cytokine receptor-like factor 3 -2.48051
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -2.47753
ELF2 E74-like factor 2 (ets domain transcription factor) -2.46965
TRIM27 tripartite motif containing 27 -2.46419
USO1 USO1 vesicle transport factor -2.45648
MANF mesencephalic astrocyte-derived neurotrophic factor -2.4555
RELN reelin -2.45534
HEATR1 HEAT repeat containing 1 -2.44793
ODAM odontogenic, ameloblast asssociated -2.44573
RHOF ras homolog family member F (in filopodia) -2.44374
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.44309
USPL1 ubiquitin specific peptidase like 1 -2.44131
FNBP4 formin binding protein 4 -2.43711
CKAP5 cytoskeleton associated protein 5 -2.437
SOX4 SRY (sex determining region Y)-box 4 -2.43554
KRT7 keratin 7, type II -2.43481
IL6ST interleukin 6 signal transducer -2.4346
EIF4H eukaryotic translation initiation factor 4H -2.42901
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 -2.42751
TOMM70 translocase of outer mitochondrial membrane 70 -2.42748
CHL1 cell adhesion molecule L1-like -2.42472
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -2.41834
LASP1 LIM and SH3 protein 1 -2.41767
HDAC2 histone deacetylase 2 -2.41252
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.40712
TMEM185B transmembrane protein 185B -2.40407
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.39797
TFB1M transcription factor B1, mitochondrial -2.38631
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -2.38369
CEP192 centrosomal protein 192kDa -2.3833
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -2.38169
NOL11 nucleolar protein 11 -2.38037
HHEX hematopoietically expressed homeobox -2.38006
FRYL FRY-like -2.37964
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -2.36435
SDF2 stromal cell-derived factor 2 -2.36131
TMEM11 transmembrane protein 11 -2.35904
OXA1L oxidase (cytochrome c) assembly 1-like -2.35546
ZNF266 zinc finger protein 266 -2.35545
RHOT1 ras homolog family member T1 -2.34527
DCPH1 damage control phosphatase 1 -2.34494
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 -2.34202
S100PBP S100P binding protein -2.34168
DPY19L1 dpy-19-like 1 (C. elegans) -2.34002
CDK6 cyclin-dependent kinase 6 -2.33817
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.33709
RFX7 regulatory factor X, 7 -2.33212
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 -2.33061
NPC1 Niemann-Pick disease, type C1 -2.32438
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -2.31682
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -2.30834
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -2.30813
ZNF106 zinc finger protein 106 -2.3058
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 -2.3025
DNM1L dynamin 1-like -2.30143
CRBN cereblon -2.29972
KIF2C kinesin family member 2C -2.29921
FOXO4 forkhead box O4 -2.29824
UBE4A ubiquitination factor E4A -2.29434
CHMP1B charged multivesicular body protein 1B -2.28941
SPDL1 spindle apparatus coiled-coil protein 1 -2.28664
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 -2.28162
DEK DEK proto-oncogene -2.28141
SMG8 SMG8 nonsense mediated mRNA decay factor -2.27446
CST1 cystatin SN -2.26933
ZZZ3 zinc finger, ZZ-type containing 3 -2.26727
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -2.26183
MYLK myosin light chain kinase -2.25993
RNF111 ring finger protein 111 -2.25821
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 -2.25771
SUZ12 SUZ12 polycomb repressive complex 2 subunit -2.25519
ZNF189 zinc finger protein 189 -2.25347
WASHC4 WASH complex subunit 4 -2.25346
TBC1D3G TBC1 domain family member 3G -2.25336
SCML2 sex comb on midleg-like 2 (Drosophila) -2.24841
MOGAT2 monoacylglycerol O-acyltransferase 2 -2.24657
NRBF2 nuclear receptor binding factor 2 -2.24204
MIS12 MIS12 kinetochore complex component -2.23295
TM2D3 TM2 domain containing 3 -2.2322
EMID1 EMI domain containing 1 -2.2309
BLM Bloom syndrome, RecQ helicase-like -2.23045
CEP170 centrosomal protein 170kDa -2.23035
GCA grancalcin, EF-hand calcium binding protein -2.22986
TMEM115 transmembrane protein 115 -2.22712
SYNGR3 synaptogyrin 3 -2.22644
CENPN centromere protein N -2.22195
ZBTB25 zinc finger and BTB domain containing 25 -2.2213
SETX senataxin -2.21773
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 -2.21654
PLS1 plastin 1 -2.21269
EFHD2 EF-hand domain family, member D2 -2.21232
SKAP2 src kinase associated phosphoprotein 2 -2.21022
CST3 cystatin C -2.20996
TM4SF1 transmembrane 4 L six family member 1 -2.20938
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.20134
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -2.19842
GLB1 galactosidase, beta 1 -2.19777
AHSG alpha-2-HS-glycoprotein -2.19707
SACS sacsin molecular chaperone -2.19205
WDR6 WD repeat domain 6 -2.18732
CLCN6 chloride channel, voltage-sensitive 6 -2.18544
PDCD6IP programmed cell death 6 interacting protein -2.18391
CKLF-CMTM1 CKLF-CMTM1 readthrough -2.17959
TRAPPC3 trafficking protein particle complex 3 -2.17731
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -2.17687
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma -2.17229
ATAD2 ATPase family, AAA domain containing 2 -2.17199
MAK16 MAK16 homolog (S. cerevisiae) -2.16656
KDM5A lysine (K)-specific demethylase 5A -2.16497
PTS 6-pyruvoyltetrahydropterin synthase -2.16475
WDR37 WD repeat domain 37 -2.16388
TBC1D4 TBC1 domain family, member 4 -2.1625
UBA3 ubiquitin-like modifier activating enzyme 3 -2.16058
TM9SF2 transmembrane 9 superfamily member 2 -2.16007
GALK1 galactokinase 1 -2.1538
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 -2.15176
ZFC3H1 zinc finger, C3H1-type containing -2.15078
PPID peptidylprolyl isomerase D -2.1474
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.1449
KIAA0586 KIAA0586 -2.13805
MED28 mediator complex subunit 28 -2.13776
RBM25 RNA binding motif protein 25 -2.13153
TACC3 transforming, acidic coiled-coil containing protein 3 -2.13072
TMX1 thioredoxin-related transmembrane protein 1 -2.12959
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.12678
RAB11A RAB11A, member RAS oncogene family -2.12673
PLIN3 perilipin 3 -2.1256
U2SURP U2 snRNP-associated SURP domain containing -2.12298
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.11798
CDKN2A cyclin-dependent kinase inhibitor 2A -2.11685
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -2.11678
LIF leukemia inhibitory factor -2.11674
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -2.11461
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.11321
INSIG2 insulin induced gene 2 -2.11134
TUBD1 tubulin, delta 1 -2.11113
CPAP centrosome assembly and centriole elongation protein -2.11039
PEG3 paternally expressed 3 -2.10957
IGHMBP2 immunoglobulin mu binding protein 2 -2.10739
TUSC2 tumor suppressor candidate 2 -2.1051
CCNL1 cyclin L1 -2.10458
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 -2.10349
DET1 de-etiolated homolog 1 (Arabidopsis) -2.09348
COASY CoA synthase -2.09307
SLF2 SMC5-SMC6 complex localization factor 2 -2.08928
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -2.08761
BCL6 B-cell CLL/lymphoma 6 -2.08644
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -2.08593
NKAPD1 NKAP domain containing 1 -2.08561
CBFB core-binding factor, beta subunit -2.08405
SMC1A structural maintenance of chromosomes 1A -2.08207
ARID5B AT rich interactive domain 5B (MRF1-like) -2.07959
PNRC2 proline-rich nuclear receptor coactivator 2 -2.07599
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -2.07502
RAB22A RAB22A, member RAS oncogene family -2.07472
CCDC93 coiled-coil domain containing 93 -2.07174
FRG1 FSHD region gene 1 -2.06923
ASTE1 asteroid homolog 1 (Drosophila) -2.06904
EML4 echinoderm microtubule associated protein like 4 -2.06626
NOAZFP nucleolar atypical zinc finger -2.06557
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -2.06456
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -2.06149
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -2.06112
RANBP2 RAN binding protein 2 -2.06091
SLC25A46 solute carrier family 25, member 46 -2.05986
CDKN2AIP CDKN2A interacting protein -2.05842
TERF2IP telomeric repeat binding factor 2, interacting protein -2.05666
TOP2B topoisomerase (DNA) II beta 180kDa -2.05495
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -2.05472
TMED1 transmembrane emp24 protein transport domain containing 1 -2.05449
PITX1 paired-like homeodomain 1 -2.05004
SLC25A44 solute carrier family 25, member 44 -2.04781
BCOR BCL6 corepressor -2.04139
THOC1 THO complex 1 -2.03904
SNX5 sorting nexin 5 -2.03726
ASXL1 additional sex combs like transcriptional regulator 1 -2.03501
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -2.03362
MRPS7 mitochondrial ribosomal protein S7 -2.0323
CENPE centromere protein E, 312kDa -2.03159
MFAP1 microfibrillar-associated protein 1 -2.03131
GTF2B general transcription factor IIB -2.03117
PMPCA peptidase (mitochondrial processing) alpha -2.02521
CNPY3 canopy FGF signaling regulator 3 -2.02065
UBP1 upstream binding protein 1 (LBP-1a) -2.01955
BZW1 basic leucine zipper and W2 domains 1 -2.01823
WDR43 WD repeat domain 43 -2.01789
BCLAF1 BCL2-associated transcription factor 1 -2.01487
LAP3 leucine aminopeptidase 3 -2.01485
SNIP1 Smad nuclear interacting protein 1 -2.01176
AHCTF1 AT hook containing transcription factor 1 -2.01068
DSG2 desmoglein 2 -2.01061
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.00563
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -2.00537
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -2.0041
STAT5A signal transducer and activator of transcription 5A -2.00165
GCH1 GTP cyclohydrolase 1 -2.00132
SIX1 SIX homeobox 1 -2.00057
GPC3 glypican 3 -2.00025