CRCGN010_HEPG2_24H:C22 Gene Set

Dataset	Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category	transcriptomics
Type	small molecule perturbation
Description	mitoxantrone 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1774 genes differentially expressed following the CRCGN010_HEPG2_24H:C22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol	Name	Standardized Value
INPP1	inositol polyphosphate-1-phosphatase	10.0
ABHD4	abhydrolase domain containing 4	10.0
BLCAP	bladder cancer associated protein	10.0
P4HA2	prolyl 4-hydroxylase, alpha polypeptide II	9.06747
H2BC21	H2B clustered histone 21	8.6864
CCDC92	coiled-coil domain containing 92	8.4087
POLD4	polymerase (DNA-directed), delta 4, accessory subunit	8.27272
DDB2	damage-specific DNA binding protein 2, 48kDa	8.07264
NOTCH1	notch 1	8.02501
MCOLN1	mucolipin 1	7.91151
H2BC12	H2B clustered histone 12	7.85765
FOSL1	FOS-like antigen 1	7.84159
CPSF4	cleavage and polyadenylation specific factor 4, 30kDa	7.60646
NR1H2	nuclear receptor subfamily 1, group H, member 2	7.50898
GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	7.44325
IGFBP3	insulin-like growth factor binding protein 3	7.27517
LRP10	low density lipoprotein receptor-related protein 10	7.25744
TIMP2	TIMP metallopeptidase inhibitor 2	7.16576
CTSD	cathepsin D	6.94771
TRAPPC6A	trafficking protein particle complex 6A	6.91025
CXCR4	chemokine (C-X-C motif) receptor 4	6.87176
DFFA	DNA fragmentation factor, 45kDa, alpha polypeptide	6.80486
EGR1	early growth response 1	6.66423
GPC1	glypican 1	6.65624
GADD45A	growth arrest and DNA-damage-inducible, alpha	6.64928
EDN1	endothelin 1	6.61255
MVP	major vault protein	6.59811
RFNG	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	6.52676
DUSP14	dual specificity phosphatase 14	6.4973
PPP1R13B	protein phosphatase 1, regulatory subunit 13B	6.47354
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	6.4316
ZFP36	ZFP36 ring finger protein	6.23152
SOX2	SRY (sex determining region Y)-box 2	6.15959
TUBB6	tubulin, beta 6 class V	6.01954
ROBO3	roundabout, axon guidance receptor, homolog 3 (Drosophila)	6.01421
UBE2L6	ubiquitin-conjugating enzyme E2L 6	5.97487
PRKCQ	protein kinase C, theta	5.86616
IFNAR1	interferon (alpha, beta and omega) receptor 1	5.85084
TNIP1	TNFAIP3 interacting protein 1	5.79788
ADGRG1	adhesion G protein-coupled receptor G1	5.76416
TERF2IP	telomeric repeat binding factor 2, interacting protein	5.73528
DNAJB2	DnaJ (Hsp40) homolog, subfamily B, member 2	5.55276
CHAC1	ChaC glutathione-specific gamma-glutamylcyclotransferase 1	5.50222
LSR	lipolysis stimulated lipoprotein receptor	5.50049
P4HTM	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	5.43895
C2CD2L	C2CD2-like	5.42498
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	5.41205
TERT	telomerase reverse transcriptase	5.39163
STX4	syntaxin 4	5.36005
MAD2L1BP	MAD2L1 binding protein	5.31999
PLA2G15	phospholipase A2, group XV	5.29608
PRKCD	protein kinase C, delta	5.24857
GHR	growth hormone receptor	5.23313
CIAO3	cytosolic iron-sulfur assembly component 3	5.20614
HSPA1A	heat shock 70kDa protein 1A	5.19518
SOCS2	suppressor of cytokine signaling 2	5.18149
PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	5.16795
MICALL1	MICAL-like 1	5.16703
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	5.1571
ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	5.13222
TESK1	testis-specific kinase 1	5.12767
FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)	5.10667
SMIM40	small integral membrane protein 40	5.08656
TENT4A	terminal nucleotidyltransferase 4A	5.04481
NPDC1	neural proliferation, differentiation and control, 1	5.02876
CGRRF1	cell growth regulator with ring finger domain 1	4.99827
TBPL1	TBP-like 1	4.98046
ARL4C	ADP-ribosylation factor-like 4C	4.96384
PTK2B	protein tyrosine kinase 2 beta	4.96056
SGCB	sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)	4.95789
MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	4.94011
ZNF79	zinc finger protein 79	4.87448
HSPB1	heat shock 27kDa protein 1	4.84673
MMP2	matrix metallopeptidase 2	4.80542
UFM1	ubiquitin-fold modifier 1	4.78988
CCNA1	cyclin A1	4.7542
TOR1A	torsin family 1, member A (torsin A)	4.69226
CEBPZ	CCAAT/enhancer binding protein (C/EBP), zeta	4.68509
ITFG1	integrin alpha FG-GAP repeat containing 1	4.67008
S100A13	S100 calcium binding protein A13	4.63985
H1-2	H1.2 linker histone, cluster member	4.6361
TRIM8	tripartite motif containing 8	4.61373
PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)	4.61336
GFOD1	glucose-fructose oxidoreductase domain containing 1	4.60495
TIGAR	TP53 induced glycolysis regulatory phosphatase	4.53011
PIGT	phosphatidylinositol glycan anchor biosynthesis, class T	4.51359
CTSL	cathepsin L	4.48481
PTK2	protein tyrosine kinase 2	4.47756
TRIM13	tripartite motif containing 13	4.46281
RBM15B	RNA binding motif protein 15B	4.45569
UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1	4.45365
TCEA2	transcription elongation factor A (SII), 2	4.40672
NIT1	nitrilase 1	4.36462
FPGS	folylpolyglutamate synthase	4.36019
ZW10	zw10 kinetochore protein	4.35369
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	4.33777
ZKSCAN4	zinc finger with KRAB and SCAN domains 4	4.31387
MOK	MOK protein kinase	4.27627
LCN2	lipocalin 2	4.27415
SLC27A3	solute carrier family 27 (fatty acid transporter), member 3	4.26982
IL4R	interleukin 4 receptor	4.25824
TGFB1I1	transforming growth factor beta 1 induced transcript 1	4.25537
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	4.24777
BECN1	beclin 1, autophagy related	4.23663
H2AC25	H2A clustered histone 25	4.22438
TREM1	triggering receptor expressed on myeloid cells 1	4.18696
RALGDS	ral guanine nucleotide dissociation stimulator	4.17099
JUN	jun proto-oncogene	4.14612
ANKRA2	ankyrin repeat, family A (RFXANK-like), 2	4.14301
KDM5A	lysine (K)-specific demethylase 5A	4.12478
EED	embryonic ectoderm development	4.10555
DGKA	diacylglycerol kinase, alpha 80kDa	4.06632
H2AC7	H2A clustered histone 7	4.05706
PLK3	polo-like kinase 3	4.0456
MEST	mesoderm specific transcript	4.04411
PPIE	peptidylprolyl isomerase E (cyclophilin E)	4.01717
SCPEP1	serine carboxypeptidase 1	4.01192
PHLDA3	pleckstrin homology-like domain, family A, member 3	3.97773
PTPRF	protein tyrosine phosphatase, receptor type, F	3.96962
MTCH1	mitochondrial carrier 1	3.96835
GRN	granulin	3.96104
IER3	immediate early response 3	3.95968
CSNK1G1	casein kinase 1, gamma 1	3.95651
DPH2	DPH2 homolog (S. cerevisiae)	3.95246
PHF1	PHD finger protein 1	3.95238
LRPAP1	low density lipoprotein receptor-related protein associated protein 1	3.94752
DYRK3	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3	3.94648
FOXO4	forkhead box O4	3.9345
H2AC6	H2A clustered histone 6	3.93008
SESN1	sestrin 1	3.92353
ARMCX4	armadillo repeat containing, X-linked 4	3.91426
MYLIP	myosin regulatory light chain interacting protein	3.90988
SH3BP5	SH3-domain binding protein 5 (BTK-associated)	3.90575
HLX	H2.0-like homeobox	3.89417
ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	3.89149
TPBG	trophoblast glycoprotein	3.88751
THSD1	thrombospondin, type I, domain containing 1	3.88339
H2AC19	H2A clustered histone 19	3.87245
IL1B	interleukin 1, beta	3.86959
ALAS1	5'-aminolevulinate synthase 1	3.85699
NOL3	nucleolar protein 3 (apoptosis repressor with CARD domain)	3.85419
HPSE	heparanase	3.81331
TREM2	triggering receptor expressed on myeloid cells 2	3.79124
CYB561	cytochrome b561	3.78446
IPO13	importin 13	3.78436
SLFN12	schlafen family member 12	3.78346
PI4K2A	phosphatidylinositol 4-kinase type 2 alpha	3.76555
CALHM2	calcium homeostasis modulator 2	3.76153
MMRN2	multimerin 2	3.75979
RNF25	ring finger protein 25	3.75941
VPS28	vacuolar protein sorting 28 homolog (S. cerevisiae)	3.75666
CNPY4	canopy FGF signaling regulator 4	3.74813
GABARAPL1	GABA(A) receptor-associated protein like 1	3.7378
SCAND1	SCAN domain containing 1	3.72802
PARP6	poly (ADP-ribose) polymerase family, member 6	3.72705
FRS2	fibroblast growth factor receptor substrate 2	3.71861
PTPRE	protein tyrosine phosphatase, receptor type, E	3.71217
FLT1	fms-related tyrosine kinase 1	3.71142
BCAS2	breast carcinoma amplified sequence 2	3.71081
SLCO3A1	solute carrier organic anion transporter family, member 3A1	3.7039
KCNJ2	potassium channel, inwardly rectifying subfamily J, member 2	3.6921
MOCS1	molybdenum cofactor synthesis 1	3.68392
RNF139	ring finger protein 139	3.68052
NUDT9	nudix (nucleoside diphosphate linked moiety X)-type motif 9	3.66849
SNX7	sorting nexin 7	3.66285
PNRC1	proline-rich nuclear receptor coactivator 1	3.6625
PRKX	protein kinase, X-linked	3.66215
NT5E	5'-nucleotidase, ecto (CD73)	3.65184
FASTKD5	FAST kinase domains 5	3.64647
GAS6	growth arrest-specific 6	3.64108
MRPL33	mitochondrial ribosomal protein L33	3.60705
JAG2	jagged 2	3.60611
RBM41	RNA binding motif protein 41	3.59996
SETD1A	SET domain containing 1A	3.59694
ZBTB43	zinc finger and BTB domain containing 43	3.5954
CPM	carboxypeptidase M	3.58969
TSC22D3	TSC22 domain family, member 3	3.57651
YIPF3	Yip1 domain family, member 3	3.57565
TRIM11	tripartite motif containing 11	3.56217
CSNK1E	casein kinase 1, epsilon	3.56015
PRAF2	PRA1 domain family, member 2	3.55388
ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1	3.54924
ANO10	anoctamin 10	3.54911
TBXA2R	thromboxane A2 receptor	3.5446
CIC	capicua transcriptional repressor	3.54424
PTMS	parathymosin	3.54423
TCF15	transcription factor 15 (basic helix-loop-helix)	3.53445
SMAD3	SMAD family member 3	3.53424
ZNF34	zinc finger protein 34	3.52965
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	3.52207
CNIH4	cornichon family AMPA receptor auxiliary protein 4	3.52169
DUSP6	dual specificity phosphatase 6	3.519
YPEL5	yippee-like 5 (Drosophila)	3.51648
DNM1	dynamin 1	3.51476
ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)	3.51154
ATP6V1B1	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1	3.50402
BACE2	beta-site APP-cleaving enzyme 2	3.5024
MAP7D1	MAP7 domain containing 1	3.48939
RNF122	ring finger protein 122	3.48707
ATG12	autophagy related 12	3.48608
EHD2	EH-domain containing 2	3.47919
RGL2	ral guanine nucleotide dissociation stimulator-like 2	3.47026
ELF4	E74-like factor 4 (ets domain transcription factor)	3.46886
TSPYL2	TSPY-like 2	3.45786
DOK7	docking protein 7	3.45392
RALA	v-ral simian leukemia viral oncogene homolog A (ras related)	3.45212
JCAD	junctional cadherin 5 associated	3.45053
SPI1	Spi-1 proto-oncogene	3.44375
UBE2A	ubiquitin-conjugating enzyme E2A	3.43921
FAM246A	family with sequence similarity 246 member A	3.42511
MRC1	mannose receptor, C type 1	3.42483
MNT	MAX network transcriptional repressor	3.42395
EDN2	endothelin 2	3.42112
TAF1C	TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa	3.41968
CSRNP2	cysteine-serine-rich nuclear protein 2	3.41874
TWIST1	twist family bHLH transcription factor 1	3.40559
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	3.40549
ARID5B	AT rich interactive domain 5B (MRF1-like)	3.40465
HTRA1	HtrA serine peptidase 1	3.39003
FZD1	frizzled class receptor 1	3.38788
IL10RA	interleukin 10 receptor, alpha	3.38744
NCF2	neutrophil cytosolic factor 2	3.3861
ZNF362	zinc finger protein 362	3.38411
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	3.38323
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	3.38048
CIRSR	corepressor of RBPJ and splicing regulator	3.37881
UNC13A	unc-13 homolog A (C. elegans)	3.37757
EPN2	epsin 2	3.37356
KHDC4	KH domain containing 4, pre-mRNA splicing factor	3.37076
ELAVL3	ELAV like neuron-specific RNA binding protein 3	3.36665
SQOR	sulfide quinone oxidoreductase	3.35935
ACKR3	atypical chemokine receptor 3	3.35405
PLEC	plectin	3.35268
AIRIM	AFG2 interacting ribosome maturation factor	3.35189
CCRL2	chemokine (C-C motif) receptor-like 2	3.3491
CES2	carboxylesterase 2	3.34821
BACE1	beta-site APP-cleaving enzyme 1	3.34652
HDAC7	histone deacetylase 7	3.3454
PLP2	proteolipid protein 2 (colonic epithelium-enriched)	3.34377
MMP9	matrix metallopeptidase 9	3.34292
ENPP4	ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)	3.33419
NOPCHAP1	NOP protein chaperone 1	3.33041
TEX14	testis expressed 14	3.33014
KHDRBS2	KH domain containing, RNA binding, signal transduction associated 2	3.32972
RPRM	reprimo, TP53 dependent G2 arrest mediator candidate	3.32765
ORMDL2	ORMDL sphingolipid biosynthesis regulator 2	3.32672
STK10	serine/threonine kinase 10	3.31902
SNIP1	Smad nuclear interacting protein 1	3.31853
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	3.31199
HAUS2	HAUS augmin-like complex, subunit 2	3.31058
RAI14	retinoic acid induced 14	3.30521
SNAI2	snail family zinc finger 2	3.29814
EMC3	ER membrane protein complex subunit 3	3.2887
MAFF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F	3.28824
LYN	LYN proto-oncogene, Src family tyrosine kinase	3.28495
TRIB1	tribbles pseudokinase 1	3.27961
RTN2	reticulon 2	3.27726
RGCC	regulator of cell cycle	3.27553
CRX	cone-rod homeobox	3.27434
TNFSF9	tumor necrosis factor (ligand) superfamily, member 9	3.27366
SPSB1	splA/ryanodine receptor domain and SOCS box containing 1	3.26743
EMC7	ER membrane protein complex subunit 7	3.26694
BEST2	bestrophin 2	3.26655
CDR2L	cerebellar degeneration-related protein 2-like	3.26577
UBQLN2	ubiquilin 2	3.26165
MAN2C1	mannosidase, alpha, class 2C, member 1	3.25711
PTPRK	protein tyrosine phosphatase, receptor type, K	3.24838
SKIL	SKI-like proto-oncogene	3.24518
CD9	CD9 molecule	3.23842
PSTPIP2	proline-serine-threonine phosphatase interacting protein 2	3.23753
GOLT1B	golgi transport 1B	3.2337
ADO	2-aminoethanethiol (cysteamine) dioxygenase	3.2312
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	3.22849
DDR1	discoidin domain receptor tyrosine kinase 1	3.22747
THAP10	THAP domain containing 10	3.22404
ZNF646	zinc finger protein 646	3.22178
SYNPO	synaptopodin	3.21847
ANGPTL2	angiopoietin-like 2	3.21841
STXBP2	syntaxin binding protein 2	3.2175
CBR1	carbonyl reductase 1	3.2173
STON1	stonin 1	3.21517
GPN2	GPN-loop GTPase 2	3.19798
NSUN3	NOP2/Sun domain family, member 3	3.19334
MAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog	3.19167
TOMM34	translocase of outer mitochondrial membrane 34	3.1891
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4A	3.17706
BBC3	BCL2 binding component 3	3.17546
RAB11FIP2	RAB11 family interacting protein 2 (class I)	3.17169
ZSCAN9	zinc finger and SCAN domain containing 9	3.17012
CHP2	calcineurin-like EF-hand protein 2	3.16951
XRCC2	X-ray repair complementing defective repair in Chinese hamster cells 2	3.16671
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	3.16304
SERINC1	serine incorporator 1	3.16237
SMG8	SMG8 nonsense mediated mRNA decay factor	3.16183
CAMK1D	calcium/calmodulin-dependent protein kinase ID	3.16011
RUSC2	RUN and SH3 domain containing 2	3.15908
TES	testin LIM domain protein	3.15803
MSI1	musashi RNA-binding protein 1	3.15703
SYP	synaptophysin	3.15345
TMEM212	transmembrane protein 212	3.15264
CCDC71	coiled-coil domain containing 71	3.14601
RTL8A	retrotransposon Gag like 8A	3.14448
ROM1	retinal outer segment membrane protein 1	3.14112
DBF4B	DBF4 zinc finger B	3.13856
IER5	immediate early response 5	3.13667
GPER1	G protein-coupled estrogen receptor 1	3.13506
CAPN1	calpain 1, (mu/I) large subunit	3.13224
CRBN	cereblon	3.13138
ASCC3	activating signal cointegrator 1 complex subunit 3	3.12657
YJU2B	YJU2 splicing factor homolog B	3.12383
THSD4	thrombospondin, type I, domain containing 4	3.12232
DUSP11	dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)	3.12198
NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	3.1201
RALB	v-ral simian leukemia viral oncogene homolog B	3.11832
VAV1	vav 1 guanine nucleotide exchange factor	3.11695
TMEM59	transmembrane protein 59	3.1132
PPM1E	protein phosphatase, Mg2+/Mn2+ dependent, 1E	3.11082
TLK2	tousled-like kinase 2	3.10657
BAMBI	BMP and activin membrane-bound inhibitor	3.10516
SLC6A3	solute carrier family 6 (neurotransmitter transporter), member 3	3.10443
THBD	thrombomodulin	3.09718
LPAR2	lysophosphatidic acid receptor 2	3.09341
FAIM	Fas apoptotic inhibitory molecule	3.09313
H2BC5	H2B clustered histone 5	3.08839
CYP11B2	cytochrome P450, family 11, subfamily B, polypeptide 2	3.08655
VEZT	vezatin, adherens junctions transmembrane protein	3.08652
TACR2	tachykinin receptor 2	3.08644
PPP1R14D	protein phosphatase 1, regulatory (inhibitor) subunit 14D	3.08533
GBX2	gastrulation brain homeobox 2	3.08435
HEATR6	HEAT repeat containing 6	3.07975
NVL	nuclear VCP-like	3.07648
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	3.0764
SCD5	stearoyl-CoA desaturase 5	3.07189
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	3.06979
S100A10	S100 calcium binding protein A10	3.06115
BTG1	B-cell translocation gene 1, anti-proliferative	3.05855
HUNK	hormonally up-regulated Neu-associated kinase	3.05431
GPR87	G protein-coupled receptor 87	3.052
PTPN7	protein tyrosine phosphatase, non-receptor type 7	3.05139
TP53I3	tumor protein p53 inducible protein 3	3.04923
TXNL4B	thioredoxin-like 4B	3.04515
RIC8A	RIC8 guanine nucleotide exchange factor A	3.04442
HSD3B2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	3.03748
ARHGEF17	Rho guanine nucleotide exchange factor (GEF) 17	3.03673
ADGRD2	adhesion G protein-coupled receptor D2	3.03557
GSDME	gasdermin E	3.03491
AMOTL2	angiomotin like 2	3.03082
CAVIN1	caveolae associated protein 1	3.03017
NFKBIL1	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1	3.02589
HECTD3	HECT domain containing E3 ubiquitin protein ligase 3	3.02341
GPATCH8	G patch domain containing 8	3.02111
PTPRS	protein tyrosine phosphatase, receptor type, S	3.02063
KIAA1614	KIAA1614	3.01624
PRPF3	pre-mRNA processing factor 3	3.01528
KCNJ5	potassium channel, inwardly rectifying subfamily J, member 5	3.01503
EIF1B	eukaryotic translation initiation factor 1B	3.01071
CSAD	cysteine sulfinic acid decarboxylase	3.00918
KIFBP	kinesin family binding protein	3.00862
SNX13	sorting nexin 13	3.0053
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	3.00523
IL17RA	interleukin 17 receptor A	3.00489
APOBR	apolipoprotein B receptor	3.0026
GADD45B	growth arrest and DNA-damage-inducible, beta	3.00124
PAGE1	P antigen family, member 1 (prostate associated)	3.0001
CDKL3	cyclin-dependent kinase-like 3	2.99993
ALOX15B	arachidonate 15-lipoxygenase, type B	2.99323
MYO5A	myosin VA (heavy chain 12, myoxin)	2.99107
NDRG1	N-myc downstream regulated 1	2.98831
EPAS1	endothelial PAS domain protein 1	2.98714
HMX1	H6 family homeobox 1	2.98635
OLFM4	olfactomedin 4	2.98619
ACVRL1	activin A receptor type II-like 1	2.98548
RAB38	RAB38, member RAS oncogene family	2.98536
MKNK1	MAP kinase interacting serine/threonine kinase 1	2.98449
CHST5	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5	2.98314
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	2.98215
RRS1	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)	2.97343
LAP3	leucine aminopeptidase 3	2.96567
AMIGO2	adhesion molecule with Ig-like domain 2	2.96319
CARD10	caspase recruitment domain family, member 10	2.96306
SIN3B	SIN3 transcription regulator family member B	2.95977
ABCC10	ATP-binding cassette, sub-family C (CFTR/MRP), member 10	2.95829
WBP4	WW domain binding protein 4	2.95669
IQCC	IQ motif containing C	2.95594
BPNT2	3'(2'), 5'-bisphosphate nucleotidase 2	2.95571
AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4	2.95313
CA7	carbonic anhydrase VII	2.95057
ZNF180	zinc finger protein 180	2.94944
ICAM5	intercellular adhesion molecule 5, telencephalin	2.94655
CAVIN3	caveolae associated protein 3	2.94591
TLR3	toll-like receptor 3	2.94389
DPYSL3	dihydropyrimidinase-like 3	2.94255
FDX1	ferredoxin 1	2.94247
BZW2	basic leucine zipper and W2 domains 2	2.94242
TRIM22	tripartite motif containing 22	2.94205
LPAR3	lysophosphatidic acid receptor 3	2.93925
HLA-E	major histocompatibility complex, class I, E	2.93606
ALX3	ALX homeobox 3	2.9277
PPP1R13L	protein phosphatase 1, regulatory subunit 13 like	2.92744
AP3B2	adaptor-related protein complex 3, beta 2 subunit	2.92728
PRR15L	proline rich 15-like	2.92485
KIR3DL3	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3	2.9223
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	2.91951
SIRPA	signal-regulatory protein alpha	2.91719
ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide	2.91644
IL11	interleukin 11	2.91626
TBC1D17	TBC1 domain family, member 17	2.9158
EFNB1	ephrin-B1	2.91551
HCFC2	host cell factor C2	2.91498
SDK2	sidekick cell adhesion molecule 2	2.91374
MMP24OS	MMP24 opposite strand	2.9129
CLEC1B	C-type lectin domain family 1, member B	2.90509
CAMTA2	calmodulin binding transcription activator 2	2.90486
SERTAD3	SERTA domain containing 3	2.90432
MID2	midline 2	2.90223
FABP2	fatty acid binding protein 2, intestinal	2.90184
KLF7	Kruppel-like factor 7 (ubiquitous)	2.90116
KDM5C	lysine (K)-specific demethylase 5C	2.89934
TYW2	tRNA wybutosine-synthesizing protein 2	2.89888
BRME1	break repair meiotic recombinase recruitment factor 1	2.89803
DIPK2B	divergent protein kinase domain 2B	2.89772
POLH	polymerase (DNA directed), eta	2.89642
ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	2.8963
SPEG	SPEG complex locus	2.89586
DMWD	dystrophia myotonica, WD repeat containing	2.89031
NRP1	neuropilin 1	2.88864
NHLH1	nescient helix loop helix 1	2.88517
GHRH	growth hormone releasing hormone	2.88341
HSPBAP1	HSPB (heat shock 27kDa) associated protein 1	2.8809
EVI2A	ecotropic viral integration site 2A	2.87929
RAB8B	RAB8B, member RAS oncogene family	2.87857
CCNT1	cyclin T1	2.87568
RNFT1-DT	RNFT1 divergent transcript	2.87478
ULK1	unc-51 like autophagy activating kinase 1	2.87458
BTG2	BTG family, member 2	2.87116
ZNF557	zinc finger protein 557	2.86286
ZBTB22	zinc finger and BTB domain containing 22	2.86217
PTP4A3	protein tyrosine phosphatase type IVA, member 3	2.85904
MBD1	methyl-CpG binding domain protein 1	2.85843
PHF20L1	PHD finger protein 20-like 1	2.8581
ZNF611	zinc finger protein 611	2.85724
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	2.85497
PNKP	polynucleotide kinase 3'-phosphatase	2.84769
EGLN3	egl-9 family hypoxia-inducible factor 3	2.84073
SDC4	syndecan 4	2.83972
ZKSCAN3	zinc finger with KRAB and SCAN domains 3	2.8393
RING1	ring finger protein 1	2.83433
DCSTAMP	dendrocyte expressed seven transmembrane protein	2.83273
DKK3	dickkopf WNT signaling pathway inhibitor 3	2.83001
FOXJ3	forkhead box J3	2.82905
XPC	xeroderma pigmentosum, complementation group C	2.82593
SRP19	signal recognition particle 19kDa	2.82466
TNFAIP8L2-SCNM1	TNFAIP8L2-SCNM1 readthrough	2.82367
ADAMTSL2	ADAMTS-like 2	2.82357
CSF3	colony stimulating factor 3 (granulocyte)	2.82328
ELMO3	engulfment and cell motility 3	2.82158
ETV7	ets variant 7	2.82125
MAPK7	mitogen-activated protein kinase 7	2.82034
ZNF276	zinc finger protein 276	2.81628
KHDC1L	KH homology domain containing 1-like	2.816
DEGS1	delta(4)-desaturase, sphingolipid 1	2.81539
MARCHF2	membrane associated ring-CH-type finger 2	2.81491
LOC127933115	uncharacterized LOC127933115	2.81205
NUCB1	nucleobindin 1	2.8101
TRIAP1	TP53 regulated inhibitor of apoptosis 1	2.80667
TRAPPC14	trafficking protein particle complex subunit 14	2.80561
BTG3	BTG family, member 3	2.80527
ESM1	endothelial cell-specific molecule 1	2.80459
RLF	rearranged L-myc fusion	2.80352
GNAT1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	2.80225
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	2.80082
VPS52	vacuolar protein sorting 52 homolog (S. cerevisiae)	2.80059
METTL22	methyltransferase like 22	2.7963
ZNF224	zinc finger protein 224	2.79564
ZC3H12A	zinc finger CCCH-type containing 12A	2.79215
CRMP1	collapsin response mediator protein 1	2.79165
KLHL20	kelch-like family member 20	2.7912
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	2.79022
DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5	2.78717
ANGPT2	angiopoietin 2	2.78509
VPS11	vacuolar protein sorting 11 homolog (S. cerevisiae)	2.78476
ATMIN	ATM interactor	2.78471
MAU2	MAU2 sister chromatid cohesion factor	2.78373
SCN4A	sodium channel, voltage gated, type IV alpha subunit	2.78133
AOX1	aldehyde oxidase 1	2.77885
EFR3B	EFR3 homolog B (S. cerevisiae)	2.7765
MYCL	v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog	2.77299
CCL1	chemokine (C-C motif) ligand 1	2.77295
SAYSD1	SAYSVFN motif domain containing 1	2.76948
OSER1	oxidative stress responsive serine-rich 1	2.76595
RAB3B	RAB3B, member RAS oncogene family	2.76572
KDM6B	lysine (K)-specific demethylase 6B	2.76487
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	2.76425
MSR1	macrophage scavenger receptor 1	2.76404
AGRP	agouti related neuropeptide	2.76222
STEAP1B	STEAP family member 1B	2.7617
COL7A1	collagen, type VII, alpha 1	2.76091
STBD1	starch binding domain 1	2.75881
SARM1	sterile alpha and TIR motif containing 1	2.75773
HPS6	Hermansky-Pudlak syndrome 6	2.75737
IKZF4	IKAROS family zinc finger 4 (Eos)	2.75672
CYTH2	cytohesin 2	2.75401
UBE2H	ubiquitin-conjugating enzyme E2H	2.75102
CDH22	cadherin 22, type 2	2.74181
UBXN7	UBX domain protein 7	2.74044
HSF2BP	heat shock transcription factor 2 binding protein	2.74023
AOC1	amine oxidase, copper containing 1	2.73825
FAM110D	family with sequence similarity 110, member D	2.73452
TDP2	tyrosyl-DNA phosphodiesterase 2	2.73227
RIMBP2	RIMS binding protein 2	2.73053
GUCA2A	guanylate cyclase activator 2A (guanylin)	2.727
C3AR1	complement component 3a receptor 1	2.72361
SCGB2A1	secretoglobin, family 2A, member 1	2.72347
ADAM17	ADAM metallopeptidase domain 17	2.723
ELMO2	engulfment and cell motility 2	2.71981
SFRP5	secreted frizzled-related protein 5	2.71902
EMCN	endomucin	2.71786
MEA1	male-enhanced antigen 1	2.71762
USP3	ubiquitin specific peptidase 3	2.71726
TASL	TLR adaptor interacting with endolysosomal SLC15A4	2.70982
CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2	2.70933
TAF5L	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	2.70876
GPR65	G protein-coupled receptor 65	2.70814
ULBP2	UL16 binding protein 2	2.70784
CASP10	caspase 10, apoptosis-related cysteine peptidase	2.70514
TGFB1	transforming growth factor, beta 1	2.70354
SCN1B	sodium channel, voltage gated, type I beta subunit	2.70326
ERCC5	excision repair cross-complementation group 5	2.70124
CLCN1	chloride channel, voltage-sensitive 1	2.69989
TSHZ2	teashirt zinc finger homeobox 2	2.69915
CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	2.69474
MUC2	mucin 2, oligomeric mucus/gel-forming	2.69211
PROCR	protein C receptor, endothelial	2.69207
RNF13	ring finger protein 13	2.68977
NOTCH4	notch 4	2.68951
ZNF816	zinc finger protein 816	2.68708
ZNF7	zinc finger protein 7	2.6868
NPTX2	neuronal pentraxin II	2.68673
KIR3DL2	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2	2.6843
CD52	CD52 molecule	2.68195
EXT1	exostosin glycosyltransferase 1	2.6777
DSE	dermatan sulfate epimerase	2.67579
KDR	kinase insert domain receptor	2.67398
APH1B	APH1B gamma secretase subunit	2.67132
TEAD3	TEA domain family member 3	2.67129
PLPP1	phospholipid phosphatase 1	2.67017
CRLF2	cytokine receptor-like factor 2	2.66826
LOC102725023	killer cell immunoglobulin-like receptor 2DS3 allele 0020101	2.66779
MIDEAS	mitotic deacetylase associated SANT domain protein	2.66589
ACTL8	actin-like 8	2.66567
ZNF394	zinc finger protein 394	2.66494
ADAM30	ADAM metallopeptidase domain 30	2.66457
CLIC5	chloride intracellular channel 5	2.66435
H2BC4	H2B clustered histone 4	2.66294
PORCN	porcupine homolog (Drosophila)	2.66167
CEMP1	cementum protein 1	2.65943
H2BC9	H2B clustered histone 9	2.65938
KCTD17	potassium channel tetramerization domain containing 17	2.65789
NHLH2	nescient helix loop helix 2	2.65722
TKTL1	transketolase-like 1	2.65618
ADRB2	adrenoceptor beta 2, surface	2.65341
OPN1MW3	opsin 1, medium wave sensitive 3	2.65226
ZNF574	zinc finger protein 574	2.65123
PLAUR	plasminogen activator, urokinase receptor	2.65044
GJB5	gap junction protein, beta 5, 31.1kDa	2.65007
EID1	EP300 interacting inhibitor of differentiation 1	2.64986
ASTE1	asteroid homolog 1 (Drosophila)	2.64759
TRIM38	tripartite motif containing 38	2.64606
DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2	2.64396
IRX4	iroquois homeobox 4	2.64285
SLC30A1	solute carrier family 30 (zinc transporter), member 1	2.64276
HSPA1B	heat shock 70kDa protein 1B	2.64258
PRRG2	proline rich Gla (G-carboxyglutamic acid) 2	2.64252
PIP5K1A	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	2.64232
BAX	BCL2-associated X protein	2.64087
ANXA11	annexin A11	2.64059
CYP17A1	cytochrome P450, family 17, subfamily A, polypeptide 1	2.63803
PIK3IP1	phosphoinositide-3-kinase interacting protein 1	2.63594
LOC102723713	TP53-target gene 3 protein	2.63554
CREBL2	cAMP responsive element binding protein-like 2	2.63531
COL4A6	collagen, type IV, alpha 6	2.63426
TMEM143	transmembrane protein 143	2.63414
SSTR3	somatostatin receptor 3	2.63298
ZNF467	zinc finger protein 467	2.63082
CHIT1	chitinase 1 (chitotriosidase)	2.62797
THBS3	thrombospondin 3	2.6255
DSTYK	dual serine/threonine and tyrosine protein kinase	2.62544
LIN37	lin-37 DREAM MuvB core complex component	2.62533
PSG5	pregnancy specific beta-1-glycoprotein 5	2.62369
ALDH1A3	aldehyde dehydrogenase 1 family, member A3	2.62343
ARSA	arylsulfatase A	2.61885
ZNF500	zinc finger protein 500	2.61833
CDIP1	cell death-inducing p53 target 1	2.61553
ZNF331	zinc finger protein 331	2.61502
CTNNAL1	catenin (cadherin-associated protein), alpha-like 1	2.61267
ARHGAP25	Rho GTPase activating protein 25	2.6122
ZNF35	zinc finger protein 35	2.61195
EML3	echinoderm microtubule associated protein like 3	2.60806
GRB7	growth factor receptor-bound protein 7	2.60534
PCDH12	protocadherin 12	2.60496
SAA2	serum amyloid A2	2.60405
CD177	CD177 molecule	2.60384
MAP2K1	mitogen-activated protein kinase kinase 1	2.60361
FOSL2	FOS-like antigen 2	2.60162
SLC15A3	solute carrier family 15 (oligopeptide transporter), member 3	2.59947
PSG7	pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)	2.59859
MOSPD1	motile sperm domain containing 1	2.59761
CDK9	cyclin-dependent kinase 9	2.59722
ZFR2	zinc finger RNA binding protein 2	2.5955
CDCP1	CUB domain containing protein 1	2.59543
TBCC	tubulin folding cofactor C	2.59522
MAPK8	mitogen-activated protein kinase 8	2.59489
PCDH8	protocadherin 8	2.59168
ARL4D	ADP-ribosylation factor-like 4D	2.59104
IL2RA	interleukin 2 receptor, alpha	2.59031
ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	2.58941
ACE	angiotensin I converting enzyme	2.58548
GBE1	glucan (1,4-alpha-), branching enzyme 1	2.5848
EOGT	EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase	2.58435
RTL8C	retrotransposon Gag like 8C	2.58156
HECA	headcase homolog (Drosophila)	2.58061
KIR2DS2	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2	2.57922
WRNIP1	Werner helicase interacting protein 1	2.57882
QRICH1	glutamine-rich 1	2.5782
ZNF155	zinc finger protein 155	2.57772
PTCD2	pentatricopeptide repeat domain 2	2.57679
SCHIP1	schwannomin interacting protein 1	2.56926
KLHL21	kelch-like family member 21	2.56919
MECOM	MDS1 and EVI1 complex locus	2.56798
DLGAP4	discs, large (Drosophila) homolog-associated protein 4	2.56748
CAV1	caveolin 1, caveolae protein, 22kDa	2.5668
XCL1	chemokine (C motif) ligand 1	2.56671
TEK	TEK tyrosine kinase, endothelial	2.56627
TMEM35A	transmembrane protein 35A	2.5658
MAGEA8	melanoma antigen family A8	2.56578
TRIM45	tripartite motif containing 45	2.56392
ESR2	estrogen receptor 2 (ER beta)	2.56354
NOCT	nocturnin	2.56123
FMNL1	formin-like 1	2.56085
ACYP2	acylphosphatase 2, muscle type	2.56049
MDM2	MDM2 proto-oncogene, E3 ubiquitin protein ligase	2.56027
CACNB3	calcium channel, voltage-dependent, beta 3 subunit	2.55946
GPAA1	glycosylphosphatidylinositol anchor attachment 1	2.5593
PSMB10	proteasome (prosome, macropain) subunit, beta type, 10	2.55917
ZNF219	zinc finger protein 219	2.5589
CRYBB1	crystallin, beta B1	2.55779
CPLX3	complexin 3	2.55777
MAPK13	mitogen-activated protein kinase 13	2.55667
PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	2.5557
PLCH2	phospholipase C, eta 2	2.55419
MUC13	mucin 13, cell surface associated	2.55395
CALCRL	calcitonin receptor-like	2.55228
RASA2	RAS p21 protein activator 2	2.55047
ZNF222	zinc finger protein 222	2.54972
WDR26	WD repeat domain 26	2.5475
KLHL24	kelch-like family member 24	2.5459
ADAMDEC1	ADAM-like, decysin 1	2.54298
CEMIP2	cell migration inducing hyaluronidase 2	2.54033
BDKRB1	bradykinin receptor B1	2.53958
KLRB1	killer cell lectin-like receptor subfamily B, member 1	2.53811
SLC4A1AP	solute carrier family 4 (anion exchanger), member 1, adaptor protein	2.53605
ZNF223	zinc finger protein 223	2.53551
GM2A	GM2 ganglioside activator	2.53397
PDLIM7	PDZ and LIM domain 7 (enigma)	2.53314
ATOSB	atos homolog B	2.53135
CATSPER2	cation channel, sperm associated 2	2.52664
HBEGF	heparin-binding EGF-like growth factor	2.52628
ANKRD11	ankyrin repeat domain 11	2.52614
GREM1	gremlin 1, DAN family BMP antagonist	2.52608
SCN3A	sodium channel, voltage gated, type III alpha subunit	2.52592
CYCS	cytochrome c, somatic	2.52527
LOC124906280	uncharacterized LOC124906280	2.52455
RSF1	remodeling and spacing factor 1	2.52441
SH2D3A	SH2 domain containing 3A	2.52342
SLC25A28	solute carrier family 25 (mitochondrial iron transporter), member 28	2.51633
WLS	wntless Wnt ligand secretion mediator	2.51545
TBX5	T-box 5	2.51529
TLE3	transducin-like enhancer of split 3	2.51384
SHARPIN	SHANK-associated RH domain interactor	2.5135
OSGIN1	oxidative stress induced growth inhibitor 1	2.51336
GPSM3	G-protein signaling modulator 3	2.5124
RNLS	renalase, FAD-dependent amine oxidase	2.51237
GTF2B	general transcription factor IIB	2.51202
PPP1R2C	PPP1R2C family member C	2.51126
MEF2D	myocyte enhancer factor 2D	2.50971
ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	2.50928
ROGDI	rogdi homolog (Drosophila)	2.50877
BAG3	BCL2-associated athanogene 3	2.50769
RAD52	RAD52 homolog (S. cerevisiae)	2.50592
FOXD1	forkhead box D1	2.5049
SLC7A10	solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10	2.5035
SMAD6	SMAD family member 6	2.50348
CCDC57	coiled-coil domain containing 57	2.50307
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	2.50158
MAGEA11	melanoma antigen family A11	2.50059
G6PC2	glucose-6-phosphatase, catalytic, 2	2.49497
SORBS3	sorbin and SH3 domain containing 3	2.49408
CD44	CD44 molecule (Indian blood group)	2.49285
VSX1	visual system homeobox 1	2.49115
ST18	suppression of tumorigenicity 18, zinc finger	2.49059
CHRNE	cholinergic receptor, nicotinic, epsilon (muscle)	2.49052
DNAH2	dynein, axonemal, heavy chain 2	2.48975
METTL25B	methyltransferase like 25B	2.48951
SPIN2A	spindlin family, member 2A	2.48782
SLC1A7	solute carrier family 1 (glutamate transporter), member 7	2.48619
ZNF14	zinc finger protein 14	2.48611
PCDH1	protocadherin 1	2.48577
MPC2	mitochondrial pyruvate carrier 2	2.48539
ACTR8	ARP8 actin-related protein 8 homolog (yeast)	2.48425
RAB21	RAB21, member RAS oncogene family	2.48385
OSTF1	osteoclast stimulating factor 1	2.48357
ZG16	zymogen granule protein 16	2.48296
ARNT2	aryl-hydrocarbon receptor nuclear translocator 2	2.48244
DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	2.48224
RBM48	RNA binding motif protein 48	2.48101
GNL1	guanine nucleotide binding protein-like 1	2.48061
ADGRL4	adhesion G protein-coupled receptor L4	2.47886
BARX1	BARX homeobox 1	2.47858
RIN2	Ras and Rab interactor 2	2.47684
ADAM15	ADAM metallopeptidase domain 15	2.47526
HABP4	hyaluronan binding protein 4	2.47476
RGS16	regulator of G-protein signaling 16	2.47377
PLEKHM2	pleckstrin homology domain containing, family M (with RUN domain) member 2	2.47251
NTAN1	N-terminal asparagine amidase	2.47194
TRIM21	tripartite motif containing 21	2.46666
DNAAF3	dynein, axonemal, assembly factor 3	2.4662
KLHL36	kelch-like family member 36	2.46586
NME8	NME/NM23 family member 8	2.46481
ZBTB7A	zinc finger and BTB domain containing 7A	2.46458
DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	2.46376
GNAT2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	2.45981
RRAS	related RAS viral (r-ras) oncogene homolog	2.45939
CELF3	CUGBP, Elav-like family member 3	2.45908
CLCA1	chloride channel accessory 1	2.45852
CCL2	chemokine (C-C motif) ligand 2	2.45582
TEX11	testis expressed 11	2.45528
TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	2.45291
GBA1	glucosylceramidase beta 1	2.45216
KLKB1	kallikrein B, plasma (Fletcher factor) 1	2.45097
BNIP2	BCL2/adenovirus E1B 19kDa interacting protein 2	2.45077
JAG1	jagged 1	2.44928
PSMB8	proteasome (prosome, macropain) subunit, beta type, 8	2.44898
OPRD1	opioid receptor, delta 1	2.4484
IL15RA	interleukin 15 receptor, alpha	2.44626
RAI2	retinoic acid induced 2	2.44507
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	2.443
RAPGEF4	Rap guanine nucleotide exchange factor (GEF) 4	2.44259
RASAL2	RAS protein activator like 2	2.44211
PRKACG	protein kinase, cAMP-dependent, catalytic, gamma	2.44082
CFB	complement factor B	2.44046
PLEK2	pleckstrin 2	2.4372
PLEKHO2	pleckstrin homology domain containing, family O member 2	2.43712
PTPN4	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)	2.4368
MUC1	mucin 1, cell surface associated	2.43539
DLK2	delta-like 2 homolog (Drosophila)	2.4344
PRAMEF10	PRAME family member 10	2.42532
IMPG2	interphotoreceptor matrix proteoglycan 2	2.42392
GPR183	G protein-coupled receptor 183	2.42319
RHEX	regulator of hemoglobinization and erythroid cell expansion	2.42305
PDE9A	phosphodiesterase 9A	2.42101
SNAPC2	small nuclear RNA activating complex, polypeptide 2, 45kDa	2.42022
TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B	2.41934
TMSB15B	thymosin beta 15B	2.41929
SRD5A2	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)	2.41919
PKM	pyruvate kinase, muscle	2.41673
PSG4	pregnancy specific beta-1-glycoprotein 4	2.41589
CASP2	caspase 2, apoptosis-related cysteine peptidase	2.4151
NUDT11	nudix (nucleoside diphosphate linked moiety X)-type motif 11	2.41446
CCSER2	coiled-coil serine-rich protein 2	2.41353
GJA1	gap junction protein, alpha 1, 43kDa	2.41293
TRIM23	tripartite motif containing 23	2.41284
CAB39L	calcium binding protein 39-like	2.41183
CHRM2	cholinergic receptor, muscarinic 2	2.40883
FRMD4B	FERM domain containing 4B	2.40846
HOXD3	homeobox D3	2.40811
MYOZ3	myozenin 3	2.40803
BICD1	bicaudal D homolog 1 (Drosophila)	2.40637
FGFR2	fibroblast growth factor receptor 2	2.40635
KIAA0408	KIAA0408	2.40612
ZNF205	zinc finger protein 205	2.40496
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	2.40405
PPP1R16B	protein phosphatase 1, regulatory subunit 16B	2.40381
PLAG1	pleiomorphic adenoma gene 1	2.40369
PROZ	protein Z, vitamin K-dependent plasma glycoprotein	2.4036
FGF18	fibroblast growth factor 18	2.40172
NKX6-1	NK6 homeobox 1	2.4009
SULT4A1	sulfotransferase family 4A, member 1	2.39877
PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	2.3986
MYH9	myosin, heavy chain 9, non-muscle	2.3972
SLC9A3	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3	2.39483
RIOK3	RIO kinase 3	2.39197
HPCAL4	hippocalcin like 4	2.39179
ITGA9	integrin, alpha 9	2.39162
BDKRB2	bradykinin receptor B2	2.39121
SMNDC1	survival motor neuron domain containing 1	2.39073
APOL6	apolipoprotein L, 6	2.39034
GIMAP6	GTPase, IMAP family member 6	2.39014
ANXA8L1	annexin A8-like 1	2.38977
VCPIP1	valosin containing protein (p97)/p47 complex interacting protein 1	2.38873
WDR5B	WD repeat domain 5B	2.38838
BICRA	BRD4 interacting chromatin remodeling complex associated protein	2.3871
CFLAR	CASP8 and FADD-like apoptosis regulator	2.38564
THSD7A	thrombospondin, type I, domain containing 7A	2.3855
MMP28	matrix metallopeptidase 28	2.38287
VPS35L	VPS35 endosomal protein sorting factor like	2.38282
COQ8B	coenzyme Q8B	2.38252
ARMCX5-GPRASP2	ARMCX5-GPRASP2 readthrough	2.38128
CYP11B1	cytochrome P450, family 11, subfamily B, polypeptide 1	2.38116
IGFALS	insulin-like growth factor binding protein, acid labile subunit	2.38083
GPR63	G protein-coupled receptor 63	2.37981
TMEM19	transmembrane protein 19	2.37671
PLXNB1	plexin B1	2.37604
OLFML2A	olfactomedin-like 2A	2.37582
TFIP11	tuftelin interacting protein 11	2.37536
MAN2B1	mannosidase, alpha, class 2B, member 1	2.37406
SCARF1	scavenger receptor class F, member 1	2.37355
RIPK4	receptor-interacting serine-threonine kinase 4	2.37265
CLCF1	cardiotrophin-like cytokine factor 1	2.3725
MAPKBP1	mitogen-activated protein kinase binding protein 1	2.37212
COLQ	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	2.36988
BCAM	basal cell adhesion molecule (Lutheran blood group)	2.36988
RNF115	ring finger protein 115	2.36931
ZNF286A	zinc finger protein 286A	2.3684
TWF2	twinfilin actin binding protein 2	2.36818
CST8	cystatin 8 (cystatin-related epididymal specific)	2.36808
SRP14	signal recognition particle 14kDa (homologous Alu RNA binding protein)	2.36685
TRPM6	transient receptor potential cation channel, subfamily M, member 6	2.36684
OR2C1	olfactory receptor, family 2, subfamily C, member 1	2.36644
OR7C2	olfactory receptor, family 7, subfamily C, member 2	2.36548
FLT3LG	fms-related tyrosine kinase 3 ligand	2.36517
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	2.36276
IL18RAP	interleukin 18 receptor accessory protein	2.36213
PFDN1	prefoldin subunit 1	2.3617
IRS2	insulin receptor substrate 2	2.36146
NUAK1	NUAK family, SNF1-like kinase, 1	2.3598
GJA8	gap junction protein, alpha 8, 50kDa	2.35914
SLC39A2	solute carrier family 39 (zinc transporter), member 2	2.3586
MYNN	myoneurin	2.35844
RIN1	Ras and Rab interactor 1	2.35787
NEO1	neogenin 1	2.35611
SLC28A2	solute carrier family 28 (concentrative nucleoside transporter), member 2	2.35589
TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	2.35379
RGS10	regulator of G-protein signaling 10	2.35368
PPP2R3A	protein phosphatase 2, regulatory subunit B'', alpha	2.35303
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	2.35301
RBM22	RNA binding motif protein 22	2.353
SLC10A3	solute carrier family 10, member 3	2.35278
KIR2DL4	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4	2.35183
COG7	component of oligomeric golgi complex 7	2.35094
MSRA	methionine sulfoxide reductase A	2.35002
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	2.34839
APOBEC3G	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G	2.34663
CD47	CD47 molecule	2.34631
CCL7	chemokine (C-C motif) ligand 7	2.34324
TSPAN12	tetraspanin 12	2.3395
L3MBTL1	l(3)mbt-like 1 (Drosophila)	2.338
ISCU	iron-sulfur cluster assembly enzyme	2.3377
ANGPTL4	angiopoietin-like 4	2.33605
HCK	HCK proto-oncogene, Src family tyrosine kinase	2.33582
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	2.33545
NABP1	nucleic acid binding protein 1	2.33416
ARHGAP33	Rho GTPase activating protein 33	2.33386
ZNF226	zinc finger protein 226	2.33377
BMP1	bone morphogenetic protein 1	2.33248
LAMA5	laminin, alpha 5	2.32966
TIMM50	translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)	2.32789
AVPI1	arginine vasopressin-induced 1	2.32682
GABRD	gamma-aminobutyric acid (GABA) A receptor, delta	2.32657
GPRC5D	G protein-coupled receptor, class C, group 5, member D	2.32649
NPFFR1	neuropeptide FF receptor 1	2.32595
KBTBD2	kelch repeat and BTB (POZ) domain containing 2	2.32494
DNTTIP2	deoxynucleotidyltransferase, terminal, interacting protein 2	2.32493
PCDHA10	protocadherin alpha 10	2.3242
NGF	nerve growth factor (beta polypeptide)	2.32188
PLD3	phospholipase D family, member 3	2.32182
LHB	luteinizing hormone beta polypeptide	2.32164
SLAMF8	SLAM family member 8	2.32087
KIF21B	kinesin family member 21B	2.31773
MFGE8	milk fat globule-EGF factor 8 protein	2.31746
RFX5	regulatory factor X, 5 (influences HLA class II expression)	2.31706
TMEM259	transmembrane protein 259	2.31658
ZNG1A	Zn regulated GTPase metalloprotein activator 1A	2.31434
TRPM4	transient receptor potential cation channel, subfamily M, member 4	2.3132
TMEM115	transmembrane protein 115	2.31226
DNAJA3	DnaJ (Hsp40) homolog, subfamily A, member 3	2.31188
PMS2	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	2.31075
MMAB	methylmalonic aciduria (cobalamin deficiency) cblB type	2.30716
LDOC1	leucine zipper, down-regulated in cancer 1	2.30689
GLI1	GLI family zinc finger 1	2.30614
ADAM23	ADAM metallopeptidase domain 23	2.30539
JOSD1	Josephin domain containing 1	2.30492
OXCT2	3-oxoacid CoA transferase 2	2.30429
NTF3	neurotrophin 3	2.30413
HINFP	histone H4 transcription factor	2.30387
CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit	2.30357
PRX	periaxin	2.30345
ZNF212	zinc finger protein 212	2.30196
MAP3K11	mitogen-activated protein kinase kinase kinase 11	2.30134
PHLDA2	pleckstrin homology-like domain, family A, member 2	2.29747
SNX15	sorting nexin 15	2.29742
PRSS21	protease, serine, 21 (testisin)	2.29734
ATP8B1	ATPase, aminophospholipid transporter, class I, type 8B, member 1	2.29683
DOHH	deoxyhypusine hydroxylase/monooxygenase	2.29676
TJAP1	tight junction associated protein 1 (peripheral)	2.296
PIWIL2	piwi-like RNA-mediated gene silencing 2	2.29536
ELL2	elongation factor, RNA polymerase II, 2	2.2951
KATNIP	katanin interacting protein	2.29498
ZBTB38	zinc finger and BTB domain containing 38	2.29408
ATG16L1	autophagy related 16-like 1 (S. cerevisiae)	2.29372
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	2.29354
MZF1	myeloid zinc finger 1	2.2918
SPSB3	splA/ryanodine receptor domain and SOCS box containing 3	2.2914
INKA2	inka box actin regulator 2	2.29068
PDCL	phosducin-like	2.29063
PSG9	pregnancy specific beta-1-glycoprotein 9	2.2898
GIPC1	GIPC PDZ domain containing family, member 1	2.28852
MYOF	myoferlin	2.28745
KIR3DL1	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1	2.28656
FASLG	Fas ligand (TNF superfamily, member 6)	2.28594
VEGFA	vascular endothelial growth factor A	2.28576
RBP3	retinol binding protein 3, interstitial	2.28571
MMP1	matrix metallopeptidase 1	2.28513
LHFPL6	LHFPL tetraspan subfamily member 6	2.28483
INPP5K	inositol polyphosphate-5-phosphatase K	2.28449
ZNF197	zinc finger protein 197	2.28334
APOL3	apolipoprotein L, 3	2.28301
PXDN	peroxidasin	2.28173
RASA4	RAS p21 protein activator 4	2.28162
SAP30BP	SAP30 binding protein	2.28093
OGA	O-GlcNAcase	2.28012
EEF1AKMT4-ECE2	EEF1AKMT4-ECE2 readthrough	2.27892
GMFG	glia maturation factor, gamma	2.27884
ANKRD10	ankyrin repeat domain 10	2.27836
LPCAT4	lysophosphatidylcholine acyltransferase 4	2.27558
BRD2	bromodomain containing 2	2.27532
KIR2DS4	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4	2.27517
MEP1B	meprin A, beta	2.27506
GPR45	G protein-coupled receptor 45	2.2747
CDIPT	CDP-diacylglycerol--inositol 3-phosphatidyltransferase	2.27454
AKAP8L	A kinase (PRKA) anchor protein 8-like	2.27437
FURIN	furin (paired basic amino acid cleaving enzyme)	2.27412
ZBTB17	zinc finger and BTB domain containing 17	2.27411
RND3	Rho family GTPase 3	2.27364
ITFG2	integrin alpha FG-GAP repeat containing 2	2.27213
MBOAT7	membrane bound O-acyltransferase domain containing 7	2.27121
PPARD	peroxisome proliferator-activated receptor delta	2.26998
CYP27B1	cytochrome P450, family 27, subfamily B, polypeptide 1	2.26814
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	2.26806
DCLRE1B	DNA cross-link repair 1B	2.26736
ZNF227	zinc finger protein 227	2.26668
WHR1	winged helix repair factor 1	2.26647
RNF186	ring finger protein 186	2.26618
SPATA7	spermatogenesis associated 7	2.26523
RIPPLY2-CYB5R4	RIPPLY2-CYB5R4 readthrough	2.26513
EGFL8	EGF-like-domain, multiple 8	2.26432
TSC2	tuberous sclerosis 2	2.26423
MBTD1	mbt domain containing 1	2.26316
HOXC13	homeobox C13	2.26287
IGSF6	immunoglobulin superfamily, member 6	2.26285
SLC8B1	solute carrier family 8 (sodium/lithium/calcium exchanger), member B1	2.26267
ZSCAN16	zinc finger and SCAN domain containing 16	2.2623
H2BC11	H2B clustered histone 11	2.26127
PDIA3	protein disulfide isomerase family A, member 3	2.26032
SLC30A4	solute carrier family 30 (zinc transporter), member 4	2.2586
PRKRIP1	PRKR interacting protein 1 (IL11 inducible)	2.2583
TOE1	target of EGR1, member 1 (nuclear)	2.25798
MAGEH1	melanoma antigen family H1	2.25789
ARSD	arylsulfatase D	2.2573
ZSCAN26	zinc finger and SCAN domain containing 26	2.25704
AIFM2	apoptosis-inducing factor, mitochondrion-associated, 2	2.25507
UTP25	UTP25 small subunit processome component	2.25483
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	2.25295
SPNS1	spinster homolog 1 (Drosophila)	2.25229
HAND2	heart and neural crest derivatives expressed 2	2.25197
WDR47	WD repeat domain 47	2.2503
RBKS	ribokinase	2.24979
LY6G6C	lymphocyte antigen 6 complex, locus G6C	2.2481
GCC1	GRIP and coiled-coil domain containing 1	2.24795
LPXN	leupaxin	2.2477
MSLN	mesothelin	2.24658
TOR4A	torsin family 4, member A	2.24627
SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	2.24531
LTK	leukocyte receptor tyrosine kinase	2.24059
DGKB	diacylglycerol kinase, beta 90kDa	2.24055
KCNAB1	potassium channel, voltage gated subfamily A regulatory beta subunit 1	2.24037
RNF40	ring finger protein 40, E3 ubiquitin protein ligase	2.24013
POLR3C	polymerase (RNA) III (DNA directed) polypeptide C (62kD)	2.23644
KANK3	KN motif and ankyrin repeat domains 3	2.23359
HRK	harakiri, BCL2 interacting protein	2.2326
GTPBP8	GTP-binding protein 8 (putative)	2.23255
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	2.23245
MRPL57	mitochondrial ribosomal protein L57	2.23134
LOC102724023	ES1 protein homolog, mitochondrial	2.23121
RTP4	receptor (chemosensory) transporter protein 4	2.22894
LYRM2	LYR motif containing 2	2.22891
KDM6A	lysine (K)-specific demethylase 6A	2.22771
GALNS	galactosamine (N-acetyl)-6-sulfatase	2.22722
LOC124900275	extensin-like	2.22681
TRIT1	tRNA isopentenyltransferase 1	2.22623
GCNT4	glucosaminyl (N-acetyl) transferase 4, core 2	2.22604

decreased expression

Symbol	Name	Standardized Value
ETFB	electron-transfer-flavoprotein, beta polypeptide	-10.0
PSMG1	proteasome (prosome, macropain) assembly chaperone 1	-10.0
RPIA	ribose 5-phosphate isomerase A	-10.0
MELK	maternal embryonic leucine zipper kinase	-10.0
LBR	lamin B receptor	-10.0
PYCR1	pyrroline-5-carboxylate reductase 1	-10.0
HMGA2	high mobility group AT-hook 2	-10.0
MYC	v-myc avian myelocytomatosis viral oncogene homolog	-10.0
PLEKHJ1	pleckstrin homology domain containing, family J member 1	-10.0
PARP1	poly (ADP-ribose) polymerase 1	-9.75982
PCBD1	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	-9.67436
CDC20	cell division cycle 20	-9.56885
TCTN1	tectonic family member 1	-9.36695
POLE2	polymerase (DNA directed), epsilon 2, accessory subunit	-9.32205
PCCB	propionyl CoA carboxylase, beta polypeptide	-9.23603
PLK1	polo-like kinase 1	-8.88475
B4GAT1	beta-1,4-glucuronyltransferase 1	-8.71888
TCERG1	transcription elongation regulator 1	-8.6162
LOC124907782	dual specificity protein phosphatase 22	-8.26324
STMN1	stathmin 1	-8.14657
PGM1	phosphoglucomutase 1	-7.94414
LPGAT1	lysophosphatidylglycerol acyltransferase 1	-7.86826
CCNA2	cyclin A2	-7.85894
AARS1	alanyl-tRNA synthetase 1	-7.67228
SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)	-7.64583
EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1	-7.64552
GET1	guided entry of tail-anchored proteins factor 1	-7.56405
GLOD4	glyoxalase domain containing 4	-7.52164
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	-7.50987
ENOPH1	enolase-phosphatase 1	-7.48386
BLMH	bleomycin hydrolase	-7.36691
SLC25A13	solute carrier family 25 (aspartate/glutamate carrier), member 13	-7.31215
PECR	peroxisomal trans-2-enoyl-CoA reductase	-6.86202
LYPLA1	lysophospholipase I	-6.81294
USP6NL	USP6 N-terminal like	-6.72698
MYBL2	v-myb avian myeloblastosis viral oncogene homolog-like 2	-6.66297
RPS4Y1	ribosomal protein S4, Y-linked 1	-6.64344
NUP85	nucleoporin 85kDa	-6.63092
STAMBP	STAM binding protein	-6.61413
LAGE3	L antigen family, member 3	-6.58004
CDK4	cyclin-dependent kinase 4	-6.57276
MRPL12	mitochondrial ribosomal protein L12	-6.54596
G3BP1	GTPase activating protein (SH3 domain) binding protein 1	-6.52385
LSM6	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	-6.46684
SOAT2	sterol O-acyltransferase 2	-6.44945
NT5DC2	5'-nucleotidase domain containing 2	-6.39519
MRPS2	mitochondrial ribosomal protein S2	-6.39417
UGDH	UDP-glucose 6-dehydrogenase	-6.3736
POLR2I	polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa	-6.21132
TOP2A	topoisomerase (DNA) II alpha 170kDa	-6.18707
NCK2	NCK adaptor protein 2	-6.10822
ANXA7	annexin A7	-6.04837
EPB41L2	erythrocyte membrane protein band 4.1-like 2	-6.03332
AKR7A2	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)	-5.99718
DCK	deoxycytidine kinase	-5.95647
NNT	nicotinamide nucleotide transhydrogenase	-5.9466
DHX29	DEAH (Asp-Glu-Ala-His) box polypeptide 29	-5.92181
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	-5.9208
CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)	-5.90794
TRAPPC3	trafficking protein particle complex 3	-5.70807
FGFR4	fibroblast growth factor receptor 4	-5.70488
TIMM9	translocase of inner mitochondrial membrane 9 homolog (yeast)	-5.69585
RFC2	replication factor C (activator 1) 2, 40kDa	-5.68534
POLR1A	polymerase (RNA) I polypeptide A, 194kDa	-5.62928
PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	-5.54066
CHEK2	checkpoint kinase 2	-5.50126
AMDHD2	amidohydrolase domain containing 2	-5.49748
PHGDH	phosphoglycerate dehydrogenase	-5.45806
NIPSNAP1	nipsnap homolog 1 (C. elegans)	-5.4539
HACD3	3-hydroxyacyl-CoA dehydratase 3	-5.39067
RBM14-RBM4	RBM14-RBM4 readthrough	-5.36989
PLS1	plastin 1	-5.3618
KIF14	kinesin family member 14	-5.33799
MAP3K4	mitogen-activated protein kinase kinase kinase 4	-5.25819
HSD17B10	hydroxysteroid (17-beta) dehydrogenase 10	-5.25501
HEATR1	HEAT repeat containing 1	-5.22979
FDFT1	farnesyl-diphosphate farnesyltransferase 1	-5.17918
PAICS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	-5.14714
TLCD3A	TLC domain containing 3A	-5.14676
HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	-5.12439
PAFAH1B3	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)	-5.08513
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	-5.03806
CDK1	cyclin-dependent kinase 1	-5.02754
TATDN2	TatD DNase domain containing 2	-5.01933
SLC5A6	solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6	-4.97494
CHMP6	charged multivesicular body protein 6	-4.97314
TFDP1	transcription factor Dp-1	-4.91654
ALG6	ALG6, alpha-1,3-glucosyltransferase	-4.89562
VASH2	vasohibin 2	-4.86738
ARFIP2	ADP-ribosylation factor interacting protein 2	-4.78996
DNM1L	dynamin 1-like	-4.75189
KIF15	kinesin family member 15	-4.73043
TRAK2	trafficking protein, kinesin binding 2	-4.71989
CCNB2	cyclin B2	-4.69772
CCT7	chaperonin containing TCP1, subunit 7 (eta)	-4.65266
ANKRD17	ankyrin repeat domain 17	-4.63927
ITGAE	integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)	-4.63883
CHAF1B	chromatin assembly factor 1, subunit B (p60)	-4.62473
IDH1	isocitrate dehydrogenase 1 (NADP+), soluble	-4.60298
TIMM17B	translocase of inner mitochondrial membrane 17 homolog B (yeast)	-4.60261
SCCPDH	saccharopine dehydrogenase (putative)	-4.59688
PSRC1	proline/serine-rich coiled-coil 1	-4.56712
DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	-4.56675
IDE	insulin-degrading enzyme	-4.54563
TMEM97	transmembrane protein 97	-4.54271
RUVBL1	RuvB-like AAA ATPase 1	-4.54226
ELAVL1	ELAV like RNA binding protein 1	-4.53992
AFG3L2	AFG3-like AAA ATPase 2	-4.53397
SLC35F2	solute carrier family 35, member F2	-4.52711
UBE2C	ubiquitin-conjugating enzyme E2C	-4.516
MSH2	mutS homolog 2	-4.50407
HAT1	histone acetyltransferase 1	-4.50232
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	-4.45466
PCYT2	phosphate cytidylyltransferase 2, ethanolamine	-4.45446
DNMT1	DNA (cytosine-5-)-methyltransferase 1	-4.43956
ANKRD27	ankyrin repeat domain 27 (VPS9 domain)	-4.40473
DCTD	dCMP deaminase	-4.36665
PROS1	protein S (alpha)	-4.36003
GMDS	GDP-mannose 4,6-dehydratase	-4.3241
PPM1H	protein phosphatase, Mg2+/Mn2+ dependent, 1H	-4.32169
MRPL19	mitochondrial ribosomal protein L19	-4.30561
CD320	CD320 molecule	-4.30225
LDHD	lactate dehydrogenase D	-4.29266
CLTA	clathrin, light chain A	-4.24358
XPO1	exportin 1	-4.22856
PEBP1	phosphatidylethanolamine binding protein 1	-4.22133
MSH6	mutS homolog 6	-4.21219
EMID1	EMI domain containing 1	-4.20548
TACC3	transforming, acidic coiled-coil containing protein 3	-4.17534
MTA1	metastasis associated 1	-4.12887
TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	-4.12638
GCAT	glycine C-acetyltransferase	-4.10341
TIMELESS	timeless circadian clock	-4.1002
KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	-4.08347
TPM1	tropomyosin 1 (alpha)	-4.04659
ATP7B	ATPase, Cu++ transporting, beta polypeptide	-4.023
SLC27A5	solute carrier family 27 (fatty acid transporter), member 5	-4.01148
MIS18A	MIS18 kinetochore protein A	-3.98571
VRK2	vaccinia related kinase 2	-3.97803
AHSG	alpha-2-HS-glycoprotein	-3.97561
CDK6	cyclin-dependent kinase 6	-3.97461
CDC25B	cell division cycle 25B	-3.96088
ABL1	ABL proto-oncogene 1, non-receptor tyrosine kinase	-3.94769
ICAM3	intercellular adhesion molecule 3	-3.93013
ANAPC1	anaphase promoting complex subunit 1	-3.92114
CLIC4	chloride intracellular channel 4	-3.86681
STOML2	stomatin (EPB72)-like 2	-3.86607
ABCE1	ATP-binding cassette, sub-family E (OABP), member 1	-3.82733
PHKB	phosphorylase kinase, beta	-3.82581
DDX3Y	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked	-3.8135
PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	-3.80511
AGMAT	agmatine ureohydrolase (agmatinase)	-3.7918
SRMS	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites	-3.76516
MRPS16	mitochondrial ribosomal protein S16	-3.76198
QPRT	quinolinate phosphoribosyltransferase	-3.75814
CLTC	clathrin, heavy chain (Hc)	-3.75771
ERO1A	endoplasmic reticulum oxidoreductase 1 alpha	-3.75467
MCM5	minichromosome maintenance complex component 5	-3.75168
BCL7B	B-cell CLL/lymphoma 7B	-3.74658
SNRPA	small nuclear ribonucleoprotein polypeptide A	-3.74114
SEPHS1	selenophosphate synthetase 1	-3.73415
IFRD2	interferon-related developmental regulator 2	-3.72956
BIRC5	baculoviral IAP repeat containing 5	-3.70957
RSU1	Ras suppressor protein 1	-3.70548
PTGES3	prostaglandin E synthase 3 (cytosolic)	-3.6998
TESC	tescalcin	-3.69955
CCT4	chaperonin containing TCP1, subunit 4 (delta)	-3.69875
ITIH2	inter-alpha-trypsin inhibitor heavy chain 2	-3.6836
APOH	apolipoprotein H (beta-2-glycoprotein I)	-3.6815
POLA1	polymerase (DNA directed), alpha 1, catalytic subunit	-3.67539
EML4	echinoderm microtubule associated protein like 4	-3.67503
ASGR1	asialoglycoprotein receptor 1	-3.66729
KIF2C	kinesin family member 2C	-3.65874
HNRNPF	heterogeneous nuclear ribonucleoprotein F	-3.65785
SNRNP25	small nuclear ribonucleoprotein 25kDa (U11/U12)	-3.651
POLA2	polymerase (DNA directed), alpha 2, accessory subunit	-3.64876
EPRS1	glutamyl-prolyl-tRNA synthetase 1	-3.64482
TIA1	TIA1 cytotoxic granule-associated RNA binding protein	-3.63229
DCPS	decapping enzyme, scavenger	-3.61999
COPZ1	coatomer protein complex, subunit zeta 1	-3.6009
MPZL1	myelin protein zero-like 1	-3.58814
U2SURP	U2 snRNP-associated SURP domain containing	-3.58262
SLC43A1	solute carrier family 43 (amino acid system L transporter), member 1	-3.57713
NUP43	nucleoporin 43kDa	-3.57
HMMR	hyaluronan-mediated motility receptor (RHAMM)	-3.56725
MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)	-3.55915
PYGL	phosphorylase, glycogen, liver	-3.55839
KIF4A	kinesin family member 4A	-3.54452
SLC25A10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	-3.53466
MARCKSL1	MARCKS-like 1	-3.52193
ASPSCR1	alveolar soft part sarcoma chromosome region, candidate 1	-3.50772
CDC6	cell division cycle 6	-3.50505
SPAG4	sperm associated antigen 4	-3.49449
PDS5A	PDS5 cohesin associated factor A	-3.48614
ERBB3	erb-b2 receptor tyrosine kinase 3	-3.48215
ABCD3	ATP-binding cassette, sub-family D (ALD), member 3	-3.48122
UROS	uroporphyrinogen III synthase	-3.4792
FKBP3	FK506 binding protein 3, 25kDa	-3.47757
TXNDC5	thioredoxin domain containing 5 (endoplasmic reticulum)	-3.47077
DEPDC1	DEP domain containing 1	-3.47067
LRRC20	leucine rich repeat containing 20	-3.46342
RRP1B	ribosomal RNA processing 1B	-3.45444
CHMP4B	charged multivesicular body protein 4B	-3.40803
HS2ST1	heparan sulfate 2-O-sulfotransferase 1	-3.39997
XPOT	exportin, tRNA	-3.39904
ACAA1	acetyl-CoA acyltransferase 1	-3.3976
PFAS	phosphoribosylformylglycinamidine synthase	-3.39122
HNRNPM	heterogeneous nuclear ribonucleoprotein M	-3.38731
IMPA2	inositol(myo)-1(or 4)-monophosphatase 2	-3.38707
RBBP4	retinoblastoma binding protein 4	-3.38261
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	-3.3755
CHEK1	checkpoint kinase 1	-3.37544
DONSON	downstream neighbor of SON	-3.37538
CTPS2	CTP synthase 2	-3.3739
CENPX	centromere protein X	-3.37385
TRIP13	thyroid hormone receptor interactor 13	-3.37331
PCNA	proliferating cell nuclear antigen	-3.36884
DAZAP1	DAZ associated protein 1	-3.35013
NENF	neudesin neurotrophic factor	-3.3442
PCDHB11	protocadherin beta 11	-3.34199
NCAPH	non-SMC condensin I complex, subunit H	-3.34126
TMEM109	transmembrane protein 109	-3.33089
APTX	aprataxin	-3.32044
STAP2	signal transducing adaptor family member 2	-3.3199
YARS1	tyrosyl-tRNA synthetase 1	-3.31969
COASY	CoA synthase	-3.3137
SDF2L1	stromal cell-derived factor 2-like 1	-3.30863
LYZ	lysozyme	-3.29728
CASC3	cancer susceptibility candidate 3	-3.27707
HDAC1	histone deacetylase 1	-3.27243
TFB1M	transcription factor B1, mitochondrial	-3.25856
PMPCA	peptidase (mitochondrial processing) alpha	-3.25747
SLC37A4	solute carrier family 37 (glucose-6-phosphate transporter), member 4	-3.25632
SORL1	sortilin-related receptor, L(DLR class) A repeats containing	-3.25191
TIMCC	TIM double twin CX3C motif chaperone	-3.24705
COBL	cordon-bleu WH2 repeat protein	-3.24506
PBK	PDZ binding kinase	-3.24367
HKDC1	hexokinase domain containing 1	-3.2429
HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	-3.24145
VRK1	vaccinia related kinase 1	-3.23791
MCM10	minichromosome maintenance complex component 10	-3.23677
MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	-3.23314
ANAPC15	anaphase promoting complex subunit 15	-3.23185
DHRS2	dehydrogenase/reductase (SDR family) member 2	-3.21608
PAXIP1	PAX interacting (with transcription-activation domain) protein 1	-3.19562
DCXR	dicarbonyl/L-xylulose reductase	-3.1848
ALDOC	aldolase C, fructose-bisphosphate	-3.18325
SLC17A9	solute carrier family 17 (vesicular nucleotide transporter), member 9	-3.17769
SMC4	structural maintenance of chromosomes 4	-3.17394
MUC7	mucin 7, secreted	-3.17223
DHFR	dihydrofolate reductase	-3.17069
PARPBP	PARP1 binding protein	-3.16461
NME4	NME/NM23 nucleoside diphosphate kinase 4	-3.16376
SPC25	SPC25, NDC80 kinetochore complex component	-3.15681
DHRS11	dehydrogenase/reductase (SDR family) member 11	-3.15144
GLRX5	glutaredoxin 5	-3.15056
NCAPG2	non-SMC condensin II complex, subunit G2	-3.14917
LSM7	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)	-3.13259
APOA2	apolipoprotein A-II	-3.1325
HNRNPA3	heterogeneous nuclear ribonucleoprotein A3	-3.12213
C5	complement component 5	-3.11777
YKT6	YKT6 v-SNARE homolog (S. cerevisiae)	-3.11644
HMGN1	high mobility group nucleosome binding domain 1	-3.11641
XPO7	exportin 7	-3.11475
UCHL5	ubiquitin carboxyl-terminal hydrolase L5	-3.10293
AP1AR	adaptor-related protein complex 1 associated regulatory protein	-3.10268
BLM	Bloom syndrome, RecQ helicase-like	-3.10205
FABP5	fatty acid binding protein 5 (psoriasis-associated)	-3.10001
LARP1	La ribonucleoprotein domain family, member 1	-3.09477
LRBA	LPS-responsive vesicle trafficking, beach and anchor containing	-3.09283
CENPA	centromere protein A	-3.09152
RITA1	RBPJ interacting and tubulin associated 1	-3.09074
SNRPD3	small nuclear ribonucleoprotein D3 polypeptide 18kDa	-3.08661
AMBP	alpha-1-microglobulin/bikunin precursor	-3.07486
APOM	apolipoprotein M	-3.07322
PNN	pinin, desmosome associated protein	-3.06706
AURKA	aurora kinase A	-3.06313
CHPT1	choline phosphotransferase 1	-3.06302
CSE1L	CSE1 chromosome segregation 1-like (yeast)	-3.05989
GAS2	growth arrest-specific 2	-3.05931
SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	-3.05651
CEP83	centrosomal protein 83kDa	-3.05551
DNAAF2	dynein, axonemal, assembly factor 2	-3.05246
SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	-3.05061
TMEM147	transmembrane protein 147	-3.04659
CEP192	centrosomal protein 192kDa	-3.04469
MPHOSPH9	M-phase phosphoprotein 9	-3.0436
ICMT	isoprenylcysteine carboxyl methyltransferase	-3.04191
GTF2E2	general transcription factor IIE, polypeptide 2, beta 34kDa	-3.03523
SAA4	serum amyloid A4, constitutive	-3.03264
HSPD1	heat shock 60kDa protein 1 (chaperonin)	-3.03249
DCP2	decapping mRNA 2	-3.03172
SKIC8	SKI8 subunit of superkiller complex	-3.03027
CCNF	cyclin F	-3.0185
UBE2L3	ubiquitin-conjugating enzyme E2L 3	-3.01317
MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	-3.01165
NASP	nuclear autoantigenic sperm protein (histone-binding)	-3.00572
PGAM4	phosphoglycerate mutase family member 4	-2.99856
UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)	-2.99521
PHKA1	phosphorylase kinase, alpha 1 (muscle)	-2.99116
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	-2.99097
PPIF	peptidylprolyl isomerase F	-2.99096
CDC45	cell division cycle 45	-2.98278
NUDCD3	NudC domain containing 3	-2.98216
CCDC86	coiled-coil domain containing 86	-2.97076
NFE2	nuclear factor, erythroid 2	-2.96268
TBC1D10C	TBC1 domain family, member 10C	-2.96191
DHTKD1	dehydrogenase E1 and transketolase domain containing 1	-2.96031
TBX2	T-box 2	-2.95947
TTF2	transcription termination factor, RNA polymerase II	-2.95938
UBE3C	ubiquitin protein ligase E3C	-2.9531
CRTAP	cartilage associated protein	-2.95262
FBXO7	F-box protein 7	-2.95135
ELP4	elongator acetyltransferase complex subunit 4	-2.95073
ASF1B	anti-silencing function 1B histone chaperone	-2.94699
GCSH	glycine cleavage system protein H (aminomethyl carrier)	-2.94523
FAHD2A	fumarylacetoacetate hydrolase domain containing 2A	-2.942
PIGN	phosphatidylinositol glycan anchor biosynthesis, class N	-2.94119
HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	-2.93735
LSM2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	-2.9371
USP1	ubiquitin specific peptidase 1	-2.93643
ATP5MC1	ATP synthase membrane subunit c locus 1	-2.93561
TMA16	translation machinery associated 16 homolog (S. cerevisiae)	-2.93482
YIF1A	Yip1 interacting factor homolog A (S. cerevisiae)	-2.93239
SEC16A	SEC16 homolog A (S. cerevisiae)	-2.93133
DMAC2L	distal membrane arm assembly component 2 like	-2.92954
PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3	-2.9289
RFC3	replication factor C (activator 1) 3, 38kDa	-2.92765
QDPR	quinoid dihydropteridine reductase	-2.92497
CCT6A	chaperonin containing TCP1, subunit 6A (zeta 1)	-2.92313
PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase, type I, beta	-2.92233
NSMCE4A	non-SMC element 4 homolog A (S. cerevisiae)	-2.92211
AKT1	v-akt murine thymoma viral oncogene homolog 1	-2.92013
WDR18	WD repeat domain 18	-2.91989
TRMT11	tRNA methyltransferase 11 homolog (S. cerevisiae)	-2.91783
PMS1	PMS1 postmeiotic segregation increased 1 (S. cerevisiae)	-2.91692
CDKN3	cyclin-dependent kinase inhibitor 3	-2.91634
SACM1L	SAC1 suppressor of actin mutations 1-like (yeast)	-2.91443
VPS26A	vacuolar protein sorting 26 homolog A (S. pombe)	-2.90858
AACS	acetoacetyl-CoA synthetase	-2.90434
MCUR1	mitochondrial calcium uniporter regulator 1	-2.89926
GALNT1	polypeptide N-acetylgalactosaminyltransferase 1	-2.89623
PPIP5K2	diphosphoinositol pentakisphosphate kinase 2	-2.89619
TPX2	TPX2, microtubule-associated	-2.89383
CHKA	choline kinase alpha	-2.89267
COL9A3	collagen, type IX, alpha 3	-2.89199
IGFBP1	insulin-like growth factor binding protein 1	-2.88982
CHAF1A	chromatin assembly factor 1, subunit A (p150)	-2.88878
NBAS	neuroblastoma amplified sequence	-2.87925
MRPL23	mitochondrial ribosomal protein L23	-2.87914
ALDH18A1	aldehyde dehydrogenase 18 family, member A1	-2.8788
PRC1	protein regulator of cytokinesis 1	-2.87341
DDX46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	-2.87137
UXT	ubiquitously-expressed, prefoldin-like chaperone	-2.86088
MNAT1	MNAT CDK-activating kinase assembly factor 1	-2.85709
DTYMK	deoxythymidylate kinase (thymidylate kinase)	-2.85007
OIP5	Opa interacting protein 5	-2.8496
EMC9	ER membrane protein complex subunit 9	-2.83756
SRSF3	serine/arginine-rich splicing factor 3	-2.83625
ITGB5	integrin, beta 5	-2.82841
SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)	-2.82721
SIPA1L1	signal-induced proliferation-associated 1 like 1	-2.82413
SCARB1	scavenger receptor class B, member 1	-2.82258
SKA1	spindle and kinetochore associated complex subunit 1	-2.81948
NPM3	nucleophosmin/nucleoplasmin 3	-2.81588
GALK1	galactokinase 1	-2.8134
GNE	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase	-2.8055
CHIC2	cysteine-rich hydrophobic domain 2	-2.80428
DSCC1	DNA replication and sister chromatid cohesion 1	-2.7977
EXO1	exonuclease 1	-2.79273
CADPS2	Ca++-dependent secretion activator 2	-2.78504
RACGAP1	Rac GTPase activating protein 1	-2.78358
MACF1	microtubule-actin crosslinking factor 1	-2.7829
PLEKHB1	pleckstrin homology domain containing, family B (evectins) member 1	-2.77463
PLK4	polo-like kinase 4	-2.77091
BORA	bora, aurora kinase A activator	-2.77045
GMPPA	GDP-mannose pyrophosphorylase A	-2.77002
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	-2.76964
SIGMAR1	sigma non-opioid intracellular receptor 1	-2.76315
ARL6IP4	ADP-ribosylation factor-like 6 interacting protein 4	-2.76224
GOLGA3	golgin A3	-2.76071
PLCXD1	phosphatidylinositol-specific phospholipase C, X domain containing 1	-2.75365
DDX54	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54	-2.74644
TTC27	tetratricopeptide repeat domain 27	-2.74558
ZMYM4	zinc finger, MYM-type 4	-2.74394
EVL	Enah/Vasp-like	-2.73188
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	-2.73153
MTCH2	mitochondrial carrier 2	-2.72766
MRS2	MRS2 magnesium transporter	-2.72501
ZBED1	zinc finger, BED-type containing 1	-2.72477
PHB1	prohibitin 1	-2.72334
COQ3	coenzyme Q3 methyltransferase	-2.72214
MRPS30	mitochondrial ribosomal protein S30	-2.722
CRCT1	cysteine-rich C-terminal 1	-2.71763
LARS2	leucyl-tRNA synthetase 2, mitochondrial	-2.7138
APOC3	apolipoprotein C-III	-2.71157
B4GALT6	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6	-2.70409
MRPL3	mitochondrial ribosomal protein L3	-2.70392
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	-2.70379
HMGB2	high mobility group box 2	-2.69658
SRBD1	S1 RNA binding domain 1	-2.69072
SELE	selectin E	-2.68895
NFIL3	nuclear factor, interleukin 3 regulated	-2.68887
YTHDF1	YTH N(6)-methyladenosine RNA binding protein 1	-2.68451
PGAP2	post-GPI attachment to proteins 2	-2.68027
PRMT3	protein arginine methyltransferase 3	-2.67707
RABGAP1L	RAB GTPase activating protein 1-like	-2.67557
BAHCC1	BAH domain and coiled-coil containing 1	-2.67483
PEPD	peptidase D	-2.67298
CPB2	carboxypeptidase B2 (plasma)	-2.67119
MAGED1	melanoma antigen family D1	-2.66378
TMEM123	transmembrane protein 123	-2.66242
NUP133	nucleoporin 133kDa	-2.65616
PUM2	pumilio RNA-binding family member 2	-2.6554
GNPDA1	glucosamine-6-phosphate deaminase 1	-2.6548
POLR3K	polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa	-2.65228
MBNL3	muscleblind-like splicing regulator 3	-2.65064
PUM3	pumilio RNA binding family member 3	-2.64904
CCS	copper chaperone for superoxide dismutase	-2.64883
CAPRIN1	cell cycle associated protein 1	-2.64852
KIF11	kinesin family member 11	-2.64851
ZNF106	zinc finger protein 106	-2.64494
CERK	ceramide kinase	-2.64132
AKR1D1	aldo-keto reductase family 1, member D1	-2.63834
ENO1	enolase 1, (alpha)	-2.63605
GNAS	GNAS complex locus	-2.63498
GAMT	guanidinoacetate N-methyltransferase	-2.63306
WDR12	WD repeat domain 12	-2.6254
RNF38	ring finger protein 38	-2.62507
INPP5A	inositol polyphosphate-5-phosphatase, 40kDa	-2.62165
ASNS	asparagine synthetase (glutamine-hydrolyzing)	-2.61917
CDCA3	cell division cycle associated 3	-2.61752
UQCR10	ubiquinol-cytochrome c reductase, complex III subunit X	-2.61713
TALDO1	transaldolase 1	-2.6158
ECHS1	enoyl CoA hydratase, short chain, 1, mitochondrial	-2.615
GUF1	GUF1 GTPase homolog (S. cerevisiae)	-2.61459
MYO10	myosin X	-2.613
POP5	processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)	-2.61121
GFPT1	glutamine--fructose-6-phosphate transaminase 1	-2.61058
STATH	statherin	-2.6045
GPC3	glypican 3	-2.60089
PCM1	pericentriolar material 1	-2.59963
UTP20	UTP20, small subunit (SSU) processome component, homolog (yeast)	-2.59534
LAS1L	LAS1-like (S. cerevisiae)	-2.58808
RTRAF	RNA transcription, translation and transport factor	-2.58366
FOCAD	focadhesin	-2.57767
GPHN	gephyrin	-2.57763
SRSF9	serine/arginine-rich splicing factor 9	-2.57544
OXA1L	oxidase (cytochrome c) assembly 1-like	-2.57535
ZWINT	ZW10 interacting kinetochore protein	-2.57169
HDAC2	histone deacetylase 2	-2.56396
FAAP100	FA core complex associated protein 100	-2.56347
SRP72	signal recognition particle 72kDa	-2.56031
ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	-2.55473
WASF3	WAS protein family, member 3	-2.5529
RAB15	RAB15, member RAS oncogene family	-2.55254
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	-2.55093
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	-2.54957
PRUNE1	prune exopolyphosphatase 1	-2.54937
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	-2.54915
GLB1L2	galactosidase, beta 1-like 2	-2.53383
GRSF1	G-rich RNA sequence binding factor 1	-2.53353
KIAA0586	KIAA0586	-2.53241
EIF4ENIF1	eukaryotic translation initiation factor 4E nuclear import factor 1	-2.53043
MRPL35	mitochondrial ribosomal protein L35	-2.52937
PTP4A2	protein tyrosine phosphatase type IVA, member 2	-2.52565
TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)	-2.52058
GTPBP6	GTP binding protein 6 (putative)	-2.52033
SEH1L	SEH1-like (S. cerevisiae)	-2.51955
EIF3B	eukaryotic translation initiation factor 3, subunit B	-2.51488
PUS1	pseudouridylate synthase 1	-2.51453
DHRS4	dehydrogenase/reductase (SDR family) member 4	-2.51197
PRH1	proline-rich protein HaeIII subfamily 1	-2.51125
KIF18B	kinesin family member 18B	-2.51119
GRHPR	glyoxylate reductase/hydroxypyruvate reductase	-2.50216
DFFB	DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)	-2.50193
FAM216A	family with sequence similarity 216, member A	-2.49821
MCRS1	microspherule protein 1	-2.49761
FEN1	flap structure-specific endonuclease 1	-2.4885
CKAP5	cytoskeleton associated protein 5	-2.4868
TK1	thymidine kinase 1, soluble	-2.48581
GDI2	GDP dissociation inhibitor 2	-2.48212
IARS2	isoleucyl-tRNA synthetase 2, mitochondrial	-2.48043
FBF1	Fas (TNFRSF6) binding factor 1	-2.47985
TUBG1	tubulin, gamma 1	-2.47872
DCPH1	damage control phosphatase 1	-2.47707
TBC1D16	TBC1 domain family, member 16	-2.47286
SORD	sorbitol dehydrogenase	-2.46715
SUZ12	SUZ12 polycomb repressive complex 2 subunit	-2.46193
LYPLA1-TCEA1	LYPLA1-TCEA1 readthrough	-2.46003
MPST	mercaptopyruvate sulfurtransferase	-2.46
SLIRP	SRA stem-loop interacting RNA binding protein	-2.45934
FBL	fibrillarin	-2.45789
HBQ1	hemoglobin, theta 1	-2.45376
CEP43	centrosomal protein 43	-2.45372
MAP3K1	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	-2.45252
NOLC1	nucleolar and coiled-body phosphoprotein 1	-2.45222
C1QBP	complement component 1, q subcomponent binding protein	-2.45087
BIRC2	baculoviral IAP repeat containing 2	-2.45082
PDCD5	programmed cell death 5	-2.45017
CERS1	ceramide synthase 1	-2.44938
CASP3	caspase 3, apoptosis-related cysteine peptidase	-2.44678
ANAPC5	anaphase promoting complex subunit 5	-2.44588
SLC6A14	solute carrier family 6 (amino acid transporter), member 14	-2.44302
NEK4	NIMA-related kinase 4	-2.43905
BUD23	BUD23 rRNA methyltransferase and ribosome maturation factor	-2.43871
S100B	S100 calcium binding protein B	-2.43817
GINS2	GINS complex subunit 2 (Psf2 homolog)	-2.43744
TMEM50A	transmembrane protein 50A	-2.4368
F7	coagulation factor VII (serum prothrombin conversion accelerator)	-2.43668
USO1	USO1 vesicle transport factor	-2.42574
SEC23IP	SEC23 interacting protein	-2.42542
VDAC1	voltage-dependent anion channel 1	-2.42413
RPA3	replication protein A3, 14kDa	-2.42389
PAH	phenylalanine hydroxylase	-2.42177
CDT1	chromatin licensing and DNA replication factor 1	-2.41701
PHF10	PHD finger protein 10	-2.4121
PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	-2.41173
SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	-2.40937
ADI1	acireductone dioxygenase 1	-2.40907
MYBPC1	myosin binding protein C, slow type	-2.409
NUDT1	nudix (nucleoside diphosphate linked moiety X)-type motif 1	-2.40731
RCC1L	RCC1 like	-2.40632
SLC19A2	solute carrier family 19 (thiamine transporter), member 2	-2.40533
ERP29	endoplasmic reticulum protein 29	-2.40369
FBXO11	F-box protein 11	-2.40202
ERH	enhancer of rudimentary homolog (Drosophila)	-2.39841
PPP4R1	protein phosphatase 4, regulatory subunit 1	-2.39731
SNX5	sorting nexin 5	-2.39546
LTBP1	latent transforming growth factor beta binding protein 1	-2.3951
CLN6	ceroid-lipofuscinosis, neuronal 6, late infantile, variant	-2.39333
FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)	-2.39297
AHSA1	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	-2.38853
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	-2.38647
CAMKK2	calcium/calmodulin-dependent protein kinase kinase 2, beta	-2.38454
RPL36AL	ribosomal protein L36a-like	-2.37872
NSF	N-ethylmaleimide-sensitive factor	-2.3769
DCAF17	DDB1 and CUL4 associated factor 17	-2.37614
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	-2.37553
CBX5	chromobox homolog 5	-2.37177
RTCB	RNA 2',3'-cyclic phosphate and 5'-OH ligase	-2.3703
COPB2	coatomer protein complex, subunit beta 2 (beta prime)	-2.36847
VCP	valosin containing protein	-2.36785
ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	-2.36702
ACOT2	acyl-CoA thioesterase 2	-2.35932
PTER	phosphotriesterase related	-2.35839
PPIH	peptidylprolyl isomerase H (cyclophilin H)	-2.35644
PARP2	poly (ADP-ribose) polymerase 2	-2.35412
RRAGA	Ras-related GTP binding A	-2.35371
MGA	MGA, MAX dimerization protein	-2.35271
FIRRM	FIGNL1 interacting regulator of recombination and mitosis	-2.3506
PANK3	pantothenate kinase 3	-2.35032
POLR2F	polymerase (RNA) II (DNA directed) polypeptide F	-2.34715
JPT1	Jupiter microtubule associated homolog 1	-2.34285
CPED1	cadherin-like and PC-esterase domain containing 1	-2.33996
LTF	lactotransferrin	-2.33827
GLYAT	glycine-N-acyltransferase	-2.33777
BCLAF1	BCL2-associated transcription factor 1	-2.33556
ATOX1	antioxidant 1 copper chaperone	-2.33454
CENPS-CORT	CENPS-CORT readthrough	-2.33216
HNRNPDL	heterogeneous nuclear ribonucleoprotein D-like	-2.32828
MLH3	mutL homolog 3	-2.32799
PIGH	phosphatidylinositol glycan anchor biosynthesis, class H	-2.32761
GSTM5	glutathione S-transferase mu 5	-2.32696
RAMP3	receptor (G protein-coupled) activity modifying protein 3	-2.32679
COPS7A	COP9 signalosome subunit 7A	-2.32635
DYNLL1	dynein, light chain, LC8-type 1	-2.32199
RGN	regucalcin	-2.31797
FAM193A	family with sequence similarity 193, member A	-2.31655
NAT10	N-acetyltransferase 10 (GCN5-related)	-2.31521
MRPL11	mitochondrial ribosomal protein L11	-2.31401
DNAJC9	DnaJ (Hsp40) homolog, subfamily C, member 9	-2.30924
ETV4	ets variant 4	-2.30704
IFT81	intraflagellar transport 81	-2.30537
FLT3	fms-related tyrosine kinase 3	-2.30258
GTF2H5	general transcription factor IIH, polypeptide 5	-2.30181
MTTP	microsomal triglyceride transfer protein	-2.30162
TEDC2	tubulin epsilon and delta complex 2	-2.30013
CX3CL1	chemokine (C-X3-C motif) ligand 1	-2.29996
CSTF3	cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa	-2.29919
ENTR1	endosome associated trafficking regulator 1	-2.29895
TIPIN	TIMELESS interacting protein	-2.29883
RTN3	reticulon 3	-2.29844
SERP1	stress-associated endoplasmic reticulum protein 1	-2.29797
PRPF38B	pre-mRNA processing factor 38B	-2.29772
GPD1L	glycerol-3-phosphate dehydrogenase 1-like	-2.2949
OAZ1	ornithine decarboxylase antizyme 1	-2.29393
SERBP1	SERPINE1 mRNA binding protein 1	-2.2937
MIS18BP1	MIS18 binding protein 1	-2.29309
MRPL42	mitochondrial ribosomal protein L42	-2.28701
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	-2.28441
PRSS58	protease, serine, 58	-2.27743
ACYP1	acylphosphatase 1, erythrocyte (common) type	-2.27656
HPD	4-hydroxyphenylpyruvate dioxygenase	-2.27274
CTBP1	C-terminal binding protein 1	-2.27023
AKAP11	A kinase (PRKA) anchor protein 11	-2.26773
CHD1L	chromodomain helicase DNA binding protein 1-like	-2.2676
SNUPN	snurportin 1	-2.26553
ACOX3	acyl-CoA oxidase 3, pristanoyl	-2.26472
PIERCE1	piercer of microtubule wall 1	-2.26418
NR2F1	nuclear receptor subfamily 2, group F, member 1	-2.26324
PRPSAP1	phosphoribosyl pyrophosphate synthetase-associated protein 1	-2.26026
PEF1	penta-EF-hand domain containing 1	-2.25595
CCT3	chaperonin containing TCP1, subunit 3 (gamma)	-2.25484
NSD2	nuclear receptor binding SET domain protein 2	-2.25459
MCM7	minichromosome maintenance complex component 7	-2.25189
HBG1	hemoglobin, gamma A	-2.25109
PKIG	protein kinase (cAMP-dependent, catalytic) inhibitor gamma	-2.2485
SOX10	SRY (sex determining region Y)-box 10	-2.24441
HMGB1	high mobility group box 1	-2.24415
NDUFB6	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa	-2.24356
ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like	-2.24195
PRODH	proline dehydrogenase (oxidase) 1	-2.24128
MRPS7	mitochondrial ribosomal protein S7	-2.24031
ARHGAP5	Rho GTPase activating protein 5	-2.23668
DNPH1	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	-2.23512
MPC1	mitochondrial pyruvate carrier 1	-2.23493
CAVIN2	caveolae associated protein 2	-2.23286
NUP37	nucleoporin 37kDa	-2.22692
KIF20B	kinesin family member 20B	-2.22458
GK	glycerol kinase	-2.21971
IPO5	importin 5	-2.21698
NDUFV1	NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa	-2.2167
RLIG1	RNA 5'-phosphate and 3'-OH ligase 1	-2.21661
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	-2.21575
PA2G4	proliferation-associated 2G4, 38kDa	-2.21545
RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3	-2.21413
DKC1	dyskeratosis congenita 1, dyskerin	-2.21326
USP39	ubiquitin specific peptidase 39	-2.21278
HSD17B11	hydroxysteroid (17-beta) dehydrogenase 11	-2.21107
RMI1	RecQ mediated genome instability 1	-2.20784
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	-2.20694
MDH2	malate dehydrogenase 2, NAD (mitochondrial)	-2.20473
DUSP9	dual specificity phosphatase 9	-2.19839
RHOT1	ras homolog family member T1	-2.19432
TOP2B	topoisomerase (DNA) II beta 180kDa	-2.19189
KDM3B	lysine (K)-specific demethylase 3B	-2.18711
NEK2	NIMA-related kinase 2	-2.18528
C1GALT1	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	-2.18423
DHRS1	dehydrogenase/reductase (SDR family) member 1	-2.18345
BCKDHB	branched chain keto acid dehydrogenase E1, beta polypeptide	-2.1833
GAR1	GAR1 ribonucleoprotein	-2.18306
FXN	frataxin	-2.18052
CBFB	core-binding factor, beta subunit	-2.17964
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	-2.17962
PRSS2	protease, serine, 2 (trypsin 2)	-2.17931
CHI3L2	chitinase 3-like 2	-2.1777
VWA8	von Willebrand factor A domain containing 8	-2.17755
SNF8	SNF8, ESCRT-II complex subunit	-2.17702
SLK	STE20-like kinase	-2.17608
SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	-2.17605
HDAC6	histone deacetylase 6	-2.1753
PDIA5	protein disulfide isomerase family A, member 5	-2.17241
A1CF	APOBEC1 complementation factor	-2.1701
VDAC3	voltage-dependent anion channel 3	-2.16659
PRPS2	phosphoribosyl pyrophosphate synthetase 2	-2.16597
KAZALD1	Kazal-type serine peptidase inhibitor domain 1	-2.16521
PDSS1	prenyl (decaprenyl) diphosphate synthase, subunit 1	-2.16421
LYL1	lymphoblastic leukemia associated hematopoiesis regulator 1	-2.16306
PRMT5	protein arginine methyltransferase 5	-2.16253
LMNB1	lamin B1	-2.16149
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	-2.15946
ARHGAP19	Rho GTPase activating protein 19	-2.15885
TMX1	thioredoxin-related transmembrane protein 1	-2.15807
GFUS	GDP-L-fucose synthase	-2.15723
NECTIN4	nectin cell adhesion molecule 4	-2.1559
SLC2A10	solute carrier family 2 (facilitated glucose transporter), member 10	-2.1528
LIPC	lipase, hepatic	-2.15278
DBF4	DBF4 zinc finger	-2.15051
PDE3B	phosphodiesterase 3B, cGMP-inhibited	-2.14951
NPAS2	neuronal PAS domain protein 2	-2.1479
CDK2AP1	cyclin-dependent kinase 2 associated protein 1	-2.14785
PSPH	phosphoserine phosphatase	-2.14614
HAUS7	HAUS augmin-like complex, subunit 7	-2.1455
GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide	-2.14535
GCN1	GCN1 activator of EIF2AK4	-2.14353
POLR1E	polymerase (RNA) I polypeptide E, 53kDa	-2.14295
NUS1	nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)	-2.1423
TXLNG	taxilin gamma	-2.14055
CENPM	centromere protein M	-2.13787
LMAN1	lectin, mannose-binding, 1	-2.13786
NLE1	notchless homolog 1 (Drosophila)	-2.13648
WASHC4	WASH complex subunit 4	-2.13645
FNBP1L	formin binding protein 1-like	-2.13408
SLC25A20	solute carrier family 25 (carnitine/acylcarnitine translocase), member 20	-2.13364
TDP1	tyrosyl-DNA phosphodiesterase 1	-2.13269
AQP5	aquaporin 5	-2.13241
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	-2.13113
ATAD2	ATPase family, AAA domain containing 2	-2.12956
BUB1	BUB1 mitotic checkpoint serine/threonine kinase	-2.1263
PIMREG	PICALM interacting mitotic regulator	-2.12502
NUP93	nucleoporin 93kDa	-2.12462
NOC3L	nucleolar complex associated 3 homolog (S. cerevisiae)	-2.12302
SRSF2	serine/arginine-rich splicing factor 2	-2.12217
NUP210	nucleoporin 210kDa	-2.1219
NEDD8	neural precursor cell expressed, developmentally down-regulated 8	-2.12179
QSER1	glutamine and serine rich 1	-2.12092
LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	-2.12043
LIME1	Lck interacting transmembrane adaptor 1	-2.11974
ATP6V0E2	ATPase, H+ transporting V0 subunit e2	-2.11906
ENOSF1	enolase superfamily member 1	-2.11899
CXCL8	chemokine (C-X-C motif) ligand 8	-2.11743
THG1L	tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)	-2.11722
PTBP1	polypyrimidine tract binding protein 1	-2.11647
ELF5	E74-like factor 5 (ets domain transcription factor)	-2.11536
VCAM1	vascular cell adhesion molecule 1	-2.11532
UGT2B28	UDP glucuronosyltransferase 2 family, polypeptide B28	-2.11477
PRDX1	peroxiredoxin 1	-2.11196
POLD2	polymerase (DNA directed), delta 2, accessory subunit	-2.11053
GPS1	G protein pathway suppressor 1	-2.11026
CNPY2	canopy FGF signaling regulator 2	-2.10838
PPARG	peroxisome proliferator-activated receptor gamma	-2.10678
HYOU1	hypoxia up-regulated 1	-2.10605
UXS1	UDP-glucuronate decarboxylase 1	-2.10369
EXOSC9	exosome component 9	-2.10343
HDAC3	histone deacetylase 3	-2.103
HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	-2.09923
HOOK1	hook microtubule-tethering protein 1	-2.09908
PDHA1	pyruvate dehydrogenase (lipoamide) alpha 1	-2.09859
KLK12	kallikrein-related peptidase 12	-2.09549
RSAD1	radical S-adenosyl methionine domain containing 1	-2.09321
SAE1	SUMO1 activating enzyme subunit 1	-2.09319
AURKB	aurora kinase B	-2.08541
SHCBP1	SHC SH2-domain binding protein 1	-2.0854
RNASE4	ribonuclease, RNase A family, 4	-2.08412
THAP7	THAP domain containing 7	-2.08372
NDUFS7	NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)	-2.08264
SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7	-2.08199
ATP5F1A	ATP synthase F1 subunit alpha	-2.08096
HEATR3	HEAT repeat containing 3	-2.07994
SSRP1	structure specific recognition protein 1	-2.07957
SLC2A4RG	SLC2A4 regulator	-2.07913
MED28	mediator complex subunit 28	-2.07047
NIT2	nitrilase family, member 2	-2.06753
IGLL1	immunoglobulin lambda-like polypeptide 1	-2.06573
PHB2	prohibitin 2	-2.06515
HADH	hydroxyacyl-CoA dehydrogenase	-2.06217
UNG	uracil-DNA glycosylase	-2.0613
KIF18A	kinesin family member 18A	-2.06049
PUS7	pseudouridylate synthase 7 (putative)	-2.05994
APEH	acylaminoacyl-peptide hydrolase	-2.05804
NARS1	asparaginyl-tRNA synthetase 1	-2.05578
ANG	angiogenin, ribonuclease, RNase A family, 5	-2.05218
CASP7	caspase 7, apoptosis-related cysteine peptidase	-2.0517
FIBP	fibroblast growth factor (acidic) intracellular binding protein	-2.04777
SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)	-2.0476
RIOX2	ribosomal oxygenase 2	-2.04654
MDN1	MDN1, midasin homolog (yeast)	-2.04601
ACADSB	acyl-CoA dehydrogenase, short/branched chain	-2.04495
GTF2I	general transcription factor IIi	-2.0416
TMED3	transmembrane emp24 protein transport domain containing 3	-2.04149
PTPN11	protein tyrosine phosphatase, non-receptor type 11	-2.03797
MRPS17	mitochondrial ribosomal protein S17	-2.03616
DICER1	dicer 1, ribonuclease type III	-2.03321
P2RX5	purinergic receptor P2X, ligand gated ion channel, 5	-2.03294
IARS1	isoleucyl-tRNA synthetase 1	-2.02735
HSPA14	heat shock 70kDa protein 14	-2.02712
SERPINA2	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene)	-2.02632
TSLIG3A	tRNA splicing ligase complex subunit 3A	-2.02464
SEPTIN8	septin 8	-2.02341
GOLPH3	golgi phosphoprotein 3 (coat-protein)	-2.02329
SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)	-2.02316
EEIG1	estrogen-induced osteoclastogenesis regulator 1	-2.02262
HARS1	histidyl-tRNA synthetase 1	-2.02042
CTDNEP1	CTD nuclear envelope phosphatase 1	-2.014
ITIH3	inter-alpha-trypsin inhibitor heavy chain 3	-2.01312
HGD	homogentisate 1,2-dioxygenase	-2.0129
CRLF3	cytokine receptor-like factor 3	-2.01217
KAT5	K(lysine) acetyltransferase 5	-2.00741
ADD1	adducin 1 (alpha)	-2.00734
APOA1	apolipoprotein A-I	-2.00705
PTCD3	pentatricopeptide repeat domain 3	-2.00693
TIMM23	translocase of inner mitochondrial membrane 23 homolog (yeast)	-2.00571
WDR77	WD repeat domain 77	-2.0006

Harmonizome 3.0

CRCGN010_HEPG2_24H:C22 Gene Set

Genes

increased expression

decreased expression

Please acknowledge the Harmonizome in your publications by citing the following reference(s):