CRCGN010_HEPG2_24H:D03 Gene Set
Genes
36 genes differentially expressed following the CRCGN010_HEPG2_24H:D03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
5.50751
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.09146
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
4.54942
|
|
JADE2
|
jade family PHD finger 2
|
4.14376
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.82301
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
3.46926
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.2405
|
|
LCN2
|
lipocalin 2
|
3.23666
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.23637
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.00938
|
|
MYLK
|
myosin light chain kinase
|
2.94196
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.85336
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.8245
|
|
GPATCH8
|
G patch domain containing 8
|
2.70662
|
|
NENF
|
neudesin neurotrophic factor
|
2.61007
|
|
CTSL
|
cathepsin L
|
2.46128
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.43752
|
|
SH3BP4
|
SH3-domain binding protein 4
|
2.11463
|
|
BARD1
|
BRCA1 associated RING domain 1
|
2.11326
|
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
2.03191
|
|
NRTN
|
neurturin
|
2.02886
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
CCNB2
|
cyclin B2
|
-10.0
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-7.97164
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-4.82121
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-4.1831
|
|
ZNF586
|
zinc finger protein 586
|
-3.57768
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.27954
|
|
RNF167
|
ring finger protein 167
|
-3.12524
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-2.70239
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.67582
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.67229
|
|
TLR4
|
toll-like receptor 4
|
-2.41871
|
|
OSTF1
|
osteoclast stimulating factor 1
|
-2.10426
|
|
CD58
|
CD58 molecule
|
-2.05207
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.00277
|
