CRCGN010_HEPG2_24H:D04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hexylresorcinol 5.02 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

38 genes differentially expressed following the CRCGN010_HEPG2_24H:D04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ATP11B ATPase, class VI, type 11B 8.65588
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 5.52221
STIMATE STIM activating enhancer 4.8283
E2F2 E2F transcription factor 2 4.75052
PPARG peroxisome proliferator-activated receptor gamma 4.3963
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 4.33689
CARMIL1 capping protein regulator and myosin 1 linker 1 4.07682
NMU neuromedin U 3.68134
ABHD6 abhydrolase domain containing 6 3.58115
TBC1D10C TBC1 domain family, member 10C 3.53608
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.21767
MINDY1 MINDY lysine 48 deubiquitinase 1 2.97162
NOSIP nitric oxide synthase interacting protein 2.42484
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 2.34289
STK10 serine/threonine kinase 10 2.32629
PKN1 protein kinase N1 2.28147
CYCS cytochrome c, somatic 2.24842
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.24306
CRTAP cartilage associated protein 2.16467
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.13603
LPAR2 lysophosphatidic acid receptor 2 2.11414
HLA-DRA major histocompatibility complex, class II, DR alpha 2.05676
AMDHD2 amidohydrolase domain containing 2 2.05615
CBR3 carbonyl reductase 3 2.04796

decreased expression

Symbol Name Standardized Value
VAT1 vesicle amine transport 1 -4.53549
ZNF586 zinc finger protein 586 -4.25882
UGDH UDP-glucose 6-dehydrogenase -4.24047
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.91718
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.74314
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.73481
PCNA proliferating cell nuclear antigen -3.60662
TLCD3A TLC domain containing 3A -2.6978
OXA1L oxidase (cytochrome c) assembly 1-like -2.67262
TOR1A torsin family 1, member A (torsin A) -2.3918
GNAS GNAS complex locus -2.13123
NRIP1 nuclear receptor interacting protein 1 -2.11634
TM9SF3 transmembrane 9 superfamily member 3 -2.11112
NGRN neugrin, neurite outgrowth associated -2.03843