| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hexylresorcinol 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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96 genes differentially expressed following the CRCGN010_HEPG2_24H:D06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 7.50828 |
| ATP11B | ATPase, class VI, type 11B | 6.47413 |
| PMM2 | phosphomannomutase 2 | 6.1491 |
| ZFP36 | ZFP36 ring finger protein | 5.79325 |
| NOTCH1 | notch 1 | 5.36643 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.15528 |
| NMU | neuromedin U | 4.59537 |
| STK10 | serine/threonine kinase 10 | 4.29342 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 4.25859 |
| MAMLD1 | mastermind-like domain containing 1 | 4.25727 |
| CHMP6 | charged multivesicular body protein 6 | 4.20771 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.10968 |
| MAP7 | microtubule-associated protein 7 | 3.99871 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.96979 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.90355 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.82565 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 3.73973 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.65435 |
| TENT4A | terminal nucleotidyltransferase 4A | 3.59964 |
| MYLK | myosin light chain kinase | 3.46463 |
| SFTPB | surfactant protein B | 3.32797 |
| MCM3 | minichromosome maintenance complex component 3 | 3.29978 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.26692 |
| TESK1 | testis-specific kinase 1 | 2.9933 |
| PFKL | phosphofructokinase, liver | 2.78158 |
| RGS9BP | regulator of G protein signaling 9 binding protein | 2.68116 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 | 2.67678 |
| CHN1 | chimerin 1 | 2.65545 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 2.58809 |
| LOC122526780 | uncharacterized LOC122526780 | 2.561 |
| ZNF589 | zinc finger protein 589 | 2.54754 |
| APP | amyloid beta (A4) precursor protein | 2.52435 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.51831 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.4875 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.48019 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.40622 |
| PRR15L | proline rich 15-like | 2.30447 |
| BRD9 | bromodomain containing 9 | 2.25861 |
| TXNDC5 | thioredoxin domain containing 5 (endoplasmic reticulum) | 2.23774 |
| EDN1 | endothelin 1 | 2.23332 |
| TDO2 | tryptophan 2,3-dioxygenase | 2.2301 |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 2.13606 |
| SATB1 | SATB homeobox 1 | 2.13127 |
| GATA2 | GATA binding protein 2 | 2.12653 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.12029 |
| ADGRB2 | adhesion G protein-coupled receptor B2 | 2.09476 |
| TENM3 | teneurin transmembrane protein 3 | 2.0578 |
| YEATS2 | YEATS domain containing 2 | 2.04995 |
| EED | embryonic ectoderm development | 2.04586 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) | 2.00854 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -9.09789 |
| ZNF586 | zinc finger protein 586 | -8.01843 |
| CCNB2 | cyclin B2 | -5.30357 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -5.19302 |
| GTPBP8 | GTP-binding protein 8 (putative) | -4.92785 |
| PLK1 | polo-like kinase 1 | -4.91585 |
| LDHD | lactate dehydrogenase D | -4.90103 |
| SCAND1 | SCAN domain containing 1 | -4.78413 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -4.66227 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.60599 |
| TRIB3 | tribbles pseudokinase 3 | -4.51259 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.48093 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.46593 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -4.43677 |
| DERA | deoxyribose-phosphate aldolase (putative) | -4.41742 |
| RNF167 | ring finger protein 167 | -4.16265 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.14263 |
| GNAS | GNAS complex locus | -4.00039 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.94432 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.71032 |
| LYPLA1 | lysophospholipase I | -3.5855 |
| HEATR1 | HEAT repeat containing 1 | -3.30528 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.10512 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -3.09056 |
| PDZD2 | PDZ domain containing 2 | -2.97507 |
| ZW10 | zw10 kinetochore protein | -2.93157 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.83346 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.82372 |
| TLR4 | toll-like receptor 4 | -2.80226 |
| YME1L1 | YME1-like 1 ATPase | -2.65018 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.61858 |
| SCCPDH | saccharopine dehydrogenase (putative) | -2.5802 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.45268 |
| LGMN | legumain | -2.44849 |
| DARS2 | aspartyl-tRNA synthetase 2, mitochondrial | -2.31933 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 | -2.31851 |
| INTS9 | integrator complex subunit 9 | -2.29959 |
| PPOX | protoporphyrinogen oxidase | -2.19835 |
| UNC13D | unc-13 homolog D (C. elegans) | -2.19781 |
| RNF24 | ring finger protein 24 | -2.14844 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.08147 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -2.07176 |
| TCTN1 | tectonic family member 1 | -2.06484 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.064 |
| CDK5 | cyclin-dependent kinase 5 | -2.05105 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -2.00473 |
