CRCGN010_HEPG2_24H:D07 Gene Set
Genes
56 genes differentially expressed following the CRCGN010_HEPG2_24H:D07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PMM2
|
phosphomannomutase 2
|
5.06329
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.47927
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.38873
|
|
MYLK
|
myosin light chain kinase
|
4.36147
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.98612
|
|
PHKG2
|
phosphorylase kinase, gamma 2 (testis)
|
3.93996
|
|
IDE
|
insulin-degrading enzyme
|
3.53807
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.38051
|
|
EVL
|
Enah/Vasp-like
|
3.18853
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.07403
|
|
GPATCH8
|
G patch domain containing 8
|
2.98037
|
|
MAP7
|
microtubule-associated protein 7
|
2.94972
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.91114
|
|
GATA3
|
GATA binding protein 3
|
2.73195
|
|
CBR3
|
carbonyl reductase 3
|
2.6233
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.6084
|
|
SYK
|
spleen tyrosine kinase
|
2.56146
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.53209
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.47202
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.41824
|
|
SFTPB
|
surfactant protein B
|
2.41444
|
|
CREG1
|
cellular repressor of E1A-stimulated genes 1
|
2.3584
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.27392
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.22636
|
|
PLEKHA1
|
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
|
2.08154
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.0157
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
THAP11
|
THAP domain containing 11
|
-4.76302
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-4.70443
|
|
CD320
|
CD320 molecule
|
-4.60428
|
|
DNM1L
|
dynamin 1-like
|
-4.41025
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-4.37363
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.23192
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.08104
|
|
GOLT1B
|
golgi transport 1B
|
-4.07771
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.03038
|
|
ZNF586
|
zinc finger protein 586
|
-3.95533
|
|
LDHD
|
lactate dehydrogenase D
|
-3.94797
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.84338
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.83871
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.83452
|
|
SCAND1
|
SCAN domain containing 1
|
-3.37389
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.28823
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.25813
|
|
GNAS
|
GNAS complex locus
|
-3.20573
|
|
RNF167
|
ring finger protein 167
|
-3.20392
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.14708
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.11086
|
|
SCCPDH
|
saccharopine dehydrogenase (putative)
|
-2.90328
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.77158
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.65897
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
-2.41459
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.39417
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.32044
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
-2.19223
|
|
C5
|
complement component 5
|
-2.11257
|
|
STMN1
|
stathmin 1
|
-2.00402
|
