| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-nitrosodiethanolamine 19.7 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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87 genes differentially expressed following the CRCGN010_HEPG2_24H:D08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 6.79586 |
| ABHD6 | abhydrolase domain containing 6 | 5.8766 |
| MAP7 | microtubule-associated protein 7 | 5.17081 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 4.37193 |
| ATP11B | ATPase, class VI, type 11B | 3.92933 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.85509 |
| GATA3 | GATA binding protein 3 | 3.83133 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.83021 |
| PNKP | polynucleotide kinase 3'-phosphatase | 3.80588 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 3.77809 |
| PRR15L | proline rich 15-like | 3.77298 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.64364 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 3.63984 |
| UBQLN2 | ubiquilin 2 | 3.62646 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.60107 |
| NOTCH1 | notch 1 | 3.57671 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.52232 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.43322 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.27033 |
| NMU | neuromedin U | 3.22499 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 3.19854 |
| MOK | MOK protein kinase | 3.17351 |
| DIPK1A | divergent protein kinase domain 1A | 2.99232 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.98137 |
| JADE2 | jade family PHD finger 2 | 2.88009 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 2.79087 |
| STIMATE | STIM activating enhancer | 2.68728 |
| CSK | c-src tyrosine kinase | 2.62646 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.59594 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 2.59523 |
| SMIM40 | small integral membrane protein 40 | 2.55337 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.52572 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.4989 |
| CHMP6 | charged multivesicular body protein 6 | 2.43084 |
| SFTPB | surfactant protein B | 2.3595 |
| HSPA8 | heat shock 70kDa protein 8 | 2.33313 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 2.21373 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.20605 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 2.14373 |
| GLIPR1 | GLI pathogenesis-related 1 | 2.08505 |
| GPATCH8 | G patch domain containing 8 | 2.08442 |
| CEP57 | centrosomal protein 57kDa | 2.04559 |
| TBXA2R | thromboxane A2 receptor | 2.02402 |
| ALCAM | activated leukocyte cell adhesion molecule | 2.02375 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.01307 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 2.00088 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -9.18906 |
| PCNA | proliferating cell nuclear antigen | -6.54958 |
| VAT1 | vesicle amine transport 1 | -6.49307 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.12641 |
| LDHD | lactate dehydrogenase D | -6.09916 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.40347 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -3.91307 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.88067 |
| SNX11 | sorting nexin 11 | -3.53771 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.497 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.44186 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.39504 |
| CCNB1 | cyclin B1 | -3.35359 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.24598 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -3.2401 |
| ZNF586 | zinc finger protein 586 | -3.18898 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -3.18684 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.17735 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.12779 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.06969 |
| ZW10 | zw10 kinetochore protein | -2.97266 |
| XPO7 | exportin 7 | -2.97211 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.88792 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.63204 |
| FHL2 | four and a half LIM domains 2 | -2.53837 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.475 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.47102 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -2.44836 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.38232 |
| PRPF4 | pre-mRNA processing factor 4 | -2.28884 |
| ANAPC15 | anaphase promoting complex subunit 15 | -2.22805 |
| CD58 | CD58 molecule | -2.17453 |
| HMG20B | high mobility group 20B | -2.16572 |
| RNPEP | arginyl aminopeptidase (aminopeptidase B) | -2.11968 |
| FECH | ferrochelatase | -2.11902 |
| CPOX | coproporphyrinogen oxidase | -2.08818 |
| CCND3 | cyclin D3 | -2.06089 |
| KEL | Kell blood group, metallo-endopeptidase | -2.04565 |
| RETN | resistin | -2.0355 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -2.02193 |
| IVNS1ABP | influenza virus NS1A binding protein | -2.01364 |
