CRCGN010_HEPG2_24H:D13 Gene Set
Genes
43 genes differentially expressed following the CRCGN010_HEPG2_24H:D13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
10.0
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.7176
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
4.81184
|
|
SQOR
|
sulfide quinone oxidoreductase
|
4.44501
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.30428
|
|
CYCS
|
cytochrome c, somatic
|
4.24922
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
4.17736
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.10339
|
|
CSK
|
c-src tyrosine kinase
|
3.97177
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.95038
|
|
E2F2
|
E2F transcription factor 2
|
3.86731
|
|
UBQLN2
|
ubiquilin 2
|
3.83554
|
|
STK10
|
serine/threonine kinase 10
|
3.54488
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.24924
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.03644
|
|
MAP7
|
microtubule-associated protein 7
|
3.01194
|
|
HEBP1
|
heme binding protein 1
|
2.75888
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.70733
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.53168
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.4824
|
|
RBKS
|
ribokinase
|
2.21791
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.16252
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.11462
|
|
SMAD3
|
SMAD family member 3
|
2.07267
|
|
VGLL4
|
vestigial-like family member 4
|
2.05311
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-6.8055
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.33074
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.79789
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.72788
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.52928
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.57481
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.57347
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.56864
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.50839
|
|
TLR4
|
toll-like receptor 4
|
-3.17962
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.17329
|
|
DNM1L
|
dynamin 1-like
|
-2.91782
|
|
ATP6V0B
|
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
|
-2.85028
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.74896
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.74254
|
|
RAI14
|
retinoic acid induced 14
|
-2.35093
|
|
ALOX15B
|
arachidonate 15-lipoxygenase, type B
|
-2.32402
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.25855
|
