CRCGN010_HEPG2_24H:D16 Gene Set
Genes
42 genes differentially expressed following the CRCGN010_HEPG2_24H:D16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
8.45122
|
|
MAP7
|
microtubule-associated protein 7
|
7.81919
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.8196
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.83631
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.59712
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.95995
|
|
IDE
|
insulin-degrading enzyme
|
3.88834
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
3.78997
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.37126
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.14356
|
|
TXNL4B
|
thioredoxin-like 4B
|
3.0885
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
2.98309
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.50166
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.48758
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.47548
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
2.46966
|
|
CRBN
|
cereblon
|
2.39456
|
|
TPD52-MRPS28
|
TPD52-MRPS28 readthrough
|
2.25152
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.23719
|
|
HPRT1
|
hypoxanthine phosphoribosyltransferase 1
|
2.14812
|
|
MCTS1
|
malignant T cell amplified sequence 1
|
2.05412
|
|
REPS2
|
RALBP1 associated Eps domain containing 2
|
2.05035
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.02632
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-10.0
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-6.46307
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.39834
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-4.21033
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.83772
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.6998
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-3.6549
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.57908
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
-2.92417
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
-2.77635
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.73864
|
|
ETFB
|
electron-transfer-flavoprotein, beta polypeptide
|
-2.38017
|
|
CDK6
|
cyclin-dependent kinase 6
|
-2.19369
|
|
RNPEP
|
arginyl aminopeptidase (aminopeptidase B)
|
-2.1095
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-2.06294
|
|
RBM15
|
RNA binding motif protein 15
|
-2.05166
|
|
CDC37
|
cell division cycle 37
|
-2.04896
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
-2.03912
|
|
TBKBP1
|
TBK1 binding protein 1
|
-2.00752
|
