CRCGN010_HEPG2_24H:D17 Gene Set
Genes
47 genes differentially expressed following the CRCGN010_HEPG2_24H:D17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PRR15L
|
proline rich 15-like
|
4.58266
|
|
EVL
|
Enah/Vasp-like
|
4.37007
|
|
MYLK
|
myosin light chain kinase
|
3.62694
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.54036
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.42294
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.38355
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.32108
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.18933
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
3.05643
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.03282
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.00396
|
|
STK10
|
serine/threonine kinase 10
|
3.00089
|
|
WDR7
|
WD repeat domain 7
|
2.99024
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.97802
|
|
MAP7
|
microtubule-associated protein 7
|
2.86544
|
|
ADGRG1
|
adhesion G protein-coupled receptor G1
|
2.77432
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.56181
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.48537
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.48329
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.4557
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.33396
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.31179
|
|
GATA3
|
GATA binding protein 3
|
2.1968
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.04636
|
|
CHN1
|
chimerin 1
|
2.03465
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.02177
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CD320
|
CD320 molecule
|
-6.74471
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-6.49155
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.46833
|
|
ZNF586
|
zinc finger protein 586
|
-5.51262
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.7988
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-4.20475
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.67402
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.64672
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.40437
|
|
CDC20
|
cell division cycle 20
|
-3.37715
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.30287
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.27949
|
|
TLR4
|
toll-like receptor 4
|
-3.18949
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.14395
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.09655
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.95178
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.75121
|
|
CCNB2
|
cyclin B2
|
-2.71633
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.36995
|
|
TP53BP2
|
tumor protein p53 binding protein 2
|
-2.07838
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.03414
|
