| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dioxane 1.27 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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54 genes differentially expressed following the CRCGN010_HEPG2_24H:D18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 6.79629 |
| AMDHD2 | amidohydrolase domain containing 2 | 6.57644 |
| CHN1 | chimerin 1 | 5.39413 |
| ADRB2 | adrenoceptor beta 2, surface | 5.1536 |
| STK10 | serine/threonine kinase 10 | 4.86222 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.72804 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.38106 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.29856 |
| DENND2D | DENN/MADD domain containing 2D | 3.97135 |
| GPATCH8 | G patch domain containing 8 | 3.8636 |
| DIPK1A | divergent protein kinase domain 1A | 3.71953 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.60431 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.29958 |
| POLR2K | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | 3.27749 |
| MAMLD1 | mastermind-like domain containing 1 | 3.03016 |
| UBQLN2 | ubiquilin 2 | 2.99927 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.98089 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.9098 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.90979 |
| CCNA1 | cyclin A1 | 2.80519 |
| SMAD3 | SMAD family member 3 | 2.78365 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 2.61141 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.40608 |
| SHB | Src homology 2 domain containing adaptor protein B | 2.31842 |
| ALDOC | aldolase C, fructose-bisphosphate | 2.26065 |
| MMD | monocyte to macrophage differentiation-associated | 2.12315 |
| ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 | 2.08816 |
| EVI2A | ecotropic viral integration site 2A | 2.03126 |
| LASP1 | LIM and SH3 protein 1 | 2.02926 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -6.24664 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.64708 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.40637 |
| ADI1 | acireductone dioxygenase 1 | -3.79707 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.65837 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.63551 |
| WASHC4 | WASH complex subunit 4 | -3.4879 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.34678 |
| RNF167 | ring finger protein 167 | -3.22412 |
| HMG20B | high mobility group 20B | -3.19998 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -3.0754 |
| PCNA | proliferating cell nuclear antigen | -3.07533 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.89769 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.68747 |
| NVL | nuclear VCP-like | -2.50576 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -2.4228 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.31609 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.23707 |
| ZNF133 | zinc finger protein 133 | -2.2116 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.20348 |
| RNF130 | ring finger protein 130 | -2.10361 |
| BANP | BTG3 associated nuclear protein | -2.10359 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.06391 |
| NUP58 | nucleoporin 58 | -2.04096 |
| XPC | xeroderma pigmentosum, complementation group C | -2.01418 |
