| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tris(1,3-dichloro-2-propyl) phosphate 39.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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92 genes differentially expressed following the CRCGN010_HEPG2_24H:D19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AMDHD2 | amidohydrolase domain containing 2 | 4.91664 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.65308 |
| DDIT4 | DNA-damage-inducible transcript 4 | 4.44135 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.43469 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.97227 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 3.68488 |
| PNKP | polynucleotide kinase 3'-phosphatase | 3.52905 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.50908 |
| GATA3 | GATA binding protein 3 | 3.37865 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.24373 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 3.24321 |
| AARS1 | alanyl-tRNA synthetase 1 | 3.20925 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 3.18746 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 3.03468 |
| AXIN1 | axin 1 | 2.9738 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.92871 |
| CHEK2 | checkpoint kinase 2 | 2.85513 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.8376 |
| INPP1 | inositol polyphosphate-1-phosphatase | 2.79421 |
| RAP1GAP | RAP1 GTPase activating protein | 2.79193 |
| SQSTM1 | sequestosome 1 | 2.76938 |
| NUCB2 | nucleobindin 2 | 2.73287 |
| VAT1 | vesicle amine transport 1 | 2.71911 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.63509 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.62782 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 | 2.61655 |
| ZFP36 | ZFP36 ring finger protein | 2.61064 |
| LCN2 | lipocalin 2 | 2.5694 |
| STAP2 | signal transducing adaptor family member 2 | 2.51592 |
| HMOX1 | heme oxygenase 1 | 2.50593 |
| E2F2 | E2F transcription factor 2 | 2.48545 |
| BZW2 | basic leucine zipper and W2 domains 2 | 2.465 |
| CHMP6 | charged multivesicular body protein 6 | 2.42256 |
| NOSIP | nitric oxide synthase interacting protein | 2.40074 |
| EPHB2 | EPH receptor B2 | 2.37875 |
| PHGDH | phosphoglycerate dehydrogenase | 2.33842 |
| STIMATE | STIM activating enhancer | 2.33417 |
| TEX10 | testis expressed 10 | 2.2907 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 2.2778 |
| PMM2 | phosphomannomutase 2 | 2.25135 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 2.1897 |
| PRR15L | proline rich 15-like | 2.17915 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 | 2.13933 |
| MVP | major vault protein | 2.13512 |
| CYCS | cytochrome c, somatic | 2.12717 |
| CDK18 | cyclin-dependent kinase 18 | 2.039 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | 2.036 |
| GALE | UDP-galactose-4-epimerase | 2.00416 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TLR4 | toll-like receptor 4 | -5.84672 |
| FASTKD5 | FAST kinase domains 5 | -4.9443 |
| CDC20 | cell division cycle 20 | -4.43689 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -3.8941 |
| ZNF586 | zinc finger protein 586 | -3.75254 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.71822 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.59724 |
| LAP3 | leucine aminopeptidase 3 | -3.5793 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -3.56302 |
| ZNF274 | zinc finger protein 274 | -3.54923 |
| CD320 | CD320 molecule | -3.49442 |
| MELK | maternal embryonic leucine zipper kinase | -3.36071 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -3.27655 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.18109 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.13347 |
| THAP11 | THAP domain containing 11 | -3.10971 |
| CDK1 | cyclin-dependent kinase 1 | -2.96336 |
| EDN1 | endothelin 1 | -2.92582 |
| KIF14 | kinesin family member 14 | -2.89513 |
| MYL9 | myosin, light chain 9, regulatory | -2.79535 |
| HAT1 | histone acetyltransferase 1 | -2.70194 |
| SLC35F2 | solute carrier family 35, member F2 | -2.65743 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.6334 |
| PGAM4 | phosphoglycerate mutase family member 4 | -2.62672 |
| CCNA2 | cyclin A2 | -2.60566 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -2.58774 |
| TCTN1 | tectonic family member 1 | -2.35397 |
| TBPL1 | TBP-like 1 | -2.31784 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.30872 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -2.25657 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.23267 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -2.22058 |
| RPIA | ribose 5-phosphate isomerase A | -2.21775 |
| ADI1 | acireductone dioxygenase 1 | -2.20886 |
| USB1 | U6 snRNA biogenesis 1 | -2.16052 |
| BIRC5 | baculoviral IAP repeat containing 5 | -2.15739 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.14551 |
| SESN1 | sestrin 1 | -2.13931 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.12058 |
| MSN | moesin | -2.08725 |
| SMC4 | structural maintenance of chromosomes 4 | -2.06984 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -2.06438 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -2.00735 |
| ZW10 | zw10 kinetochore protein | -2.00653 |
