CRCGN010_HEPG2_24H:D20 Gene Set
Genes
60 genes differentially expressed following the CRCGN010_HEPG2_24H:D20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
6.13002
|
|
MOK
|
MOK protein kinase
|
6.10637
|
|
ATP11B
|
ATPase, class VI, type 11B
|
5.94423
|
|
MAP7
|
microtubule-associated protein 7
|
5.14706
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.2335
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.12811
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.7579
|
|
NMU
|
neuromedin U
|
3.6764
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
3.60657
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.47527
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.36726
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.31889
|
|
EPHB2
|
EPH receptor B2
|
3.27942
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.14774
|
|
INTS3
|
integrator complex subunit 3
|
3.13698
|
|
VGLL4
|
vestigial-like family member 4
|
2.97205
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.93552
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.90323
|
|
LCN2
|
lipocalin 2
|
2.8372
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.73496
|
|
MYLK
|
myosin light chain kinase
|
2.65764
|
|
CSK
|
c-src tyrosine kinase
|
2.53894
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.40657
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.30766
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.23522
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
2.07655
|
|
CLDN16
|
claudin 16
|
2.03477
|
|
APOH
|
apolipoprotein H (beta-2-glycoprotein I)
|
2.03168
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.08987
|
|
CCNB2
|
cyclin B2
|
-7.05917
|
|
TLR4
|
toll-like receptor 4
|
-5.08117
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.946
|
|
RPIA
|
ribose 5-phosphate isomerase A
|
-4.10383
|
|
DNM1L
|
dynamin 1-like
|
-4.07765
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.64527
|
|
ZW10
|
zw10 kinetochore protein
|
-3.62258
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.51291
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.29426
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.24398
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.18613
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.09824
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-2.91727
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.84927
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.83158
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.80866
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.78796
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.70518
|
|
ZNF586
|
zinc finger protein 586
|
-2.6178
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.52951
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.52589
|
|
WASHC4
|
WASH complex subunit 4
|
-2.43719
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.3658
|
|
VAT1
|
vesicle amine transport 1
|
-2.36497
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.29131
|
|
ZNHIT6
|
zinc finger, HIT-type containing 6
|
-2.17132
|
|
NAT10
|
N-acetyltransferase 10 (GCN5-related)
|
-2.14684
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.12581
|
|
SNX11
|
sorting nexin 11
|
-2.11892
|
|
BNIP2
|
BCL2/adenovirus E1B 19kDa interacting protein 2
|
-2.11215
|
|
CPM
|
carboxypeptidase M
|
-2.03823
|
