| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tris(1,3-dichloro-2-propyl) phosphate 9.95 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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65 genes differentially expressed following the CRCGN010_HEPG2_24H:D21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 6.0787 |
| ATP11B | ATPase, class VI, type 11B | 5.50474 |
| LOC122526780 | uncharacterized LOC122526780 | 5.33293 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.60529 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.60285 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.46349 |
| SQOR | sulfide quinone oxidoreductase | 4.1518 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.12122 |
| MAP7 | microtubule-associated protein 7 | 3.67827 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.47908 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.40489 |
| TESK1 | testis-specific kinase 1 | 3.15953 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.97877 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.88795 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 2.83911 |
| CCDC85B | coiled-coil domain containing 85B | 2.75165 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.73837 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.62156 |
| DPP3 | dipeptidyl-peptidase 3 | 2.51835 |
| GARS1 | glycyl-tRNA synthetase 1 | 2.41561 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.35258 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 2.32235 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 2.28337 |
| RAB5B | RAB5B, member RAS oncogene family | 2.18221 |
| BORA | bora, aurora kinase A activator | 2.1262 |
| STK25 | serine/threonine kinase 25 | 2.10995 |
| TOB1 | transducer of ERBB2, 1 | 2.08148 |
| STIMATE | STIM activating enhancer | 2.04314 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 2.04194 |
| ECD | ecdysoneless homolog (Drosophila) | 2.00745 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -8.65059 |
| TLR4 | toll-like receptor 4 | -7.7432 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.94971 |
| DERA | deoxyribose-phosphate aldolase (putative) | -5.61516 |
| NISCH | nischarin | -4.53032 |
| FAIM | Fas apoptotic inhibitory molecule | -4.25006 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.24047 |
| PCNA | proliferating cell nuclear antigen | -4.06813 |
| CDC20 | cell division cycle 20 | -3.94107 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.93991 |
| DSG2 | desmoglein 2 | -3.91779 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.84276 |
| WASHC4 | WASH complex subunit 4 | -3.82569 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.72412 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.67539 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -3.52409 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -3.37526 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -3.06088 |
| RBM15B | RNA binding motif protein 15B | -3.04403 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.76522 |
| PRDX1 | peroxiredoxin 1 | -2.70094 |
| PPOX | protoporphyrinogen oxidase | -2.59531 |
| HEATR1 | HEAT repeat containing 1 | -2.57368 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.48635 |
| NUP62 | nucleoporin 62kDa | -2.45373 |
| HNMT | histamine N-methyltransferase | -2.43678 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -2.43016 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.38471 |
| ATAD5 | ATPase family, AAA domain containing 5 | -2.16395 |
| PLP1 | proteolipid protein 1 | -2.13693 |
| MAGEL2 | melanoma antigen family L2 | -2.11712 |
| ACSM1 | acyl-CoA synthetase medium-chain family member 1 | -2.10045 |
| CCDC170 | coiled-coil domain containing 170 | -2.09141 |
| BLVRB | biliverdin reductase B | -2.04107 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -2.01068 |
